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PDB: 113 件

7SWW
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BU of 7sww by Molmil
SARS-CoV-2 Spike NTD in complex with neutralizing Fab SARS2-57 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2021-11-21
公開日2022-11-23
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants
To Be Published
4L5F
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BU of 4l5f by Molmil
Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
分子名称: Envelope protein, Heavy chain of E106 antibody (VH and CH1 of IgG2c), Light chain of E106 antibody (kappa)
著者Edeling, M.A, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-06-11
公開日2013-12-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
To be Published
2QRI
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BU of 2qri by Molmil
Crystal structure of a single chain trimer composed of the MHC I heavy chain H-2Kb WT, beta-2microglobulin, and ovalbumin-derived peptide.
分子名称: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
著者Mitaksov, V.E, Fremont, D.H.
登録日2007-07-28
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2QRT
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BU of 2qrt by Molmil
Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C, beta-2microglobulin, and ovalbumin-derived peptide.
分子名称: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
著者Mitaksov, V.E, Fremont, D.H.
登録日2007-07-29
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2QRS
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BU of 2qrs by Molmil
Crystal Structure of a single chain trimer composed of the MHC I heavy chain H-2Kb Y84A, beta-2microglobulin, and ovalbumin-derived peptide.
分子名称: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
著者Mitaksov, V.E, Fremont, D.H.
登録日2007-07-29
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2R69
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BU of 2r69 by Molmil
Crystal structure of Fab 1A1D-2 complexed with E-DIII of Dengue virus at 3.8 angstrom resolution
分子名称: Heavy chain of 1A1D-2, Light chain of 1A1D-2, Major envelope protein E
著者Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G.
登録日2007-09-05
公開日2007-12-25
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
4E4D
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BU of 4e4d by Molmil
Crystal structure of mouse RANKL-OPG complex
分子名称: CHLORIDE ION, Tumor necrosis factor ligand superfamily member 11, soluble form, ...
著者Nelson, C.A, Fremont, D.H.
登録日2012-03-12
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor.
Structure, 20, 2012
4ZLT
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BU of 4zlt by Molmil
Crystal structure of viral chemokine binding protein R17 in complex with CCL3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 3, Putative uncharacterized protein
著者Lubman, O.Y, Fremont, D.H.
登録日2015-05-01
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors.
Structure, 24, 2016
4ZKQ
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BU of 4zkq by Molmil
Viral chemokine binding protein R17 encoded by rodent gammaherpesvirus Peru ( RHVP)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Putative uncharacterized protein
著者Lubman, O.Y, Fremont, D.H.
登録日2015-04-30
公開日2015-11-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors.
Structure, 24, 2016
5ANY
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BU of 5any by Molmil
Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265
分子名称: E1, E2, FAB, ...
著者Fox, J.M, Long, F, Edeling, M.A, Lin, H, Duijl-Richter, M, Fong, R.H, Kahle, K.M, Smit, J.M, Jin, J, Simmons, G, Doranz, B.J, Crowe, J.E, Fremont, D.H, Rossmann, M.G, Diamond, M.S.
登録日2015-09-08
公開日2015-11-25
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (16.9 Å)
主引用文献Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Cell(Cambridge,Mass.), 163, 2015
1XAU
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BU of 1xau by Molmil
STRUCTURE OF THE BTLA ECTODOMAIN
分子名称: B- and T-lymphocyte attenuator, CADMIUM ION
著者Nelson, C.A, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
登録日2004-08-26
公開日2004-10-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator.
J.Immunol., 180, 2008
4GIQ
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BU of 4giq by Molmil
Crystal Structure of mouse RANK bound to RANKL
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, SODIUM ION, ...
著者Nelson, C.A, Wang, M.W.-H, Fremont, D.H.
登録日2012-08-08
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor.
Structure, 20, 2012
4HKJ
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BU of 4hkj by Molmil
Structure of Cowpox CPXV203 in complex with MHCI (H-2Kb)
分子名称: Beta-2-microglobulin, CPXV203 protein, H-2 class I histocompatibility antigen, ...
著者McCoy IV, W.H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-10-15
公開日2012-11-14
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Mechanism of ER Retrieval of MHC Class I by Cowpox.
Plos Biol., 10, 2012
4FFZ
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BU of 4ffz by Molmil
Crystal Structure of DENV1-E111 fab fragment bound to DENV-1 DIII (Western Pacific-74 strain).
分子名称: DENV1-E111 fab fragment (heavy chain), DENV1-E111 fab fragment (light chain), Envelope protein E
著者Austin, S.K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-06-01
公開日2012-06-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope.
Plos Pathog., 8, 2012
4FG0
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BU of 4fg0 by Molmil
Structure of the St. Louis Encephalitis Virus envelope protein in the fusogenic trimer conformation.
分子名称: Polyprotein
著者Luca, V.C, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-06-01
公開日2012-06-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.899 Å)
主引用文献Structure of the st. Louis encephalitis virus postfusion envelope trimer.
J.Virol., 87, 2013
8DAN
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BU of 8dan by Molmil
CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein, ...
著者Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2022-06-13
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (4.74 Å)
主引用文献Alternate domain repeat usage in an alphavirus entry receptor enables host species expansion
To Be Published
8DAQ
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BU of 8daq by Molmil
CryoEM structure of Western equine encephalitis virus VLP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein
著者Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2022-06-13
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (4.35 Å)
主引用文献Alternate repeat domain usage in an alphavirus entry receptor enables host species expansion
To Be Published
8DWX
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BU of 8dwx by Molmil
Chikungunya VLP in complex with neutralizing Fab 506.C01 (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 506.C01 heavy chain, 506.C01 light chain, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2022-08-02
公開日2023-05-31
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8DWW
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BU of 8dww by Molmil
Chikungunya VLP in complex with neutralizing Fab 506.A08 (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 506.A08 heavy chain, 506.A08 light chain, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2022-08-02
公開日2023-05-31
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8DWY
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BU of 8dwy by Molmil
Chikungunya VLP in complex with neutralizing Fab CHK-265 (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHK-265 heavy chain, CHK-265 light chain, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2022-08-02
公開日2023-05-31
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8SQN
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BU of 8sqn by Molmil
CryoEM structure of Western equine encephalitis virus VLP in complex with the chimeric Du-D1-Mo-D2 MXRA8 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DuD1MoD2 chimeric MXRA8, E1 envelope glycoprotein, ...
著者Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2023-05-04
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8.
Cell, 186, 2023
8UFA
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BU of 8ufa by Molmil
Eastern equine encephalitis virus (PE-6) VLP (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 protein, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
登録日2023-10-04
公開日2024-01-17
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
8UFC
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BU of 8ufc by Molmil
Eastern equine encephalitis virus (PE-6) VLP in complex with VLDLR LA(1-2) (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
登録日2023-10-04
公開日2024-01-17
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
8UFB
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BU of 8ufb by Molmil
Eastern equine encephalitis virus (PE-6) VLP in complex with full-length VLDLR (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
登録日2023-10-04
公開日2024-01-17
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
6V4N
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BU of 6v4n by Molmil
Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
著者Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-11-28
公開日2020-10-07
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 53, 2020

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件を2024-06-12に公開中

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