6WG7
Coordinates of NanR dimer fitted in Hexameric NanR-DNA hetero-complex cryo-EM map
Summary for 6WG7
Entry DOI | 10.2210/pdb6wg7/pdb |
EMDB information | 21652 21661 |
Descriptor | DNA (35-MER), HTH-type transcriptional repressor NanR (3 entities in total) |
Functional Keywords | nanr dimer-dna hetero-complex, transcriptional regulator, gntr superfamily, sialic acid, neu5ac, cooperativity, gene regulation., gene regulation |
Biological source | Escherichia coli More |
Total number of polymer chains | 8 |
Total formula weight | 198928.06 |
Authors | Hariprasad, V.,Horne, C.,Santosh, P.,Amy, H.,Emre, B.,Rachel, N.,Michael, G.,Georg, R.,Borries, D.,Renwick, D. (deposition date: 2020-04-05, release date: 2021-03-10, Last modification date: 2024-03-06) |
Primary citation | Horne, C.R.,Venugopal, H.,Panjikar, S.,Wood, D.M.,Henrickson, A.,Brookes, E.,North, R.A.,Murphy, J.M.,Friemann, R.,Griffin, M.D.W.,Ramm, G.,Demeler, B.,Dobson, R.C.J. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism. Nat Commun, 12:1988-1988, 2021 Cited by PubMed: 33790291DOI: 10.1038/s41467-021-22253-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (8.3 Å) |
Structure validation
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