6PZQ
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8QQK
| Cryo-EM structure of E. coli cytochrome bo3 quinol oxidase assembled in peptidiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, ... | Authors: | Gao, Y, Zhang, Y, Hakke, S, Peters, P.J, Ravelli, R.B.G. | Deposit date: | 2023-10-05 | Release date: | 2024-04-24 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM structure of cytochrome bo 3 quinol oxidase assembled in peptidiscs reveals an "open" conformation for potential ubiquinone-8 release. Biochim Biophys Acta Bioenerg, 1865, 2024
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5L9X
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6OYA
| Structure of the Rhodopsin-Transducin-Nanobody Complex | Descriptor: | Camelid antibody VHH fragment, Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G. | Deposit date: | 2019-05-14 | Release date: | 2019-07-24 | Last modified: | 2019-12-04 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation. Mol.Cell, 75, 2019
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6OY9
| Structure of the Rhodopsin-Transducin Complex | Descriptor: | Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... | Authors: | Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G. | Deposit date: | 2019-05-14 | Release date: | 2019-07-24 | Last modified: | 2019-12-04 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation. Mol.Cell, 75, 2019
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1CL4
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8HR7
| Structure of RdrA-RdrB complex | Descriptor: | Adenosine deaminase, Archaeal ATPase | Authors: | Gao, Y. | Deposit date: | 2022-12-15 | Release date: | 2023-02-01 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HR8
| Structure of heptameric RdrA ring | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Archaeal ATPase | Authors: | Gao, Y. | Deposit date: | 2022-12-15 | Release date: | 2023-02-01 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HRC
| Structure of dodecameric RdrB cage | Descriptor: | Adenosine deaminase | Authors: | Gao, Y. | Deposit date: | 2022-12-15 | Release date: | 2023-02-01 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HRB
| Structure of tetradecameric RdrA ring in RNA-loading state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Archaeal ATPase, RNA (5'-R(*GP*UP*CP*CP*AP*GP*CP*GP*UP*CP*AP*UP*CP*GP*CP*UP*GP*GP*AP*C)-3') | Authors: | Gao, Y. | Deposit date: | 2022-12-15 | Release date: | 2023-02-01 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HR9
| Structure of tetradecameric RdrA ring | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Archaeal ATPase | Authors: | Gao, Y. | Deposit date: | 2022-12-15 | Release date: | 2023-02-01 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HRA
| Structure of heptameric RdrA ring in RNA-loading state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Archaeal ATPase, RNA (5'-R(P*GP*UP*CP*CP*AP*GP*CP*GP*UP*CP*AP*UP*CP*GP*CP*UP*GP*GP*AP*C)-3') | Authors: | Gao, Y. | Deposit date: | 2022-12-15 | Release date: | 2023-02-01 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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2DU9
| crystal structure of the transcriptional factor from C.glutamicum | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Predicted transcriptional regulators | Authors: | Gao, Y, Yao, M, Tanaka, I. | Deposit date: | 2006-07-20 | Release date: | 2007-07-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | The structures of transcription factor CGL2947 from Corynebacterium glutamicum in two crystal forms: A novel homodimer assembling and the implication for effector-binding mode Protein Sci., 16, 2007
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8FTI
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2MDJ
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8E2L
| Structure of Lates calcarifer Twinkle helicase with ATP and DNA | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | Authors: | Gao, Y, Li, Z. | Deposit date: | 2022-08-15 | Release date: | 2022-11-02 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Structural and dynamic basis of DNA capture and translocation by mitochondrial Twinkle helicase. Nucleic Acids Res., 50, 2022
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7M3G
| Asymmetric Activation of the Calcium Sensing Receptor Homodimer | Descriptor: | 2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G. | Deposit date: | 2021-03-18 | Release date: | 2021-06-30 | Last modified: | 2021-07-21 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Asymmetric activation of the calcium-sensing receptor homodimer. Nature, 595, 2021
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7M3J
| Asymmetric Activation of the Calcium Sensing Receptor Homodimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ... | Authors: | Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G. | Deposit date: | 2021-03-18 | Release date: | 2021-06-30 | Last modified: | 2021-07-21 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Asymmetric activation of the calcium-sensing receptor homodimer. Nature, 595, 2021
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7M3E
| Asymmetric Activation of the Calcium Sensing Receptor Homodimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ... | Authors: | Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G. | Deposit date: | 2021-03-18 | Release date: | 2021-06-30 | Last modified: | 2021-07-21 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Asymmetric activation of the calcium-sensing receptor homodimer. Nature, 595, 2021
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7M3F
| Asymmetric Activation of the Calcium Sensing Receptor Homodimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G. | Deposit date: | 2021-03-18 | Release date: | 2021-06-30 | Last modified: | 2021-07-21 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Asymmetric activation of the calcium-sensing receptor homodimer. Nature, 595, 2021
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8WKJ
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5IRX
| Structure of TRPV1 in complex with DkTx and RTX, determined in lipid nanodisc | Descriptor: | (2S)-2-(acetyloxy)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}propyl pentanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ... | Authors: | Gao, Y, Cao, E, Julius, D, Cheng, Y. | Deposit date: | 2016-03-14 | Release date: | 2016-05-25 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Nature, 534, 2016
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5IS0
| Structure of TRPV1 in complex with capsazepine, determined in lipid nanodisc | Descriptor: | Transient receptor potential cation channel subfamily V member 1, capsazepine | Authors: | Gao, Y, Cao, E, Julius, D, Cheng, Y. | Deposit date: | 2016-03-15 | Release date: | 2016-05-25 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Nature, 534, 2016
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5IRZ
| Structure of TRPV1 determined in lipid nanodisc | Descriptor: | (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(pentanoyloxy)propan-2-yl decanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ... | Authors: | Gao, Y, Cao, E, Julius, D, Cheng, Y. | Deposit date: | 2016-03-15 | Release date: | 2016-05-25 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Nature, 534, 2016
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3UBU
| Crystal structure of agkisacucetin, a GpIb-binding snaclec (snake C-type lectin) that inhibits platelet | Descriptor: | Agglucetin subunit alpha-1, Agglucetin subunit beta-2, GLYCEROL, ... | Authors: | Gao, Y, Ge, H, Chen, H, Li, H, Liu, Y, Niu, L, Teng, M. | Deposit date: | 2011-10-25 | Release date: | 2012-04-11 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Crystal structure of agkisacucetin, a Gpib-binding snake C-type lectin that inhibits platelet adhesion and aggregation. Proteins, 2012
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