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PDB: 113 results

7SWW
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BU of 7sww by Molmil
SARS-CoV-2 Spike NTD in complex with neutralizing Fab SARS2-57 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2021-11-21
Release date:2022-11-23
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants
To Be Published
4L5F
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BU of 4l5f by Molmil
Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
Descriptor: Envelope protein, Heavy chain of E106 antibody (VH and CH1 of IgG2c), Light chain of E106 antibody (kappa)
Authors:Edeling, M.A, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-06-11
Release date:2013-12-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
To be Published
2QRI
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BU of 2qri by Molmil
Crystal structure of a single chain trimer composed of the MHC I heavy chain H-2Kb WT, beta-2microglobulin, and ovalbumin-derived peptide.
Descriptor: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
Authors:Mitaksov, V.E, Fremont, D.H.
Deposit date:2007-07-28
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2QRT
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BU of 2qrt by Molmil
Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C, beta-2microglobulin, and ovalbumin-derived peptide.
Descriptor: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
Authors:Mitaksov, V.E, Fremont, D.H.
Deposit date:2007-07-29
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2QRS
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BU of 2qrs by Molmil
Crystal Structure of a single chain trimer composed of the MHC I heavy chain H-2Kb Y84A, beta-2microglobulin, and ovalbumin-derived peptide.
Descriptor: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
Authors:Mitaksov, V.E, Fremont, D.H.
Deposit date:2007-07-29
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2R69
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BU of 2r69 by Molmil
Crystal structure of Fab 1A1D-2 complexed with E-DIII of Dengue virus at 3.8 angstrom resolution
Descriptor: Heavy chain of 1A1D-2, Light chain of 1A1D-2, Major envelope protein E
Authors:Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2007-09-05
Release date:2007-12-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
4E4D
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BU of 4e4d by Molmil
Crystal structure of mouse RANKL-OPG complex
Descriptor: CHLORIDE ION, Tumor necrosis factor ligand superfamily member 11, soluble form, ...
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2012-03-12
Release date:2012-10-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor.
Structure, 20, 2012
4ZLT
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BU of 4zlt by Molmil
Crystal structure of viral chemokine binding protein R17 in complex with CCL3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 3, Putative uncharacterized protein
Authors:Lubman, O.Y, Fremont, D.H.
Deposit date:2015-05-01
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors.
Structure, 24, 2016
4ZKQ
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BU of 4zkq by Molmil
Viral chemokine binding protein R17 encoded by rodent gammaherpesvirus Peru ( RHVP)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Putative uncharacterized protein
Authors:Lubman, O.Y, Fremont, D.H.
Deposit date:2015-04-30
Release date:2015-11-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.898 Å)
Cite:Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors.
Structure, 24, 2016
5ANY
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BU of 5any by Molmil
Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265
Descriptor: E1, E2, FAB, ...
Authors:Fox, J.M, Long, F, Edeling, M.A, Lin, H, Duijl-Richter, M, Fong, R.H, Kahle, K.M, Smit, J.M, Jin, J, Simmons, G, Doranz, B.J, Crowe, J.E, Fremont, D.H, Rossmann, M.G, Diamond, M.S.
Deposit date:2015-09-08
Release date:2015-11-25
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (16.9 Å)
Cite:Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Cell(Cambridge,Mass.), 163, 2015
1XAU
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BU of 1xau by Molmil
STRUCTURE OF THE BTLA ECTODOMAIN
Descriptor: B- and T-lymphocyte attenuator, CADMIUM ION
Authors:Nelson, C.A, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-08-26
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator.
J.Immunol., 180, 2008
4GIQ
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BU of 4giq by Molmil
Crystal Structure of mouse RANK bound to RANKL
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, SODIUM ION, ...
Authors:Nelson, C.A, Wang, M.W.-H, Fremont, D.H.
Deposit date:2012-08-08
Release date:2012-10-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor.
Structure, 20, 2012
4HKJ
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BU of 4hkj by Molmil
Structure of Cowpox CPXV203 in complex with MHCI (H-2Kb)
Descriptor: Beta-2-microglobulin, CPXV203 protein, H-2 class I histocompatibility antigen, ...
Authors:McCoy IV, W.H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-10-15
Release date:2012-11-14
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Mechanism of ER Retrieval of MHC Class I by Cowpox.
Plos Biol., 10, 2012
4FFZ
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BU of 4ffz by Molmil
Crystal Structure of DENV1-E111 fab fragment bound to DENV-1 DIII (Western Pacific-74 strain).
Descriptor: DENV1-E111 fab fragment (heavy chain), DENV1-E111 fab fragment (light chain), Envelope protein E
Authors:Austin, S.K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-06-01
Release date:2012-06-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope.
Plos Pathog., 8, 2012
4FG0
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BU of 4fg0 by Molmil
Structure of the St. Louis Encephalitis Virus envelope protein in the fusogenic trimer conformation.
Descriptor: Polyprotein
Authors:Luca, V.C, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-06-01
Release date:2012-06-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.899 Å)
Cite:Structure of the st. Louis encephalitis virus postfusion envelope trimer.
J.Virol., 87, 2013
8DAN
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BU of 8dan by Molmil
CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein, ...
Authors:Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2022-06-13
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (4.74 Å)
Cite:Alternate domain repeat usage in an alphavirus entry receptor enables host species expansion
To Be Published
8DAQ
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BU of 8daq by Molmil
CryoEM structure of Western equine encephalitis virus VLP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein
Authors:Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2022-06-13
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (4.35 Å)
Cite:Alternate repeat domain usage in an alphavirus entry receptor enables host species expansion
To Be Published
8DWX
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BU of 8dwx by Molmil
Chikungunya VLP in complex with neutralizing Fab 506.C01 (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 506.C01 heavy chain, 506.C01 light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2022-08-02
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8DWW
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BU of 8dww by Molmil
Chikungunya VLP in complex with neutralizing Fab 506.A08 (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 506.A08 heavy chain, 506.A08 light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2022-08-02
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8DWY
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BU of 8dwy by Molmil
Chikungunya VLP in complex with neutralizing Fab CHK-265 (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHK-265 heavy chain, CHK-265 light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2022-08-02
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8SQN
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BU of 8sqn by Molmil
CryoEM structure of Western equine encephalitis virus VLP in complex with the chimeric Du-D1-Mo-D2 MXRA8 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DuD1MoD2 chimeric MXRA8, E1 envelope glycoprotein, ...
Authors:Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2023-05-04
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8.
Cell, 186, 2023
8UFA
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BU of 8ufa by Molmil
Eastern equine encephalitis virus (PE-6) VLP (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 protein, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2023-10-04
Release date:2024-01-17
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
8UFC
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BU of 8ufc by Molmil
Eastern equine encephalitis virus (PE-6) VLP in complex with VLDLR LA(1-2) (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2023-10-04
Release date:2024-01-17
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
8UFB
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BU of 8ufb by Molmil
Eastern equine encephalitis virus (PE-6) VLP in complex with full-length VLDLR (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2023-10-04
Release date:2024-01-17
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
6V4N
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BU of 6v4n by Molmil
Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
Authors:Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-11-28
Release date:2020-10-07
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 53, 2020

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