2JM0
 
 | | Solution structure of chicken villin headpiece subdomain containing a fluorinated side chain in the core | | Descriptor: | Villin-1 | | Authors: | Cornilescu, C.C, Cornilescu, G, Hadley, E.B, Gellman, S.H, Markley, J.L. | | Deposit date: | 2006-09-06 | | Release date: | 2006-10-17 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a small protein containing a fluorinated side chain in the core.
Protein Sci., 16, 2007
|
|
6D3O
 | |
4BPJ
 | | Mcl-1 bound to alpha beta Puma BH3 peptide 3 | | Descriptor: | ALPHA BETA BH3-PEPTIDE, CHLORIDE ION, FUSION PROTEIN CONSISTING OF INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1 HOMOLOG, ... | | Authors: | Smith, B.J, Lee, E.F, Checco, J.W, Gellman, S.H, Fairlie, W.D. | | Deposit date: | 2013-05-27 | | Release date: | 2014-04-09 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.599 Å) | | Cite: | Structure-Guided Rational Design of Alpha/Beta-Peptide Foldamers with High Affinity for Bcl-2 Family Prosurvival Proteins.
Chembiochem, 14, 2013
|
|
4BPI
 | | Mcl-1 bound to alpha beta Puma BH3 peptide 2 | | Descriptor: | ALPHA BETA BH3PEPTIDE, CADMIUM ION, FUSION PROTEIN CONSISTING OF INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1 HOMOLOG | | Authors: | Smith, B.J, Lee, E.F, Checco, J.W, Gellman, S.H, Fairlie, W.D. | | Deposit date: | 2013-05-27 | | Release date: | 2014-04-09 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.982 Å) | | Cite: | Structure-Guided Rational Design of Alpha/Beta-Peptide Foldamers with High Affinity for Bcl-2 Family Prosurvival Proteins.
Chembiochem, 14, 2013
|
|
4BPK
 | | Bcl-xL bound to alpha beta Puma BH3 peptide 5 | | Descriptor: | 1,2-ETHANEDIOL, ALPHA BETA BH3-PEPTIDE, BCL-2-LIKE PROTEIN 1, ... | | Authors: | Smith, B.J, Lee, E.F, Checco, J.W, Gellman, S.H, Fairlie, W.D. | | Deposit date: | 2013-05-27 | | Release date: | 2014-04-09 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.756 Å) | | Cite: | Structure-Guided Rational Design of Alpha/Beta-Peptide Foldamers with High Affinity for Bcl-2 Family Prosurvival Proteins.
Chembiochem, 14, 2013
|
|
4A1W
 | | Crystal structure of alpha-beta foldamer 4c in complex with Bcl-xL | | Descriptor: | ALPHA-BETA-FOLDAMER 2C, BCL-2-LIKE PROTEIN 1 | | Authors: | Boersma, M.D, Haase, H.S, Kaufman, K.J, Horne, W.S, Lee, E.F, Clarke, O.B, Smith, B.J, Colman, P.M, Gellman, S.H, Fairlie, W.D. | | Deposit date: | 2011-09-20 | | Release date: | 2011-12-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.497 Å) | | Cite: | Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain.
J.Am.Chem.Soc., 134, 2012
|
|
4A1U
 | | Crystal structure of alpha-beta-foldamer 2c in complex with Bcl-xL | | Descriptor: | ALPHA-BETA-FOLDAMER 2C, BCL-2-LIKE PROTEIN 1, CHLORIDE ION, ... | | Authors: | Boersma, M.D, Haase, H.S, Kaufman, K.J, Horne, W.S, Lee, E.F, Clarke, O.B, Smith, B.J, Colman, P.M, Gellman, S.H, Fairlie, W.D. | | Deposit date: | 2011-09-20 | | Release date: | 2011-12-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain.
J.Am.Chem.Soc., 134, 2012
|
|
3O43
 | |
3O40
 | | Complex of a chimeric alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5 | | Descriptor: | CHLORIDE ION, GLYCEROL, NONAETHYLENE GLYCOL, ... | | Authors: | Horne, W.S, Johnson, L.M, Gellman, S.H. | | Deposit date: | 2010-07-26 | | Release date: | 2011-07-27 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Broad Distribution of Energetically Important Contacts across an Extended Protein Interface.
