7Y1B
| 3.2 angstrom cryo-EM structure of extracellular region of mouse Basigin-2 in complex with the Fab fragment of antibody 6E7F1 | Descriptor: | Heavy chain of 6E7F1, Isoform 2 of Basigin, Light chain of 6E7F1 | Authors: | Zhang, H, Yang, X, Xue, Y, Huang, Y, Mo, X, Zhang, H, Li, N, Gao, N, Li, X, Wang, S, Gao, Y, Liao, J. | Deposit date: | 2022-06-08 | Release date: | 2023-06-14 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin To Be Published
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2R5E
| Aedes kynurenine aminotransferase in complex with glutamine | Descriptor: | Kynurenine aminotransferase, N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-GLUTAMINE | Authors: | Han, Q, Gao, Y.G, Robinson, H, Li, J. | Deposit date: | 2007-09-03 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase. Biochemistry, 47, 2008
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380D
| BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES | Descriptor: | 2'-BROMO-4'-EPIDAUNORUBICIN, DNA (5'-D(*CP*GP*(G49)P*(CBR)P*CP*G)-3') | Authors: | Dutta, R, Gao, Y.-G, Priebe, W, Wang, A.H.-J. | Deposit date: | 1998-02-18 | Release date: | 1998-07-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes. Nucleic Acids Res., 26, 1998
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381D
| BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES | Descriptor: | 2'-BROMO-4'-EPIDAUNORUBICIN, DNA (5'-D(*TP*GP*(G49)P*CP*CP*G)-3'), DNA (5'-D(*TP*GP*GP*CP*CP*G)-3') | Authors: | Dutta, R, Gao, Y.-G, Priebe, W, Wang, A.H.-J. | Deposit date: | 1998-02-18 | Release date: | 1998-07-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes. Nucleic Acids Res., 26, 1998
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2R5C
| Aedes Kynurenine Aminotransferase in Complex with Cysteine | Descriptor: | Kynurenine aminotransferase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE | Authors: | Han, Q, Gao, Y.G, Robinson, H, Li, J. | Deposit date: | 2007-09-03 | Release date: | 2008-03-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase. Biochemistry, 47, 2008
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1K5W
| THREE-DIMENSIONAL STRUCTURE OF THE SYNAPTOTAGMIN 1 C2B-DOMAIN: SYNAPTOTAGMIN 1 AS A PHOSPHOLIPID BINDING MACHINE | Descriptor: | CALCIUM ION, Synaptotagmin I | Authors: | Fernandez, I, Arac, D, Ubach, J, Gerber, S.H, Shin, O, Gao, Y, Anderson, R.G.W, Sudhof, T.C, Rizo, J. | Deposit date: | 2001-10-12 | Release date: | 2002-01-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine. Neuron, 32, 2001
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6L1W
| Zinc-finger Antiviral Protein (ZAP) bound to RNA | Descriptor: | RNA (5'-R(*CP*GP*UP*CP*GP*U)-3'), ZINC ION, Zinc finger CCCH-type antiviral protein 1 | Authors: | Luo, X, Wang, X, Gao, Y, Zhu, J, Liu, S, Gao, G, Gao, P. | Deposit date: | 2019-09-30 | Release date: | 2020-01-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein. Cell Rep, 30, 2020
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7WWK
| Local refinement of the SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab | Descriptor: | 55A8 light chain, Spike glycoprotein | Authors: | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | Deposit date: | 2022-02-13 | Release date: | 2023-02-15 | Last modified: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Local refinement of the SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab To Be Published
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7XJ9
| Local refinement of the SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab and 58G6 Fab | Descriptor: | 55A8 heavy chain, 55A8 light chain, 58G6 heavy chain, ... | Authors: | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | Deposit date: | 2022-04-15 | Release date: | 2023-04-19 | Last modified: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Local refinement of the SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab and 58G6 Fab To Be Published
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2ZDS
| Crystal Structure of SCO6571 from Streptomyces coelicolor A3(2) | Descriptor: | Putative DNA-binding protein | Authors: | Begum, P, Gao, Y.G, Sakai, N, Yao, M, Watanabe, N, Tanaka, I. | Deposit date: | 2007-11-27 | Release date: | 2008-12-02 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of SCO6571 from Streptomyces coelicolor A3(2). Protein Pept.Lett., 15, 2008
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8SZI
| Cryo-EM structure of PAM-free human calcium-sensing receptor CaSR-Gi complex in lipid nanodiscs | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | He, F, Wu, C, Gao, Y, Skiniotis, G. | Deposit date: | 2023-05-29 | Release date: | 2024-02-07 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor. Nature, 626, 2024
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8TAZ
