6ISB
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![BU of 6isb by Molmil](/molmil-images/mine/6isb) | crystal structure of human CD226 | Descriptor: | CD226 antigen | Authors: | Wang, H, Qi, J, Zhang, S, Li, Y, Tan, S, Gao, G.F. | Deposit date: | 2018-11-16 | Release date: | 2018-12-26 | Last modified: | 2019-02-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Binding mode of the side-by-side two-IgV molecule CD226/DNAM-1 to its ligand CD155/Necl-5. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6J5F
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![BU of 6j5f by Molmil](/molmil-images/mine/6j5f) | Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein Domain III | Descriptor: | Envelope protein, antibody heavy chain, antibody light chain | Authors: | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | Deposit date: | 2019-01-10 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. J. Virol., 93, 2019
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6J2D
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![BU of 6j2d by Molmil](/molmil-images/mine/6j2d) | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV1 | Descriptor: | HeV1, Ptal-N*01:01, beta-2 microglobulin | Authors: | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | Deposit date: | 2019-01-01 | Release date: | 2019-09-18 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (2.313 Å) | Cite: | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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7W8S
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![BU of 7w8s by Molmil](/molmil-images/mine/7w8s) | Structure of SARS-CoV-2 spike receptor-binding domain Y453F mutation complexed with American mink ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | Authors: | Su, C, Qi, J.X, Gao, G.F. | Deposit date: | 2021-12-08 | Release date: | 2022-08-17 | Last modified: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Molecular Basis of Mink ACE2 Binding to SARS-CoV-2 and Its Mink-Derived Variants. J.Virol., 96, 2022
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7WA1
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![BU of 7wa1 by Molmil](/molmil-images/mine/7wa1) | |
5YGH
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![BU of 5ygh by Molmil](/molmil-images/mine/5ygh) | Crystal Structure of the Capsid Protein from Zika Virus | Descriptor: | Capsid protein | Authors: | Shang, Z, Song, H, Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2017-09-23 | Release date: | 2018-02-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.884 Å) | Cite: | Crystal Structure of the Capsid Protein from Zika Virus. J. Mol. Biol., 430, 2018
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6ISC
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![BU of 6isc by Molmil](/molmil-images/mine/6isc) | complex structure of mCD226-ecto and hCD155-D1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD226 antigen, Poliovirus receptor | Authors: | Wang, H, Qi, J, Zhang, S, Li, Y, Tan, S, Gao, G.F. | Deposit date: | 2018-11-16 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Binding mode of the side-by-side two-IgV molecule CD226/DNAM-1 to its ligand CD155/Necl-5. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5WWI
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![BU of 5wwi by Molmil](/molmil-images/mine/5wwi) | Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1) | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | Authors: | Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F. | Deposit date: | 2017-01-01 | Release date: | 2018-01-17 | Last modified: | 2019-07-31 | Method: | X-RAY DIFFRACTION (3.194 Å) | Cite: | Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1). To Be Published
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5XSQ
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![BU of 5xsq by Molmil](/molmil-images/mine/5xsq) | Crystal Structure of the Marburg Virus Nucleoprotein Core Domain Chaperoned by a VP35 Peptide | Descriptor: | Nucleoprotein, Peptide from Polymerase cofactor VP35 | Authors: | Zhu, T, Song, H, Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2017-06-15 | Release date: | 2017-06-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of the Marburg Virus Nucleoprotein Core Domain Chaperoned by a VP35 Peptide Reveals a Conserved Drug Target for Filovirus J. Virol., 91, 2017
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6KLC
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![BU of 6klc by Molmil](/molmil-images/mine/6klc) | Structure of apo Lassa virus polymerase | Descriptor: | MANGANESE (II) ION, RNA-directed RNA polymerase L | Authors: | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | Deposit date: | 2019-07-30 | Release date: | 2020-03-18 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural insight into arenavirus replication machinery. Nature, 579, 2020
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6KLD
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![BU of 6kld by Molmil](/molmil-images/mine/6kld) | Structure of apo Machupo virus polymerase | Descriptor: | MANGANESE (II) ION, RNA-directed RNA polymerase L, ZINC ION | Authors: | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | Deposit date: | 2019-07-30 | Release date: | 2020-03-18 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Structural insight into arenavirus replication machinery. Nature, 579, 2020
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7XYQ
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![BU of 7xyq by Molmil](/molmil-images/mine/7xyq) | Crystal strucutre of PD-L1 and the computationally designed DBL1_03 protein binder | Descriptor: | ARGININE, CD274 molecule, DBL1_03 | Authors: | Liu, K, Xu, Z, Han, P, Pacesa, M, Gao, G.F, Chai, Y, Tan, S. | Deposit date: | 2022-06-02 | Release date: | 2023-04-12 | Last modified: | 2023-05-17 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | De novo design of protein interactions with learned surface fingerprints. Nature, 617, 2023
