8ABX

Crystal structure of IDO1 in complex with Apoxidole-1

Summary for 8ABX

Entry DOI	10.2210/pdb8abx/pdb
Descriptor	Indoleamine 2,3-dioxygenase 1, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... (6 entities in total)
Functional Keywords	heme-binding protein, natural product, indoleamine 2, 3-dioxygenase 1, oxidoreductase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	47545.67
Authors	Dotsch, L.,Ziegler, S.,Waldmann, H.,Gasper, R. (deposition date: 2022-07-05, release date: 2022-08-24, Last modification date: 2024-01-31)
Primary citation	Davies, C.,Dotsch, L.,Ciulla, M.G.,Hennes, E.,Yoshida, K.,Gasper, R.,Scheel, R.,Sievers, S.,Strohmann, C.,Kumar, K.,Ziegler, S.,Waldmann, H. Identification of a Novel Pseudo-Natural Product Type IV IDO1 Inhibitor Chemotype. Angew.Chem.Int.Ed.Engl., 61:e202209374-e202209374, 2022 Cited by PubMed: 35959923 DOI: 10.1002/anie.202209374 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation