5LAL
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![BU of 5lal by Molmil](/molmil-images/mine/5lal) | Structure of Arabidopsis dirigent protein AtDIR6 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dirigent protein 6, ... | Authors: | Gasper, R, Kolesinski, P, Terlecka, B, Effenberger, I, Schaller, A, Hofmann, E. | Deposit date: | 2016-06-14 | Release date: | 2016-11-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Dirigent Protein Mode of Action Revealed by the Crystal Structure of AtDIR6. Plant Physiol., 172, 2016
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4TQ2
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![BU of 4tq2 by Molmil](/molmil-images/mine/4tq2) | Structure of S-type Phycobiliprotein Lyase CPES from Guillardia theta | Descriptor: | HEXANE-1,6-DIOL, Putative phycoerythrin lyase | Authors: | Gasper, R, Overkamp, K.E, Frankenberg-Dinkel, N, Hofmann, E. | Deposit date: | 2014-06-10 | Release date: | 2014-08-13 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Insights into the Biosynthesis and Assembly of Cryptophycean Phycobiliproteins. J.Biol.Chem., 289, 2014
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5HI8
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![BU of 5hi8 by Molmil](/molmil-images/mine/5hi8) | Structure of T-type Phycobiliprotein Lyase CpeT from Prochlorococcus phage P-HM1 | Descriptor: | ACETATE ION, Antenna protein, MAGNESIUM ION | Authors: | Gasper, R, Schwach, J, Frankenberg-Dinkel, N, Hofmann, E. | Deposit date: | 2016-01-11 | Release date: | 2017-01-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Distinct Features of Cyanophage-encoded T-type Phycobiliprotein Lyase Phi CpeT: THE ROLE OF AUXILIARY METABOLIC GENES. J. Biol. Chem., 292, 2017
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2HF9
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![BU of 2hf9 by Molmil](/molmil-images/mine/2hf9) | Crystal structure of HypB from Methanocaldococcus jannaschii in the triphosphate form | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Probable hydrogenase nickel incorporation protein hypB, ... | Authors: | Gasper, R, Scrima, A, Wittinghofer, A. | Deposit date: | 2006-06-23 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into HypB, a GTP-binding protein that regulates metal binding. J.Biol.Chem., 281, 2006
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2HF8
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![BU of 2hf8 by Molmil](/molmil-images/mine/2hf8) | Crystal structure of HypB from Methanocaldococcus jannaschii in the triphosphate form, in complex with zinc | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Probable hydrogenase nickel incorporation protein hypB, ... | Authors: | Gasper, R, Scrima, A, Wittinghofer, A. | Deposit date: | 2006-06-23 | Release date: | 2006-07-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into HypB, a GTP-binding protein that regulates metal binding. J.Biol.Chem., 281, 2006
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8ABX
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![BU of 8abx by Molmil](/molmil-images/mine/8abx) | Crystal structure of IDO1 in complex with Apoxidole-1 | Descriptor: | Indoleamine 2,3-dioxygenase 1, O1-tert-butyl O2-ethyl O5-methyl (E,5R)-5-(1-methylindol-2-yl)-5-[(4-methylphenyl)sulfonylamino]pent-2-ene-1,2,5-tricarboxylate, O2-tert-butyl O3-ethyl O6-methyl (2S,6R)-6-(1-methylindol-2-yl)-2,5-dihydro-1H-pyridine-2,3,6-tricarboxylate, ... | Authors: | Dotsch, L, Ziegler, S, Waldmann, H, Gasper, R. | Deposit date: | 2022-07-05 | Release date: | 2022-08-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Identification of a Novel Pseudo-Natural Product Type IV IDO1 Inhibitor Chemotype. Angew.Chem.Int.Ed.Engl., 61, 2022
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8BWF
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![BU of 8bwf by Molmil](/molmil-images/mine/8bwf) | PTBP1 RRM1 bound to an allosteric inhibitor | Descriptor: | AMINO GROUP, GLYCEROL, Ligand, ... | Authors: | Schmeing, S, Vetter, I, t Hart, P, Gasper, R. | Deposit date: | 2022-12-06 | Release date: | 2023-10-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Rationally designed stapled peptides allosterically inhibit PTBP1-RNA-binding. Chem Sci, 14, 2023
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5IXB
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![BU of 5ixb by Molmil](/molmil-images/mine/5ixb) | Structure of human Melanoma Inhibitory Activity (MIA) Protein in complex with Pyrimidin-2-amine | Descriptor: | ACETATE ION, Melanoma-derived growth regulatory protein, PYRIMIDIN-2-AMINE | Authors: | Yip, K.T, Gasper, R, Zhong, X.Y, Seibel, N, Puetz, S, Autzen, J, Scherkenbeck, J, Hofmann, E, Stoll, R. | Deposit date: | 2016-03-23 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Small Molecules Antagonise the MIA-Fibronectin Interaction in Malignant Melanoma. Sci Rep, 6, 2016
