5WRV
 
 | | Complex structure of human SRP72/SRP68 | | 分子名称: | ACETATE ION, GLYCEROL, SODIUM ION, ... | | 著者 | Gao, Y, Chen, Z. | | 登録日 | 2016-12-04 | | 公開日 | 2017-06-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation
J Mol Cell Biol, 9, 2017
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5WRW
 | | Structure of human apo-SRP72 | | 分子名称: | SULFATE ION, Signal recognition particle subunit SRP72 | | 著者 | Gao, Y, Chen, Z. | | 登録日 | 2016-12-04 | | 公開日 | 2017-06-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation
J Mol Cell Biol, 9, 2017
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7D2W
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7XLQ
 | | Structure of human R-type voltage-gated CaV2.3-alpha2/delta1-beta1 channel complex in the ligand-free (apo) state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Gao, Y, Qiu, Y, Wei, Y, Dong, Y, Zhang, X.C, Zhao, Y. | | 登録日 | 2022-04-22 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Molecular insights into the gating mechanisms of voltage-gated calcium channel Ca V 2.3.
Nat Commun, 14, 2023
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8J77
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8J75
 | | Human high-affinity choline transporter CHT1 in the HC-3-bound outward-facing open conformation, monomeric state | | 分子名称: | (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium), High affinity choline transporter 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Gao, Y, Qiu, Y, Zhao, Y. | | 登録日 | 2023-04-27 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Transport mechanism of presynaptic high-affinity choline uptake by CHT1.
Nat.Struct.Mol.Biol., 31, 2024
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8J76
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8J74
 | | Human high-affinity choline transporter CHT1 in the HC-3-bound outward-facing open conformation, dimeric state | | 分子名称: | (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium), CHOLESTEROL HEMISUCCINATE, HEXADECANE, ... | | 著者 | Gao, Y, Qiu, Y, Zhao, Y. | | 登録日 | 2023-04-27 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Transport mechanism of presynaptic high-affinity choline uptake by CHT1.
Nat.Struct.Mol.Biol., 31, 2024
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7V4T
 | | Cryo-EM structure of Alphavirus M1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ... | | 著者 | Gao, Y, Jia, X, Zhang, Q. | | 登録日 | 2021-08-15 | | 公開日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (4.04 Å) | | 主引用文献 | Cryo-EM evidence of viral N-glycosylation reveal receptor binding mechanisms
of alphavirus M1
To Be Published
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4V7K
 | | Structure of RelE nuclease bound to the 70S ribosome (postcleavage state) | | 分子名称: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | | 著者 | Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E. | | 登録日 | 2009-11-02 | | 公開日 | 2014-07-09 | | 最終更新日 | 2014-12-10 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
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1MNV
 | | Actinomycin D binding to ATGCTGCAT | | 分子名称: | 5'-D(*AP*TP*GP*CP*TP*GP*CP*AP*T)-3', ACTINOMYCIN D | | 著者 | Hou, M.-H, Robinson, H, Gao, Y.-G, Wang, A.H.-J. | | 登録日 | 2002-09-06 | | 公開日 | 2002-11-22 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of Actinomycin D Bound to the Ctg Triplet Repeat Sequences Linked to Neurological Diseases
Nucleic Acids Res., 30, 2002
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4OQT
 | | LINGO-1/Li81 Fab complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Li81 Fab, ... | | 著者 | Pepinsky, R.B, Arndt, J.W, Quan, C, Gao, Y, Quintero-Monzon, O, Lee, X, Mi, S. | | 登録日 | 2014-02-10 | | 公開日 | 2014-05-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | | 主引用文献 | Structure of the LINGO-1-Anti-LINGO-1 Li81 Antibody Complex Provides Insights into the Biology of LINGO-1 and the Mechanism of Action of the Antibody Therapy.
J.Pharmacol.Exp.Ther., 350, 2014
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4O8B
 | | Crystal structure of transcriptional regulator BswR | | 分子名称: | Uncharacterized protein | | 著者 | Ye, F.Z, Wang, C, Kumar, V, Zhang, L.H, Gao, Y.G. | | 登録日 | 2013-12-26 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA rsmZ.
