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PDB: 112 件
2A5T
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Crystal Structure Of The NR1/NR2A ligand-binding cores complex
分子名称: GLUTAMIC ACID, GLYCINE, N-methyl-D-aspartate receptor NMDAR1-4a subunit, ...
著者Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E.
登録日2005-06-30
公開日2005-11-15
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Subunit arrangement and function in NMDA receptors
Nature, 438, 2005
6CNA
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GluN1-GluN2B NMDA receptors with exon 5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Furukawa, H, Grant, T, Grigorieff, N.
登録日2018-03-07
公開日2018-10-03
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Neuron, 98, 2018
1PB7
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CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH GLYCINE AT 1.35 ANGSTROMS RESOLUTION
分子名称: GLYCINE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PB8
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CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-SERINE AT 1.45 ANGSTROMS RESOLUTION
分子名称: D-SERINE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PB9
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CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-CYCLOSERINE AT 1.60 ANGSTROMS RESOLUTION
分子名称: (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PBQ
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CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH 5,7-DICHLOROKYNURENIC ACID (DCKA) AT 1.90 ANGSTROMS RESOLUTION
分子名称: 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-07-29
最終更新日2020-07-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
2A5S
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Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate
分子名称: GLUTAMIC ACID, N-methyl-D-aspartate receptor NMDAR2A subunit
著者Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E.
登録日2005-06-30
公開日2005-11-15
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Subunit arrangement and function in NMDA receptors
Nature, 438, 2005
8USW
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CNQX-bound GluN1a-3A NMDA receptor
分子名称: 7-nitro-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carbonitrile, Glutamate receptor ionotropic, NMDA 1, ...
著者Michalski, K, Furukawa, H.
登録日2023-10-30
公開日2024-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.23 Å)
主引用文献Structure and function of GluN1-3A NMDA receptor excitatory glycine receptor channel.
Sci Adv, 10, 2024
2QTS
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Structure of an acid-sensing ion channel 1 at 1.9 A resolution and low pH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel, CHLORIDE ION, ...
著者Jasti, J, Furukawa, H, Gonzales, E.B, Gouaux, E.
登録日2007-08-02
公開日2007-09-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH
Nature, 449, 2007
6USV
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Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and SDZ 220-040
分子名称: (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, GLYCEROL, GLYCINE, ...
著者Romero-Hernandez, A, Tajima, N, Chou, T, Furukawa, h.
登録日2019-10-28
公開日2020-07-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
8S90
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Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red (C1)
分子名称: Calcium homeostasis modulator protein 1, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2)
著者Syrjanen, J.L, Furukawa, H.
登録日2023-03-27
公開日2023-07-26
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.73 Å)
主引用文献Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red.
Nat Commun, 14, 2023
8S8Z
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Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calcium homeostasis modulator protein 1, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2)
著者Syrjanen, J.L, Furukawa, H.
登録日2023-03-27
公開日2023-07-26
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red.
Nat Commun, 14, 2023
8E96
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Glycine and glutamate bound Human GluN1a-GluN2D NMDA receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, GLYCINE, ...
著者Kang, H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2022-12-14
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
3OEM
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Crystal structure of GluN2D ligand-binding core in complex with N-methyl-D-aspartate
分子名称: Glutamate [NMDA] receptor subunit epsilon-4, N-methyl-D-aspartic acid
著者Simorowski, N, Furukawa, H.
登録日2010-08-12
公開日2011-05-11
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
9ARG
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Rat GluN1-GluN2B NMDA receptor channel in apo conformation
分子名称: Glutamate receptor ionotropic, NMDA 1, NMDA 2B
著者Chou, T.-H, Furukawa, H.
登録日2024-02-23
公開日2024-07-31
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
9ARI
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Rat GluN1-GluN2B NMDA receptor channel in complex with glutamate
分子名称: GLUTAMIC ACID, Glutamate receptor ionotropic, NMDA 2B, ...
著者Chou, T.-H, Furukawa, H.
登録日2024-02-23
公開日2024-07-31
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
9ARE
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Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in open-channel conformation
分子名称: GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2024-02-23
公開日2024-07-31
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
9ARF
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Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in nonactive1 conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Chou, T.-H, Furukawa, H.
登録日2024-02-23
公開日2024-07-31
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
9BIB
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Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in open-channel conformation, C1 symmetry
分子名称: GLUTAMIC ACID, GLYCINE, Glutamate receptor, ...
著者Chou, T.-H, Furukawa, H.
登録日2024-04-23
公開日2024-07-31
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
9ARH
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Rat GluN1-GluN2B NMDA receptor channel in complex with glycine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ...
著者Chou, T.-H, Furukawa, H.
登録日2024-02-23
公開日2024-07-31
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
8E97
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PYD-106-bound Human GluN1a-GluN2C NMDA receptor in splayed conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2022-12-14
実験手法ELECTRON MICROSCOPY (4.19 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E94
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PYD-106-bound Human GluN1a-GluN2C NMDA receptor in intact conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chou, T.-H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2022-12-14
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E93
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D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in splayed conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2022-12-14
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E92
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D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in intact conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2022-12-14
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E99
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Human GluN1a-GluN2A-GluN2C triheteromeric NMDA receptor in complex with Nb-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2022-12-14
実験手法ELECTRON MICROSCOPY (4.24 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022

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件を2024-10-09に公開中

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