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PDB: 350 件

3ZJD
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A20 OTU domain in reduced, active state at 1.87 A resolution
分子名称: 1,2-ETHANEDIOL, A20P50, CHLORIDE ION
著者Kulathu, Y, Garcia, F.J, Mevissen, T.E.T, Busch, M, Arnaudo, N, Carroll, K.S, Barford, D, Komander, D.
登録日2013-01-17
公開日2013-03-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation
Nat.Commun., 4, 2013
2IZY
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BU of 2izy by Molmil
Molecular Basis of AKAP Specificity for PKA Regulatory Subunits
分子名称: CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT II
著者Gold, M.G, Lygren, B, Dokurno, P, Hoshi, N, McConnachie, G, Tasken, K, Carlson, C.R, Scott, J.D, Barford, D.
登録日2006-07-27
公開日2006-11-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular Basis of Akap Specificity for Pka Regululatory Subunits
Mol.Cell, 24, 2006
4ADY
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BU of 4ady by Molmil
Crystal structure of 26S proteasome subunit Rpn2
分子名称: 26S PROTEASOME REGULATORY SUBUNIT RPN2
著者Kulkarni, K, He, J, Da Fonseca, P.C.A, Krutauz, D, Glickman, M.H, Barford, D, Morris, E.P.
登録日2012-01-04
公開日2012-03-14
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Structure of the 26S Proteasome Subunit Rpn2 Reveals its Pc Repeat Domain as a Closed Toroid of Two Concentric Alpha-Helical Rings
Structure, 20, 2012
4AEZ
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Crystal Structure of Mitotic Checkpoint Complex
分子名称: MITOTIC SPINDLE CHECKPOINT COMPONENT MAD2, MITOTIC SPINDLE CHECKPOINT COMPONENT MAD3, WD REPEAT-CONTAINING PROTEIN SLP1
著者Kulkarni, K.A, Chao, W.C.H, Zhang, Z, Barford, D.
登録日2012-01-13
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Mitotic Checkpoint Complex
Nature, 484, 2012
4BH6
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Insights into degron recognition by APC coactivators from the structure of an Acm1-Cdh1 complex
分子名称: APC/C ACTIVATOR PROTEIN CDH1, APC/C-CDH1 MODULATOR 1
著者He, J, Chao, W.C.H, Zhang, Z, Yang, J, Cronin, N, Barford, D.
登録日2013-03-29
公開日2013-06-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights Into Degron Recognition by Apc/C Coactivators from the Structure of an Acm1-Cdh1 Complex.
Mol.Cell, 50, 2013
4BLP
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BU of 4blp by Molmil
P4 PROTEIN FROM BACTERIOPHAGE PHI13
分子名称: CITRATE ANION, GLYCEROL, PACKAGING ENZYME P4
著者El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J.
登録日2013-05-04
公開日2013-08-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution.
Nucleic Acids Res., 41, 2013
4A8F
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Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*DAP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
4BWY
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BU of 4bwy by Molmil
P4 PROTEIN FROM BACTERIOPHAGE PHI8 (R32)
分子名称: P4
著者El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J.
登録日2013-07-05
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution.
Nucleic Acids Res., 41, 2013
4A8W
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BU of 4a8w by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
2XPI
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BU of 2xpi by Molmil
Crystal structure of APC/C hetero-tetramer Cut9-Hcn1
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT CUT9, ANAPHASE-PROMOTING COMPLEX SUBUNIT HCN1 HCN1/CDC26,20S CYCLOSOME/APC COMPLEX PROTEIN HCN1, CHAPERONE-LIKE PROTEIN HCN1, ...
著者Zhang, Z, Kulkarni, K.A, Barford, D.
登録日2010-08-26
公開日2011-03-30
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Apc/C Subunit Cdc16/Cut9 is a Contiguous Tetratricopeptide Superhelix with a Homo-Dimer Interface Similar to Cdc27
Embo J., 29, 2010
4A8K
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Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*AP*AP*TP*CP)-3', 5'-D(*TP*CP)-3', GUANOSINE-5'-TRIPHOSPHATE, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
4A8M
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BU of 4a8m by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*AP*AP*TP*CP)-3', ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
4A8Q
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Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*DTP*TP*CP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
2YIN
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BU of 2yin by Molmil
STRUCTURE OF THE COMPLEX BETWEEN Dock2 AND Rac1.
