6WG7

Coordinates of NanR dimer fitted in Hexameric NanR-DNA hetero-complex cryo-EM map

Summary for 6WG7

• Entry DOI: 10.2210/pdb6wg7/pdb
• EMDB information: 21652 21661
• Descriptor: DNA (35-MER), HTH-type transcriptional repressor NanR (3 entities in total)
• Functional Keywords: nanr dimer-dna hetero-complex, transcriptional regulator, gntr superfamily, sialic acid, neu5ac, cooperativity, gene regulation., gene regulation
• Biological source: Escherichia coli; More
• Total number of polymer chains: 8
• Total formula weight: 198928.06

Authors

Hariprasad, V.,Horne, C.,Santosh, P.,Amy, H.,Emre, B.,Rachel, N.,Michael, G.,Georg, R.,Borries, D.,Renwick, D. (deposition date: 2020-04-05, release date: 2021-03-10, Last modification date: 2024-03-06)

• Primary citation: Horne, C.R.,Venugopal, H.,Panjikar, S.,Wood, D.M.,Henrickson, A.,Brookes, E.,North, R.A.,Murphy, J.M.,Friemann, R.,Griffin, M.D.W.,Ramm, G.,Demeler, B.,Dobson, R.C.J.; Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism.; Nat Commun, 12:1988-1988, 2021; PubMed: 33790291; DOI: 10.1038/s41467-021-22253-6

Experimental method

ELECTRON MICROSCOPY (8.3 Å)