J.Am.Chem.Soc., 133, 2011
|
|
3O42
 | |
1JY9
 | | MINIMIZED AVERAGE STRUCTURE OF DP-TT2 | | Descriptor: | DP-TT2 | | Authors: | Stanger, H.E, Syud, F.A, Espinosa, J.F, Giriat, I, Muir, T, Gellman, S.H. | | Deposit date: | 2001-09-11 | | Release date: | 2001-09-19 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Length-dependent stability and strand length limits in antiparallel beta -sheet secondary structure.
Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
3O3Z
 | |
3O3X
 | | Crystal structure of gp41-5, a single-chain 5-helix-bundle based on HIV gp41 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ISOPROPYL ALCOHOL, gp41-5 | | Authors: | Horne, W.S, Johnson, L.M, Gellman, S.H. | | Deposit date: | 2010-07-26 | | Release date: | 2011-07-27 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Broad Distribution of Energetically Important Contacts across an Extended Protein Interface.
J.Am.Chem.Soc., 133, 2011
|
|
4MGP
 | | Structure of racemic Ala-(8,13,18) Magainin 2 | | Descriptor: | Magainin 2 Derivative | | Authors: | Hayouka, Z, Mortenson, D.E, Kreitler, D.F, Weisblum, B, Gellman, S.H, Forest, K.T. | | Deposit date: | 2013-08-28 | | Release date: | 2013-10-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Evidence for Phenylalanine Zipper-Mediated Dimerization in the X-ray Crystal Structure of a Magainin 2 Analogue.
J.Am.Chem.Soc., 135, 2013
|
|
2N6H
 | |
2N6I
 | |
2OXJ
 | | Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers: GCN4-p1 with beta-residues at b and f heptad positions. | | Descriptor: | ACETATE ION, hybrid alpha/beta peptide based on the GCN4-p1 sequence; heptad positions b and f substituted with beta-amino acids | | Authors: | Horne, W.S, Price, J.L, Keck, J.L, Gellman, S.H. | | Deposit date: | 2007-02-20 | | Release date: | 2007-03-27 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers.
J.Am.Chem.Soc., 129, 2007
|
|
2OXK
 | | Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers: GCN4-pLI with beta-residues at b and f heptad positions. | | Descriptor: | FORMIC ACID, hybrid alpha/beta peptide based on the GCN4-pLI sequence; heptad positions b and f substituted with beta-amino acids | | Authors: | Horne, W.S, Price, J.L, Keck, J.L, Gellman, S.H. | | Deposit date: | 2007-02-20 | | Release date: | 2007-03-27 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers.
J.Am.Chem.Soc., 129, 2007
|
|
2N4N
 | |
6MPL
 | | Racemic M2-TM I39A crystallized from racemic detergent | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Matrix protein 2, octyl beta-D-glucopyranoside | | Authors: | Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. | | Deposit date: | 2018-10-07 | | Release date: | 2019-01-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
J. Am. Chem. Soc., 141, 2019
|
|
6MPN
 | | Racemic M2-TM I42E crystallized from racemic detergent | | Descriptor: | Matrix protein 2, octyl beta-D-glucopyranoside | | Authors: | Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. | | Deposit date: | 2018-10-07 | | Release date: | 2019-01-30 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
J. Am. Chem. Soc., 141, 2019
|
|
6MPM
 | | Racemic M2-TM I42A crystallized from racemic detergent | | Descriptor: | Matrix protein 2, octyl beta-D-glucopyranoside | | Authors: | Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. | | Deposit date: | 2018-10-07 | | Release date: | 2019-01-30 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
J. Am. Chem. Soc., 141, 2019
|
|
6NIV
 | | Racemic Phenol-Soluble Modulin Alpha 3 Peptide | | Descriptor: | Phenol-soluble modulin PSM-alpha-3 | | Authors: | Yao, Z, Cary, B.P, Bingman, C.A, Wang, C, Kreitler, D.F, Satyshur, K.A, Forest, K.T, Gellman, S.H. | | Deposit date: | 2018-12-31 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin alpha 3 Toxicity.
J.Am.Chem.Soc., 141, 2019
|
|
6NTX
 | |
6NRO
 | | Human parainfluenza virus type 3 fusion protein N-terminal heptad repeat domain+VIQKI | | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Human parainfluenza virus type 3 fusion glycoprotein C-terminal heptad repeat domain, ... | | Authors: | Outlaw, V.K, Kreitler, D.F, Gellman, S.H. | | Deposit date: | 2019-01-23 | | Release date: | 2019-07-17 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Dual Inhibition of Human Parainfluenza Type 3 and Respiratory Syncytial Virus Infectivity with a Single Agent.
J.Am.Chem.Soc., 141, 2019
|
|