分子名称: DEDICATOR OF CYTOKINESIS PROTEIN 2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1
著者Kulkarni, K.A, Yang, J, Zhang, Z, Barford, D.
登録日2011-05-16
公開日2011-05-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (Dock) Nucleotide Exchange Factors.
J.Biol.Chem., 286, 2011
4A8S
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BU of 4a8s by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*TP*TP*TP*TP*CP*GP*CP*GP*TP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
1HI1
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BU of 1hi1 by Molmil
RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN
著者Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I.
登録日2001-01-01
公開日2001-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
2YI9
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BU of 2yi9 by Molmil
Structure of the RNA polymerase VP1 from Infectious Pancreatic Necrosis Virus in complex with magnesium
分子名称: CHLORIDE ION, MAGNESIUM ION, POTASSIUM ION, ...
著者Graham, S.C, Sarin, L.P, Bahar, M.W, Myers, R.A, Stuart, D.I, Bamford, D.H, Grimes, J.M.
登録日2011-05-11
公開日2011-07-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The N-Terminus of the RNA Polymerase from Infectious Pancreatic Necrosis Virus is the Determinant of Genome Attachment.
Plos Pathog., 7, 2011
4BLQ
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BU of 4blq by Molmil
P4 PROTEIN FROM BACTERIOPHAGE PHI8
分子名称: P4
著者El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J.
登録日2013-05-04
公開日2013-08-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution.
Nucleic Acids Res., 41, 2013
5A31
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BU of 5a31 by Molmil
Structure of the human APC-Cdh1-Hsl1-UbcH10 complex.
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Chang, L, Zhang, Z, Yang, J, Mclaughlin, S.H, Barford, D.
登録日2015-05-26
公開日2015-11-18
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Atomic Structure of the Apc/C and its Mechanism of Protein Ubiquitination.
Nature, 522, 2015
2B4S
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BU of 2b4s by Molmil
Crystal structure of a complex between PTP1B and the insulin receptor tyrosine kinase
分子名称: Insulin receptor, SULFATE ION, Tyrosine-protein phosphatase, ...
著者Li, S, Depetris, R.S, Barford, D, Chernoff, J, Hubbard, S.R.
登録日2005-09-26
公開日2005-11-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of a Complex between Protein Tyrosine Phosphatase 1B and the Insulin Receptor Tyrosine Kinase.
Structure, 13, 2005
4A8Y
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BU of 4a8y by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*TP*TP*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
5BPZ
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BU of 5bpz by Molmil
Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain
分子名称: 1,2-ETHANEDIOL, Anapc5 protein
著者Cronin, N, Yang, J, Zhang, Z, Barford, D.
登録日2015-05-28
公開日2015-09-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain.
J.Mol.Biol., 427, 2015
5BPT
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Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain
分子名称: MGC81278 protein
著者Cronin, N, Yang, J, Zhang, Z, Barford, D.
登録日2015-05-28
公開日2015-09-02
最終更新日2015-10-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain.
J.Mol.Biol., 427, 2015
7FRT
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BU of 7frt by Molmil
PanDDA analysis group deposition of ground-state model of PTP1B, using pre-clustering, cluster 1
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
著者Mehlman, T, Biel, J, Azeem, S.M, Nelson, E.R, Hossain, S, Dunnett, L.E, Paterson, N.G, Douangamath, A, Talon, R, Axford, D, Orins, H, von Delft, F, Keedy, D.A.
登録日2022-10-26
公開日2022-11-23
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B.
Elife, 12, 2023
7FRU
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PanDDA analysis group deposition of ground-state model of PTP1B, using pre-clustering, cluster 2
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
著者Mehlman, T, Biel, J, Azeem, S.M, Nelson, E.R, Hossain, S, Dunnett, L.E, Paterson, N.G, Douangamath, A, Talon, R, Axford, D, Orins, H, von Delft, F, Keedy, D.A.
登録日2022-10-26
公開日2022-11-23
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B.
Elife, 12, 2023

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