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7XNF
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![BU of 7xnf by Molmil](/molmil-images/mine/7xnf) | Structure of SARS-CoV-2 antibody P2C-1F11 with GX/P2V/2017 RBD | Descriptor: | P2C-1F11 Heavy Chain, P2C-1F11 Lambda chain, Spike protein S1 | Authors: | Jia, Y.F, Chai, Y, Wang, Q.H, Gao, G.F. | Deposit date: | 2022-04-28 | Release date: | 2023-01-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Cross-reaction of current available SARS-CoV-2 MAbs against the pangolin-origin coronavirus GX/P2V/2017. Cell Rep, 41, 2022
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5WZ3
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![BU of 5wz3 by Molmil](/molmil-images/mine/5wz3) | Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase(RdRP) | Descriptor: | NS5 RdRp, ZINC ION | Authors: | Duan, W, Song, H, Qi, J, Shi, Y, Gao, G.F. | Deposit date: | 2017-01-16 | Release date: | 2017-03-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.804 Å) | Cite: | The crystal structure of Zika virus NS5 reveals conserved drug targets. EMBO J., 36, 2017
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6KY8
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![BU of 6ky8 by Molmil](/molmil-images/mine/6ky8) | Crystal structure of ASFV dUTPase | Descriptor: | E165R | Authors: | Li, C, Chai, Y, Song, H, Qi, J, Sun, Y, Gao, G.F. | Deposit date: | 2019-09-17 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target. Mbio, 10, 2019
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6J5G
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![BU of 6j5g by Molmil](/molmil-images/mine/6j5g) | Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein | Descriptor: | Envelope protein E, antibody heavy chain, antibody light chain | Authors: | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | Deposit date: | 2019-01-10 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.291 Å) | Cite: | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. J. Virol., 93, 2019
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6J5C
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![BU of 6j5c by Molmil](/molmil-images/mine/6j5c) | Louping ill virus envelope protein | Descriptor: | Envelope protein E | Authors: | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | Deposit date: | 2019-01-10 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. J. Virol., 93, 2019
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6J5D
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![BU of 6j5d by Molmil](/molmil-images/mine/6j5d) | Complex structure of MAb 4.2-scFv with louping ill virus envelope protein Domain III | Descriptor: | Envelope, antibody heavy chain, antibody light chain | Authors: | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | Deposit date: | 2019-01-10 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. J. Virol., 93, 2019
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6KUJ
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![BU of 6kuj by Molmil](/molmil-images/mine/6kuj) | Structure of influenza D virus polymerase bound to cRNA promoter in class 1 | Descriptor: | 3'-cRNA promoter, 5'-cRNA promoter, Polymerase 3, ... | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | Deposit date: | 2019-09-02 | Release date: | 2019-10-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of influenza D virus polymerase bound to cRNA promoter in Mode A conformation NAT NANOTECHNOL, 2019
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7WVM
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![BU of 7wvm by Molmil](/molmil-images/mine/7wvm) | The complex structure of PD-1 and cemiplimab | Descriptor: | Heavy Chain of Cemiplimab, Light Chain of Cemiplimab, Programmed cell death protein 1 | Authors: | Lu, D, Xu, Z.P, Liu, K.F, Tan, S.G, Gao, G.F, Chai, Y. | Deposit date: | 2022-02-10 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy. Front Immunol, 13, 2022
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7WKJ
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![BU of 7wkj by Molmil](/molmil-images/mine/7wkj) | A COVID-19 T-cell response detection method based on a newly identified human CD8+ T cell epitope from SARS-CoV-2-Hubei Province, 2021. | Descriptor: | Beta-2-microglobulin, LYS-THR-PHE-PRO-PRO-THR-GLU-PRO-LYS, MHC class I antigen | Authors: | Zhang, J, Lu, D, Li, M, Liu, M.S, Yao, S.J, Zhan, J.B, Liu, J, Gao, G.F. | Deposit date: | 2022-01-10 | Release date: | 2022-03-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A COVID-19 T-Cell Response Detection Method Based on a Newly Identified Human CD8 + T Cell Epitope from SARS-CoV-2 - Hubei Province, China, 2021. China CDC Wkly, 4, 2022
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7XF3
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![BU of 7xf3 by Molmil](/molmil-images/mine/7xf3) | The structure of HLA-B*1501/BM58-66AF9 | Descriptor: | 9-mer peptide from Matrix protein 1, Beta-2-microglobulin, MHC class I antigen | Authors: | Zhao, Y.Z, Xiao, W.L, Wu, Y.N, Fan, W.F, Yue, C, Zhang, Q.X, Zhang, D.N, Yuan, X.J, Yao, S.J, Liu, S, Li, M, Wang, P.Y, Zhang, H.J, Zhang, J, Zhao, M, Zheng, X.Q, Liu, W.J, Gao, G.F, Liu, W.L. | Deposit date: | 2022-03-31 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape. J Immunol., 210, 2023
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3JTT
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![BU of 3jtt by Molmil](/molmil-images/mine/3jtt) | |
3JTS
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![BU of 3jts by Molmil](/molmil-images/mine/3jts) | GY9-Mamu-A*02-hb2m | Descriptor: | Beta-2-microglobulin, MHC class I Mamu-A*02, peptide of Gag-Pol polyprotein | Authors: | Dai, L, Feng, Y, Qi, J, Gao, G.F. | Deposit date: | 2009-09-14 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Structure of Mamu A*2 To be Published
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