| Cryo-EM structure of mink variant Y453F trimeric spike protein bound to one mink ACE2 receptors | Descriptor: | Angiotensin-converting enzyme, Spike glycoprotein | Authors: | Ahn, H.M, Calderon, B, Fan, X, Gao, Y, Horgan, N, Liang, B. | Deposit date: | 2023-06-28 | Release date: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2. J Med Virol, 95, 2023
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8ZX1
| Cryo-EM structure of E.coli spermidine transporter PotABC in nanodisc | Descriptor: | Spermidine/putrescine ABC transporter membrane protein, Spermidine/putrescine import ATP-binding protein PotA, Spermidine/putrescine transport system permease protein PotC | Authors: | Qiao, Z, Gao, Y.G. | Deposit date: | 2024-06-13 | Release date: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into polyamine spermidine uptake by the ABC transporter PotD-PotABC. Sci Adv, 10, 2024
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8Y5H
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8Y5F
| Cryo-EM structure of E.coli spermidine transporter PotABC | Descriptor: | Spermidine/putrescine import ATP-binding protein PotA, Spermidine/putrescine transport system permease protein PotB, Spermidine/putrescine transport system permease protein PotC | Authors: | Qiao, Z, Gao, Y.G. | Deposit date: | 2024-01-31 | Release date: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Structural insights into polyamine spermidine uptake by the ABC transporter PotD-PotABC. Sci Adv, 10, 2024
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8Y5G
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8Y5I
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7XR3
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7WWJ
| SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab in the class 2 conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 55A8 heavy chain, ... | Authors: | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | Deposit date: | 2022-02-13 | Release date: | 2023-02-15 | Last modified: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | EM structure of SARS-CoV-2 Omicron variant spike glycoprotein and 55A8 To Be Published
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7WWI
| SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab in the class 1 conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 55A8 heavy chain, ... | Authors: | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | Deposit date: | 2022-02-13 | Release date: | 2023-02-15 | Last modified: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab in the class 1 conformation To Be Published
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7XJ8
| SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab and 58G6 Fab in the class 2 conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 55A8 heavy chain, ... | Authors: | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | Deposit date: | 2022-04-15 | Release date: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab and 58G6 Fab in the class 2 conformation To Be Published
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7XJ6
| SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab and 58G6 Fab in the class 1 conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 55A8 heavy chain, ... | Authors: | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | Deposit date: | 2022-04-15 | Release date: | 2023-04-19 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab and 58G6 Fab in the class 1 conformation To Be Published
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7O6E
| 2.12 A cryo-EM structure of Mycobacterium tuberculosis Ferritin | Descriptor: | Ferritin BfrB | Authors: | Gijsbers, A, Zhang, Y, Gao, Y, Peters, P.J, Ravelli, R.B.G. | Deposit date: | 2021-04-10 | Release date: | 2021-05-19 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Mycobacterium tuberculosis ferritin: a suitable workhorse protein for cryo-EM development. Acta Crystallogr D Struct Biol, 77, 2021
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6O8A
| Thaumatin native-SAD structure determined at 5 keV from microcrystals | Descriptor: | L(+)-TARTARIC ACID, Thaumatin-1 | Authors: | Guo, G, Zhu, P, Fuchs, M.R, Shi, W, Andi, B, Gao, Y, Hendrickson, W.A, McSweeney, S, Liu, Q. | Deposit date: | 2019-03-09 | Release date: | 2019-05-08 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Synchrotron microcrystal native-SAD phasing at a low energy. Iucrj, 6, 2019
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6M7V
| Human DNA polymerase eta extension complex with cdA at the -1 position | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(P*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(P*GP*TP*GP*TP*GP*AP*GP*T)-3'), ... | Authors: | Weng, P, Gao, Y, Yang, W. | Deposit date: | 2018-08-21 | Release date: | 2018-09-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.062 Å) | Cite: | Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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