8ABX
Crystal structure of IDO1 in complex with Apoxidole-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Indoleamine 2,3-dioxygenase 1 | polymer | 404 | 45367.2 | 1 | UniProt (P14902) Pfam (PF01231) | Homo sapiens (human) | IDO-1,Indoleamine-pyrrole 2,3-dioxygenase |
| 2 | B, F (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 3 | C, D, E, G, H (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 5 | Chemie (PGE) | |||
| 4 | I (A) | O1-tert-butyl O2-ethyl O5-methyl (E,5R)-5-(1-methylindol-2-yl)-5-[(4-methylphenyl)sulfonylamino]pent-2-ene-1,2,5-tricarboxylate | non-polymer | 596.7 | 1 | Chemie (N39) | |||
| 5 | J (A) | O2-tert-butyl O3-ethyl O6-methyl (2S,6R)-6-(1-methylindol-2-yl)-2,5-dihydro-1H-pyridine-2,3,6-tricarboxylate | non-polymer | 442.5 | 1 | Chemie (N2U) | |||
| 6 | K (A) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A: 5 - 400 (UniProt: P14902)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Ile 3 | - | expression tag |
| Gln 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45367.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2178.5 | |
| All* | Total formula weight | 47545.7 |
