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PDB: 101 件
3H5V
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Crystal structure of the GluR2-ATD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2
著者Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E.
登録日2009-04-22
公開日2009-06-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
5TPZ
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Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in apo closed state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 2B, ...
著者Romero-Hernandez, A, Simorwski, N, Karakas, E, Furukawa, H.
登録日2016-10-21
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.095 Å)
主引用文献Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
5TQ0
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Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in the presence of EDTA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB, HEAVY CHAIN, ...
著者Romero-Hernandez, A, Simorowski, N, Karakas, E, Furukawa, H.
登録日2016-10-21
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
5TPW
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Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at the GluN2A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB, HEAVY CHAIN, ...
著者Romero-Hernandez, A, Simorowski, N, Karakas, E, Furukawa, H.
登録日2016-10-21
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.909 Å)
主引用文献Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
6E7R
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Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
5TQ2
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BU of 5tq2 by Molmil
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at GluN1 and GluN2A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB, HEAVY CHAIN, ...
著者Romero-Hernandez, A, Simorowski, N, Karakas, E, Furukawa, H.
登録日2016-10-21
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.289 Å)
主引用文献Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
4NF5
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Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and D-AP5
分子名称: 5-phosphono-D-norvaline, GLYCEROL, GLYCINE, ...
著者Jespersen, A, Tajima, N, Furukawa, H.
登録日2013-10-30
公開日2014-03-12
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
3OEM
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BU of 3oem by Molmil
Crystal structure of GluN2D ligand-binding core in complex with N-methyl-D-aspartate
分子名称: Glutamate [NMDA] receptor subunit epsilon-4, N-methyl-D-aspartic acid
著者Simorowski, N, Furukawa, H.
登録日2010-08-12
公開日2011-05-11
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
3OEL
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Crystal structure of GluN2D ligand-binding core in complex with D-glutamate
分子名称: D-GLUTAMIC ACID, Glutamate [NMDA] receptor subunit epsilon-4
著者Simorowski, N, Furukawa, H.
登録日2010-08-12
公開日2011-05-11
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
3OEN
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Crystal structure of GluN2D ligand-binding core in complex with L-glutamate
分子名称: GLUTAMIC ACID, Glutamate [NMDA] receptor subunit epsilon-4
著者Simorowski, N, Furukawa, H.
登録日2010-08-12
公開日2011-05-11
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
3OEK
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BU of 3oek by Molmil
Crystal structure of GluN2D ligand-binding core in complex with L-aspartate
分子名称: ASPARTIC ACID, Glutamate [NMDA] receptor subunit epsilon-4
著者Simorowski, N, Furukawa, H.
登録日2010-08-12
公開日2011-05-11
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
3H5W
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BU of 3h5w by Molmil
Crystal structure of the GluR2-ATD in space group P212121 without solvent
分子名称: Glutamate receptor 2
著者Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E.
登録日2009-04-22
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.686 Å)
主引用文献Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
6E7W
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BU of 6e7w by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-115
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7S
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Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7U
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Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-31
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7X
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BU of 6e7x by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-97
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7V
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BU of 6e7v by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-88
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7T
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BU of 6e7t by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Regan, M.C, Furukawa, H.
登録日2018-07-27
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
7SAB
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BU of 7sab by Molmil
Phencyclidine-bound GluN1a-GluN2B NMDA receptors
分子名称: 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAD
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BU of 7sad by Molmil
Memantine-bound GluN1a-GluN2B NMDA receptors
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAA
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BU of 7saa by Molmil
Glycine and glutamate bound GluN1a-GluN2B NMDA receptors in non-active 1 conformation at 2.97 Angstrom resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAC
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BU of 7sac by Molmil
S-(+)-ketamine bound GluN1a-GluN2B NMDA receptors at 3.69 Angstrom resolution
分子名称: (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
5U8C
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CRYSTAL STRUCTURE OF GLUN1/GLUN2A LIGAND-BINDING DOMAIN IN COMPLEX WITH GLYCINE AND NVP-AAM077
分子名称: GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2A, GLYCEROL, ...
著者Romero-Hernandez, A, Furukawa, H.
登録日2016-12-14
公開日2017-05-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Novel Mode of Antagonist Binding in NMDA Receptors Revealed by the Crystal Structure of the GluN1-GluN2A Ligand-Binding Domain Complexed to NVP-AAM077.
Mol. Pharmacol., 92, 2017
4NF6
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Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and PPDA
分子名称: (2S,3R)-1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
著者Jespersen, A, Tajima, N, Furukawa, H.
登録日2013-10-30
公開日2014-03-12
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
4NF8
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Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and glutamate in PEG2000MME
分子名称: GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ...
著者Jespersen, A, Tajima, N, Furukawa, H.
登録日2013-10-30
公開日2014-03-12
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (1.856 Å)
主引用文献Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014

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