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8C7I
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![BU of 8c7i by Molmil](/molmil-images/mine/8c7i) | |
7BOC
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![BU of 7boc by Molmil](/molmil-images/mine/7boc) | Crystal structure of the PRMT5 TIM barrel domain in complex with RioK1 peptide | Descriptor: | Protein arginine N-methyltransferase 5, peptide | Authors: | Krzyzanowski, A, t Hart, P, Waldmann, H, Gasper, R. | Deposit date: | 2021-01-25 | Release date: | 2021-09-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5-MEP50 Complex. Chembiochem, 22, 2021
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3BH7
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![BU of 3bh7 by Molmil](/molmil-images/mine/3bh7) | Crystal structure of the RP2-Arl3 complex bound to GDP-AlF4 | Descriptor: | ADP-ribosylation factor-like protein 3, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Veltel, S, Gasper, R, Wittinghofer, A. | Deposit date: | 2007-11-28 | Release date: | 2008-03-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3 Nat.Struct.Mol.Biol., 15, 2008
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3BH6
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![BU of 3bh6 by Molmil](/molmil-images/mine/3bh6) | Crystal structure of the RP2-Arl3 complex bound to GppNHp | Descriptor: | ADP-ribosylation factor-like protein 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Veltel, S, Gasper, R, Wittinghofer, A. | Deposit date: | 2007-11-28 | Release date: | 2008-03-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3 Nat.Struct.Mol.Biol., 15, 2008
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5NS6
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![BU of 5ns6 by Molmil](/molmil-images/mine/5ns6) | Crystal structure of beta-glucosidase BglM-G1 from marine metagenome | Descriptor: | Beta-glucosidase, GLYCEROL, SULFATE ION | Authors: | Mhaindarkar, D.C, Gasper, R, Lupilova, N, Leichert, L.I, Hofmann, E. | Deposit date: | 2017-04-25 | Release date: | 2018-08-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Loss of a conserved salt bridge in bacterial glycosyl hydrolase BgIM-G1 improves substrate binding in temperate environments. Commun Biol, 1, 2018
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8R1I
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![BU of 8r1i by Molmil](/molmil-images/mine/8r1i) | |
5NS8
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![BU of 5ns8 by Molmil](/molmil-images/mine/5ns8) | Crystal structure of beta-glucosidase BglM-G1 mutant H75R from marine metagenome in complex with inhibitor 1-Deoxynojirimycin | Descriptor: | 1-DEOXYNOJIRIMYCIN, GLYCEROL, SULFATE ION, ... | Authors: | Mhaindarkar, D.C, Gasper, R, Lupilova, N, Leichert, L.I, Hofmann, E. | Deposit date: | 2017-04-25 | Release date: | 2018-08-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Loss of a conserved salt bridge in bacterial glycosyl hydrolase BgIM-G1 improves substrate binding in temperate environments. Commun Biol, 1, 2018
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5NS7
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![BU of 5ns7 by Molmil](/molmil-images/mine/5ns7) | Crystal structure of beta-glucosidase BglM-G1 mutant H75R from marine metagenome | Descriptor: | GLYCEROL, SULFATE ION, beta-glucosidase M - G1 | Authors: | Mhaindarkar, D.C, Gasper, R, Lupilova, N, Leichert, L.I, Hofmann, E. | Deposit date: | 2017-04-25 | Release date: | 2018-08-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Loss of a conserved salt bridge in bacterial glycosyl hydrolase BgIM-G1 improves substrate binding in temperate environments. Commun Biol, 1, 2018
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6RMK
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![BU of 6rmk by Molmil](/molmil-images/mine/6rmk) | Bacteriorhodopsin, dark state, cell 2, refined using the same protocol as sub-ps time delays | Descriptor: | Bacteriorhodopsin, RETINAL | Authors: | Nass Kovacs, G, Colletier, J.-P, Gruenbein, M.L, Stensitzki, T, Batyuk, A, Carbajo, S, Doak, R.B, Ehrenberg, D, Foucar, L, Gasper, R, Gorel, A, Hilpert, M, Kloos, M, Koglin, J, Reinstein, J, Roome, C.M, Schlesinger, R, Seaberg, M, Shoeman, R.L, Stricker, M, Boutet, S, Haacke, S, Heberle, J, Domratcheva, T, Barends, T.R.M, Schlichting, I. | Deposit date: | 2019-05-07 | Release date: | 2019-06-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin. Nat Commun, 10, 2019
