8Y6A
 
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2 and S309 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F. | | 登録日 | 2024-02-02 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Spike structures, receptor binding and immune escape of SARS-CoV-2 Omicron recently-circulating BA.2.86.1, JN.1, EG.5, EG.5.1 and HV.1 sub-variants
To Be Published
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8XLV
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P), 1-RBD-up state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | | 登録日 | 2023-12-26 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants
To Be Published
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8Y5J
 | | Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F. | | 登録日 | 2024-01-31 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Spike structures, receptor binding and immune escape of SARS-CoV-2 Omicron recently-circulating BA.2.86.1, JN.1, EG.5, EG.5.1 and HV.1 sub-variants
To Be Published
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8Y16
 | | Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein in complex with human ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F. | | 登録日 | 2024-01-23 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Spike structures, receptor binding and immune escape of SARS-CoV-2 Omicron recently-circulating BA.2.86.1, JN.1, EG.5, EG.5.1 and HV.1 sub-variants
To Be Published
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1UK4
 | | Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) Complexed With An Inhibitor | | 分子名称: | 3C-like proteinase nsp5, 5-mer peptide of inhibitor | | 著者 | Yang, H, Yang, M, Liu, Y, Bartlam, M, Ding, Y, Lou, Z, Sun, L, Zhou, Z, Ye, S, Anand, K, Pang, H, Gao, G.F, Hilgenfeld, R, Rao, Z. | | 登録日 | 2003-08-14 | | 公開日 | 2003-11-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
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4DFH
 | | Crystal structure of cell adhesion molecule nectin-2/CD112 variable domain | | 分子名称: | Poliovirus receptor-related protein 2 | | 著者 | Liu, J, Qian, X, Chen, Z, Xu, X, Gao, F, Zhang, S, Zhang, R, Qi, J, Gao, G.F, Yan, J. | | 登録日 | 2012-01-23 | | 公開日 | 2012-06-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
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3P2T
 | | Crystal Structure of Leukocyte Ig-like Receptor LILRB4 (ILT3/LIR-5/CD85k) | | 分子名称: | Leukocyte immunoglobulin-like receptor subfamily B member 4, SULFATE ION | | 著者 | Chen, Y, Nam, G, Cheng, H, Zhang, J.H, Willcox, B.E, Gao, G.F. | | 登録日 | 2010-10-04 | | 公開日 | 2011-03-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | | 主引用文献 | Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance
J.Biol.Chem., 286, 2011
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5DO2
 | | Complex structure of MERS-RBD bound with 4C2 antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C2 heavy chain, 4C2 light chain, ... | | 著者 | Li, Y, Wan, Y, Liu, P, Zhao, J, Lu, G, Qi, J, Wang, Q, Lu, X, Wu, Y, Liu, W, Yuen, K.Y, Perlman, S, Gao, G.F, Yan, J. | | 登録日 | 2015-09-10 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.409 Å) | | 主引用文献 | A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein.
Cell Res., 25, 2015
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5F1B
 | | Structural basis of Ebola virus entry: viral glycoprotein bound to its endosomal receptor Niemann-Pick C1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GP1, GP2, ... | | 著者 | Wang, H, Shi, Y, Song, J, Qi, J, Lu, G, Yan, J, Gao, G.F. | | 登録日 | 2015-11-30 | | 公開日 | 2016-01-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1.
Cell, 164, 2016
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4K66
 | | Structure of an airborne transmissible avian influenza H5 hemagglutinin mutant from the influenza virus A/Indonesia/5/2005 complexed with avian receptor analog LSTa | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | | 著者 | Zhang, W, Shi, Y, Lu, X, Shu, Y, Qi, J, Gao, G.F. | | 登録日 | 2013-04-15 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | | 主引用文献 | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level.
Science, 340, 2013
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3Q2C
 | | Binding properties to HLA class I molecules and the structure of the leukocyte Ig-like receptor A3 (LILRA3/ILT6/LIR4/CD85e) | | 分子名称: | Leukocyte immunoglobulin-like receptor subfamily A member 3 | | 著者 | Ryu, M, Chen, Y, Qi, J.X, Liu, J, Shi, Y, Cheng, H, Gao, G.F. | | 登録日 | 2010-12-20 | | 公開日 | 2011-07-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2: structural evidence
Plos One, 6, 2011
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4K63
 | | Structure of an avian influenza H5 hemagglutinin from the influenza virus complexed with avian receptor analog LSTa | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ... | | 著者 | Zhang, W, Shi, Y, Lu, X, Shu, Y, Qi, J, Gao, G.F. | | 登録日 | 2013-04-15 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level.
