8R1I

Human Carbonic Anhydrase II (hCAII) in complex with (R)-N-(3-Indol-1-yl-2-methyl-propyl)-4-sulfamoyl-benzamide

Summary for 8R1I

• Entry DOI: 10.2210/pdb8r1i/pdb
• Descriptor: Carbonic anhydrase 2, (R)-N-(3-INDOL-1-YL-2-METHYL-PROPYL)-4-SULFAMOYL-BENZAMIDE, ZINC ION, ... (4 entities in total)
• Functional Keywords: inhibitor, carbonic anhydrase, co-crystallization, complex, zn2+ coordination site, metal binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 30243.45

Authors

Kotschy, J.,Gasper, R.,Linser, R. (deposition date: 2023-11-02, release date: 2023-12-06, Last modification date: 2024-01-31)

• Primary citation: Kotschy, J.,Soldner, B.,Singh, H.,Vasa, S.K.,Linser, R.; Microsecond Timescale Conformational Dynamics of a Small-Molecule Ligand within the Active Site of a Protein.; Angew.Chem.Int.Ed.Engl., 63:e202313947-e202313947, 2024; PubMed: 37974542; DOI: 10.1002/anie.202313947

Experimental method

X-RAY DIFFRACTION (1.46 Å)