Nucleic Acids Res., 42, 2014
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3KZ3
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3KM8
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6L1W
 | | Zinc-finger Antiviral Protein (ZAP) bound to RNA | | 分子名称: | RNA (5'-R(*CP*GP*UP*CP*GP*U)-3'), ZINC ION, Zinc finger CCCH-type antiviral protein 1 | | 著者 | Luo, X, Wang, X, Gao, Y, Zhu, J, Liu, S, Gao, G, Gao, P. | | 登録日 | 2019-09-30 | | 公開日 | 2020-01-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | | 主引用文献 | Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein.
Cell Rep, 30, 2020
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4FD3
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2L26
 | | Rv0899 from Mycobacterium tuberculosis contains two separated domains | | 分子名称: | Uncharacterized protein Rv0899/MT0922 | | 著者 | Shi, C, Li, J, Gao, Y, Wu, K, Huang, H, Tian, C. | | 登録日 | 2010-08-12 | | 公開日 | 2011-08-17 | | 最終更新日 | 2011-12-07 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Studies of Mycobacterium tuberculosis Rv0899 Reveal a Monomeric Membrane-Anchoring Protein with Two Separate Domains
J.Mol.Biol., 2011
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4FMM
 | | Dimeric Sec14 family homolog 3 from Saccharomyces cerevisiae presents some novel features of structure that lead to a surprising "dimer-monomer" state change induced by substrate binding | | 分子名称: | GLYCEROL, MAGNESIUM ION, Phosphatidylinositol transfer protein PDR16 | | 著者 | Yuan, Y, Zhao, W, Wang, X, Gao, Y, Niu, L, Teng, M. | | 登録日 | 2012-06-18 | | 公開日 | 2013-02-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Dimeric Sfh3 has structural changes in its binding pocket that are associated with a dimer-monomer state transformation induced by substrate binding.
Acta Crystallogr.,Sect.D, 69, 2013
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4GBV
 | | Crystal Structure of AMP complexes of Porcine Liver Fructose-1,6-bisphosphatase Mutant A54L with 1,2-ethanediol as Cryo-protectant | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ... | | 著者 | Honzatko, R.B, Gao, Y. | | 登録日 | 2012-07-28 | | 公開日 | 2013-08-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Water Structure of the Central Hydrophobic Cavity of Mammalian Fructose-1,6-bisphosphatase: a Potential Thermodynamic Determinant of Allowed Quaternary States
To be published
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4V7J
 | | Structure of RelE nuclease bound to the 70S ribosome (precleavage state) | | 分子名称: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | | 著者 | Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E. | | 登録日 | 2009-11-02 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
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7Y3E
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4V90
 | | Thermus thermophilus Ribosome | | 分子名称: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | | 著者 | Chen, Y, Feng, S, Kumar, V, Ero, R, Gao, Y.G. | | 登録日 | 2014-02-22 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure of EF-G-ribosome complex in a pretranslocation state.
Nat. Struct. Mol. Biol., 20, 2013
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8K58
 | | The cryo-EM map of close TIEA-TIC complex | | 分子名称: | 15 kDa RNA polymerase-binding protein, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Zhang, K.N, Liu, Y, Chen, M, Wang, Y, Lin, W, Li, M, Zhang, X, Gao, Y, Gong, Q, Chen, H, Steve, M, Li, S, Zhang, K, Liu, B. | | 登録日 | 2023-07-21 | | 公開日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | TIEA inhibits Sigma70-dependent transcriptions, accelerates elongation speed and elevates transcription error
To Be Published
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8K5A
 | | The cryo-EM map of open TIEA-TIC complex | | 分子名称: | 15 kDa RNA polymerase-binding protein, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Zhang, K.N, Liu, Y, Chen, M, Wang, Y, Lin, W, Li, M, Zhang, X, Gao, Y, Gong, Q, Chen, H, Steve, M, Li, S, Zhang, K, Liu, B. | | 登録日 | 2023-07-21 | | 公開日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | TIEA inhibits sigma70-dependent transcriptions, accelerates elongation speed and elevates transcription error
To Be Published
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