Science, 340, 2013
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8HIF
 | | One asymmetric unit of Singapore grouper iridovirus capsid | | 分子名称: | Major capsid protein, Penton protein (VP14), VP137, ... | | 著者 | Zhao, Z.N, Liu, C.C, Zhu, D.J, Qi, J.X, Zhang, X.Z, Gao, G.F. | | 登録日 | 2022-11-20 | | 公開日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Near-atomic architecture of Singapore grouper iridovirus and implications for giant virus assembly.
Nat Commun, 14, 2023
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4LL9
 | | Crystal structure of D3D4 domain of the LILRB1 molecule | | 分子名称: | IODIDE ION, Leukocyte immunoglobulin-like receptor subfamily B member 1 | | 著者 | Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. | | 登録日 | 2013-07-09 | | 公開日 | 2013-09-11 | | 最終更新日 | 2013-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.686 Å) | | 主引用文献 | Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding
Protein Cell, 4, 2013
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1WNC
 | | Crystal structure of the SARS-CoV Spike protein fusion core | | 分子名称: | E2 glycoprotein | | 著者 | Xu, Y, Lou, Z, Liu, Y, Pang, H, Tien, P, Gao, G.F, Rao, Z. | | 登録日 | 2004-07-29 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core
J.Biol.Chem., 279, 2004
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4K62
 | | Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Indonesia/5/2005 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | | 著者 | Zhang, W, Shi, Y, Lu, X, Shu, Y, Qi, J, Gao, G.F. | | 登録日 | 2013-04-15 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | | 主引用文献 | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level.
Science, 340, 2013
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4K64
 | | Structure of an avian influenza H5 hemagglutinin from the influenza virus complexed with human receptor analog LSTc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose | | 著者 | Zhang, W, Shi, Y, Lu, X, Shu, Y, Qi, J, Gao, G.F. | | 登録日 | 2013-04-15 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | | 主引用文献 | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level.
Science, 340, 2013
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3QZW
 | | Plasticity of human CD8 binding to peptide-HLA-A*2402 | | 分子名称: | 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Shi, Y, Qi, J, Gao, G.F. | | 登録日 | 2011-03-07 | | 公開日 | 2011-06-29 | | 最終更新日 | 2013-07-03 | | 実験手法 | X-RAY DIFFRACTION (2.798 Å) | | 主引用文献 | Plasticity of human CD8alpha alpha binding to peptide-HLA-A*2402
Mol.Immunol., 48, 2011
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8GPU
 | | YFV_E_YD6Fab_prefusion | | 分子名称: | Envelope protein, YD6Fab_H, YD6Fab_L | | 著者 | Li, Y, Wu, L, Qi, J, Yan, J, Gao, G.F. | | 登録日 | 2022-08-27 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
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5XLP
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5F18
 | | Structural basis of Ebola virus entry: viral glycoprotein bound to its endosomal receptor Niemann-Pick C1 | | 分子名称: | Niemann-Pick C1 protein | | 著者 | Wang, H, Shi, Y, Song, J, Qi, J, Lu, G, Yan, J, Gao, G.F. | | 登録日 | 2015-11-30 | | 公開日 | 2016-01-20 | | 最終更新日 | 2016-01-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1.
Cell, 164, 2016
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5XJ4
 | | Complex structure of durvalumab-scFv/PD-L1 | | 分子名称: | Programmed cell death 1 ligand 1, durvalumab-VH, durvalumab-VL | | 著者 | Tan, S, Liu, K, Chai, Y, Gao, G.F, Qi, J. | | 登録日 | 2017-04-29 | | 公開日 | 2018-04-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab
Protein Cell, 9, 2018
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4K67
 | | Structure of an airborne transmissible avian influenza H5 hemagglutinin mutant from the influenza virus A/Indonesia/5/2005 complexed with human receptor analog LSTc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, ... | | 著者 | Zhang, W, Shi, Y, Lu, X, Shu, Y, Gao, G.F. | | 登録日 | 2013-04-15 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level.
Science, 340, 2013
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5GYQ
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5H5N
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