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6SBA
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![BU of 6sba by Molmil](/molmil-images/mine/6sba) | Crystal Structure of mTEAD with a VGL4 Tertiary Structure Mimetic | Descriptor: | ACETYL GROUP, GLYCEROL, Transcriptional enhancer factor TEF-3, ... | Authors: | Adihou, H, Grossmann, T.N, Waldmann, H, Gasper, R. | Deposit date: | 2019-07-19 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | A protein tertiary structure mimetic modulator of the Hippo signalling pathway. Nat Commun, 11, 2020
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6RXQ
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![BU of 6rxq by Molmil](/molmil-images/mine/6rxq) | Crystal structure of CobB Ac2 (A76G,I131C,V162A) in complex with H4K16Cr-2'OH-ADPr peptide intermediate after soaking | Descriptor: | Histone H4, NAD-dependent protein deacylase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{S})-4-[(~{E})-but-2-enoxy]-3,5-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | Authors: | Spinck, M, Gasper, R, Neumann, H. | Deposit date: | 2019-06-08 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Evolved, Selective Erasers of Distinct Lysine Acylations. Angew.Chem.Int.Ed.Engl., 59, 2020
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6RXK
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![BU of 6rxk by Molmil](/molmil-images/mine/6rxk) | Crystal structure of CobB wt in complex with H4K16-Butyryl peptide | Descriptor: | Histone H4, NAD-dependent protein deacylase, ZINC ION | Authors: | Spinck, M, Gasper, R, Neumann, H. | Deposit date: | 2019-06-08 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Evolved, Selective Erasers of Distinct Lysine Acylations. Angew.Chem.Int.Ed.Engl., 59, 2020
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6RXS
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![BU of 6rxs by Molmil](/molmil-images/mine/6rxs) | Crystal structure of CobB Ac3(A76G,Y92A, I131L, V187Y) in complex with H4K16-Acetyl peptide | Descriptor: | GLYCEROL, Histone H4, NAD-dependent protein deacylase, ... | Authors: | Spinck, M, Gasper, R, Neumann, H. | Deposit date: | 2019-06-08 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Evolved, Selective Erasers of Distinct Lysine Acylations. Angew.Chem.Int.Ed.Engl., 59, 2020
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6RXJ
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![BU of 6rxj by Molmil](/molmil-images/mine/6rxj) | Crystal structure of CobB wt in complex with H4K16-Acetyl peptide | Descriptor: | Histone H4, NAD-dependent protein deacylase, ZINC ION | Authors: | Spinck, M, Gasper, R, Neumann, H. | Deposit date: | 2019-06-08 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Evolved, Selective Erasers of Distinct Lysine Acylations. Angew.Chem.Int.Ed.Engl., 59, 2020
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6RXL
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![BU of 6rxl by Molmil](/molmil-images/mine/6rxl) | Crystal structure of CobB wt in complex with H4K16-Crotonyl peptide | Descriptor: | Histone H4, NAD-dependent protein deacylase, ZINC ION | Authors: | Spinck, M, Gasper, R, Neumann, H. | Deposit date: | 2019-06-08 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Evolved, Selective Erasers of Distinct Lysine Acylations. Angew.Chem.Int.Ed.Engl., 59, 2020
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6RXR
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![BU of 6rxr by Molmil](/molmil-images/mine/6rxr) | Crystal structure of CobB Ac2 (A76G, I131C, V162G) in complex with H4K16Cr-2'OH-ADPr peptide intermediate after co-crystallisation | Descriptor: | Histone H4, NAD-dependent protein deacylase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{S})-4-[(~{E})-but-2-enoxy]-3,5-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | Authors: | Spinck, M, Gasper, R, Neumann, H. | Deposit date: | 2019-06-08 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Evolved, Selective Erasers of Distinct Lysine Acylations. Angew.Chem.Int.Ed.Engl., 59, 2020
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6RXP
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![BU of 6rxp by Molmil](/molmil-images/mine/6rxp) | Crystal structure of CobB Ac2 (A76G,I131C,V162A) in complex with H4K16-Crotonyl peptide | Descriptor: | Histone H4, NAD-dependent protein deacylase, ZINC ION | Authors: | Spinck, M, Gasper, R, Neumann, H. | Deposit date: | 2019-06-08 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evolved, Selective Erasers of Distinct Lysine Acylations. Angew.Chem.Int.Ed.Engl., 59, 2020
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