7BOC

Crystal structure of the PRMT5 TIM barrel domain in complex with RioK1 peptide

Summary for 7BOC

Entry DOI	10.2210/pdb7boc/pdb
Descriptor	Protein arginine N-methyltransferase 5, peptide (2 entities in total)
Functional Keywords	tim barrel, methyltransferase, histones, chromatin-regulator, protein-peptide interaction, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	34873.76
Authors	Krzyzanowski, A.,t Hart, P.,Waldmann, H.,Gasper, R. (deposition date: 2021-01-25, release date: 2021-09-15, Last modification date: 2024-01-31)
Primary citation	Krzyzanowski, A.,Gasper, R.,Adihou, H.,t Hart, P.,Waldmann, H. Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5-MEP50 Complex. Chembiochem, 22:1908-1914, 2021 Cited by PubMed: 33624332 DOI: 10.1002/cbic.202100079 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation