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PDB: 1718 件

2HTW
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N4 neuraminidase in complex with DANA
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Neuraminidase
著者Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
1QOW
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Mersacidin from Bacillus
分子名称: MERSACIDIN, METHANOL
著者Schneider, T.R, Kaercher, J, Sheldrick, G.M.
登録日1999-11-19
公開日2000-05-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Ab initio structure determination of the lantibiotic mersacidin.
Acta Crystallogr.,Sect.D, 56, 2000
2HVZ
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Solution structure of the RRM domain of SR rich factor 9G8
分子名称: Splicing factor, arginine/serine-rich 7
著者Tintaru, A.M, Hautbergue, G.M, Golovanov, A.P, Lian, L.Y, Wilson, S.A.
登録日2006-07-31
公開日2006-11-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8.
Embo J., 25, 2006
2HU0
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N1 neuraminidase in complex with oseltamivir 1
分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase
著者Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTY
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N1 neuraminidase
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HU4
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N1 neuraminidase in complex with oseltamivir 2
分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase
著者Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
1PPQ
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NMR structure of 16th module of Immune Adherence Receptor, Cr1 (Cd35)
分子名称: Complement receptor type 1
著者O'Leary, J.M, Bromek, K, Black, G.M, Uhrinova, S, Schmitz, C, Krych, M, Atkinson, J.P, Uhrin, D, Barlow, P.N.
登録日2003-06-17
公開日2004-05-04
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces.
Protein Sci., 13, 2004
2JV3
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Ets-1 PNT domain (29-138) NMR structure ensemble
分子名称: ETS1 proto-oncogene
著者Lee, G.M, Kang, H, Schaerpf, M, Slupsky, C.M, Lawrence, M.P.
登録日2007-09-11
公開日2007-10-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Ets-1 PNT domain (29-138) NMR structure ensemble
To be Published
1QTF
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CRYSTAL STRUCTURE OF EXFOLIATIVE TOXIN B
分子名称: EXFOLIATIVE TOXIN B
著者Vath, G.M, Earhart, C.A, Monie, D.D, Schlievert, P.M, Ohlendorf, D.H.
登録日1999-06-27
公開日1999-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of exfoliative toxin B: a superantigen with enzymatic activity.
Biochemistry, 38, 1999
2JZN
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Solution NMR structure of the productive complex between IIAMannose and IIBMannose of the mannose transporter of the E. coli phosphotransferase system
分子名称: Mannose-specific phosphotransferase enzyme IIA component, Mannose-specific phosphotransferase enzyme IIB component
著者Clore, G.M, Hu, J, Hu, K.
登録日2008-01-10
公開日2008-02-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution NMR Structures of Productive and Non-productive Complexes between the A and B Domains of the Cytoplasmic Subunit of the Mannose Transporter of the Escherichia coli Phosphotransferase System.
J.Biol.Chem., 283, 2008
2LEC
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Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UGGAGU-3'
分子名称: RNA (5'-R(*UP*GP*GP*AP*GP*U)-3'), Serine/arginine-rich splicing factor 2
著者Daubner, G.M, Clery, A, Jayne, S, Stevenin, J, Allain, F.H.-T.
登録日2011-06-15
公開日2011-11-23
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well.
Embo J., 31, 2012
2LEB
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Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UCCAGU-3'
分子名称: RNA (5'-R(*UP*CP*CP*AP*GP*U)-3'), Serine/arginine-rich splicing factor 2
著者Daubner, G.M, Clery, A, Jayne, S, Stevenin, J, Allain, F.H.-T.
登録日2011-06-15
公開日2011-11-23
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well.
Embo J., 31, 2012
2LEA
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Solution structure of human SRSF2 (SC35) RRM
分子名称: Serine/arginine-rich splicing factor 2
著者Daubner, G.M, Clery, A, Jayne, S, Stevenin, J, Allain, F.H.-T.
登録日2011-06-15
公開日2011-11-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well.
Embo J., 31, 2012
1J5K
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COMPLEX OF THE KH3 DOMAIN OF HNRNP K WITH A SINGLE_STRANDED 10MER DNA OLIGONUCLEOTIDE
分子名称: 5'-D(*AP*TP*AP*T*TP*CP*CP*CP*TP*C)-3', Heterogeneous nuclear ribonucleoprotein K
著者Clore, G.M, Braddock, D.T.
登録日2002-05-13
公開日2002-07-10
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA.
EMBO J., 21, 2002
1J6T
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COMPLEX OF ENZYME IIAMTL AND THE HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR FROM ESCHERICHIA COLI NMR, RESTRAINED REGULARIZED MEAN STRUCTURE
分子名称: PHOSPHITE ION, PTS SYSTEM, MANNITOL-SPECIFIC IIABC COMPONENT, ...
著者Clore, G.M, Cornilescu, G.
登録日2002-08-14
公開日2002-11-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of the Phosphoryl Transfer Complex between the Cytoplasmic A Domain of the Mannitol Transporter IImannitol and HPr of the Escherichia coli Phosphotransferase System
J.Biol.Chem., 277, 2002
1J98
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The 1.2 Angstrom Structure of Bacillus subtilis LuxS
分子名称: AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, ZINC ION
著者Ruzheinikov, S.N, Das, S.K, Sedelnikova, S.E, Hartley, A, Foster, S.J, Horsburgh, M.J, Cox, A.G, McCleod, C.W, Mekhalfia, A, Blackburn, G.M, Rice, D.W, Baker, P.J.
登録日2001-05-24
公開日2001-06-06
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The 1.2 A Structure of a Novel Quorum-Sensing Protein, Bacillus subtilis LuxS
J.Mol.Biol., 313, 2001
1IF8
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Carbonic Anhydrase II Complexed With (S)-N-(3-Indol-1-yl-2-methyl-propyl)-4-sulfamoyl-benzamide
分子名称: (S)-N-(3-INDOL-1-YL-2-METHYL-PROPYL)-4-SULFAMOYL-BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
著者Grzybowski, B.A, Ishchenko, A.V, Kim, C.-Y, Topalov, G, Chapman, R, Christianson, D.W, Whitesides, G.M, Shakhnovich, E.I.
登録日2001-04-12
公開日2001-05-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Combinatorial computational method gives new picomolar ligands for a known enzyme.
Proc.Natl.Acad.Sci.USA, 99, 2002
1IE5
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NMR STRUCTURE OF THE THIRD IMMUNOGLOBULIN DOMAIN FROM THE NEURAL CELL ADHESION MOLECULE.
分子名称: NEURAL CELL ADHESION MOLECULE
著者Atkins, A.R, Chung, J, Deechongkit, S, Little, E.B, Edelman, G.M, Wright, P.E, Cunningham, B.A, Dyson, H.J.
登録日2001-04-06
公開日2001-08-08
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding?
J.Mol.Biol., 311, 2001
1J4W
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COMPLEX OF THE KH3 and KH4 DOMAINS OF FBP WITH A SINGLE_STRANDED 29mer DNA OLIGONUCLEOTIDE FROM THE FUSE ELEMENT OF THE C-MYC ONCOGENE
分子名称: DNA (5'-D(*GP*TP*A*TP*AP*TP*TP*CP*CP*CP*TP*CP*GP*GP*G*AP*TP*TP*TP*TP*TP*TP*AP*TP*TP*TP*TP*GP*T)-3'), FUSE binding protein
著者Clore, G.M, Braddock, D.T.
登録日2001-11-30
公開日2002-03-06
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure and dynamics of KH domains from FBP bound to single-stranded DNA.
Nature, 415, 2002
1IHV
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SOLUTION STRUCTURE OF THE DNA BINDING DOMAIN OF HIV-1 INTEGRASE, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: HIV-1 INTEGRASE
著者Clore, G.M, Lodi, P.J, Ernst, J.A, Gronenborn, A.M.
登録日1995-05-12
公開日1996-10-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA binding domain of HIV-1 integrase.
Biochemistry, 34, 1995
1IHW
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SOLUTION STRUCTURE OF THE DNA BINDING DOMAIN OF HIV-1 INTEGRASE, NMR, 40 STRUCTURES
分子名称: HIV-1 INTEGRASE
著者Clore, G.M, Lodi, P.J, Ernst, J.A, Gronenborn, A.M.
登録日1995-05-12
公開日1996-07-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA binding domain of HIV-1 integrase.
Biochemistry, 34, 1995
1IIO
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NMR-Based Structure of the Conserved Protein MTH865 from the Archea Methanobacterium thermoautotrophicum
分子名称: conserved hypothetical protein MTH865
著者Lee, G.M, Edwards, A.M, Arrowsmith, C.H, McIntosh, L.P.
登録日2001-04-23
公開日2001-10-17
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NMR-based structure of the conserved protein MTH865 from the archaeon Methanobacterium thermoautotrophicum.
J.Biomol.NMR, 21, 2001
1IOB
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INTERLEUKIN-1 BETA FROM JOINT X-RAY AND NMR REFINEMENT
分子名称: INTERLEUKIN-1 BETA
著者Shaanan, B, Clore, G.M.
登録日1996-03-14
公開日1996-08-17
最終更新日2024-05-01
実験手法SOLUTION NMR (2 Å), X-RAY DIFFRACTION
主引用文献Combining experimental information from crystal and solution studies: joint X-ray and NMR refinement.
Science, 257, 1992
1HTQ
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Multicopy crystallographic structure of a relaxed glutamine synthetase from Mycobacterium tuberculosis
分子名称: ADENOSINE MONOPHOSPHATE, CITRIC ACID, MANGANESE (II) ION, ...
著者Gill, H.S, Pfluegl, G.M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2001-01-01
公開日2002-07-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Multicopy crystallographic refinement of a relaxed glutamine synthetase from Mycobacterium tuberculosis highlights flexible loops in the enzymatic mechanism and its regulation.
Biochemistry, 41, 2002
1HRY
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THE 3D STRUCTURE OF THE HUMAN SRY-DNA COMPLEX SOLVED BY MULTID-DIMENSIONAL HETERONUCLEAR-EDITED AND-FILTERED NMR
分子名称: DNA (5'-D(*GP*CP*AP*CP*AP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*TP*GP*TP*GP*C)-3'), HUMAN SRY
著者Clore, G.M, Werner, M.H, Huth, J.R, Gronenborn, A.M.
登録日1995-05-09
公開日1995-09-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex.
Cell(Cambridge,Mass.), 81, 1995

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