5U5P
 
 | | Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus Musculus Complexed with a MLH1 NLS Peptide | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA mismatch repair protein Mlh1, Importin subunit alpha-1 | | 著者 | Barros, A.C, Takeda, A.A, Dreyer, T.R, Velazquez-Campoy, A, Kobe, B, Fontes, M.R. | | 登録日 | 2016-12-07 | | 公開日 | 2018-03-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.171 Å) | | 主引用文献 | DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway.
Biochimie, 146, 2018
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2Q2J
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3UVU
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5U5R
 | | Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a PMS2 NLS Peptide | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Mismatch repair endonuclease PMS2 | | 著者 | Barros, A.C, Takeda, A.A, Dreyer, T.R, Velazquez-Campoy, A, Kobe, B, Fontes, M.R. | | 登録日 | 2016-12-07 | | 公開日 | 2018-03-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway.
Biochimie, 146, 2018
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3L3Q
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3IQ3
 | | Crystal Structure of Bothropstoxin-I complexed with polietilene glicol 4000 - crystallized at 283 K | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Phospholipase A2 homolog bothropstoxin-1, SULFATE ION | | 著者 | Salvador, G.H.M, Marchi-Salvador, D.P, Silva, M.C.O, Soares, A.M, Fontes, M.R.M. | | 登録日 | 2009-08-19 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
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1PC9
 | | Crystal Structure of BnSP-6, a Lys49-Phospholipase A2 | | 分子名称: | BnSP-6 | | 著者 | Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R.M. | | 登録日 | 2003-05-16 | | 公開日 | 2004-06-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights.
Biochem.Biophys.Res.Commun., 311, 2003
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1U73
 | | Crystal structure of a Dimeric Acidic Platelet Aggregation Inhibitor and Hypotensive Phospholipase A2 from Bothrops jararacussu | | 分子名称: | hypotensive phospholipase A2 | | 著者 | Magro, A.J, Murakami, M.T, Soares, A.M, Arni, R.K, Fontes, M.R. | | 登録日 | 2004-08-02 | | 公開日 | 2004-10-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of an acidic platelet aggregation inhibitor and hypotensive phospholipase A(2) in the monomeric and dimeric states: insights into its oligomeric state
Biochem.Biophys.Res.Commun., 323, 2004
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3HZD
 | | Crystal structure of bothropstoxin-I (BthTX-I), a PLA2 homologue from Bothrops jararacussu venom | | 分子名称: | LITHIUM ION, Phospholipase A2 homolog bothropstoxin-1 | | 著者 | Silva, M.C.O, Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.M. | | 登録日 | 2009-06-23 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
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3I3I
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3I03
 | | Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB) - monomeric form at a high resolution | | 分子名称: | ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide | | 著者 | Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.M. | | 登録日 | 2009-06-24 | | 公開日 | 2010-05-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
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3T0R
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3HZW
 | | Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB) | | 分子名称: | ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide | | 著者 | Fernandes, C.A.H, Marchi-Salvador, D.P, Soares, A.M, Fontes, M.R.M. | | 登録日 | 2009-06-24 | | 公開日 | 2010-05-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
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1IQ1
 | | CRYSTAL STRUCTURE OF THE IMPORTIN-ALPHA(44-54)-IMPORTIN-ALPHA(70-529) COMPLEX | | 分子名称: | IMPORTIN ALPHA-2 SUBUNIT | | 著者 | Catimel, B, Teh, T, Fontes, M.R.M, Jennings, I.G, Kobe, B. | | 登録日 | 2001-05-28 | | 公開日 | 2001-11-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Biophysical characterization of interactions involving importin-alpha during nuclear import.
J.Biol.Chem., 276, 2001
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2QOG
 | | Crotoxin B, the basic PLA2 from Crotalus durissus terrificus. | | 分子名称: | CALCIUM ION, Phospholipase A2 CB1, Phospholipase A2 CB2 | | 著者 | Marchi-Salvador, D.P, Correa, L.C, Fontes, M.R.M. | | 登録日 | 2007-07-20 | | 公開日 | 2008-04-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Insights into the role of oligomeric state on the biological activities of crotoxin: crystal structure of a tetrameric phospholipase A2 formed by two isoforms of crotoxin B from Crotalus durissus terrificus venom.
Proteins, 72, 2008
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2OQD
 | | Crystal Structure of BthTX-II | | 分子名称: | Phospholipase A2 | | 著者 | Correa, L.C, Marchi-Salvador, D.P, Cintra, A.C.O, Soares, A.M, Fontes, M.R.M. | | 登録日 | 2007-01-31 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Crystal structure of a myotoxic Asp49-phospholipase A(2) with low catalytic activity: Insights into Ca(2+)-independent catalytic mechanism.
Biochim.Biophys.Acta, 1784, 2008
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6B81
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6B83
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6B84
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6B80
 | | Crystal structure of myotoxin II from Bothrops moojeni complexed to myristic acid | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Basic phospholipase A2 homolog 2, MYRISTIC ACID, ... | | 著者 | Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M. | | 登録日 | 2017-10-05 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | | 主引用文献 | Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin.
Biochim Biophys Acta Proteins Proteom, 1866, 2018
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1GOD
 | | MONOMERIC LYS-49 PHOSPHOLIPASE A2 HOMOLOGUE ISOLATED FROM THE VENOM OF CERROPHIDION (BOTHROPS) GODMANI | | 分子名称: | PROTEIN (PHOSPHOLIPASE A2) | | 著者 | Arni, R.K, Fontes, M.R.M, Barberato, C, Gutierrez, J.M, Diaz-Oreiro, C, Ward, R.J. | | 登録日 | 1999-04-16 | | 公開日 | 1999-04-23 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of myotoxin II, a monomeric Lys49-phospholipase A2 homologue isolated from the venom of Cerrophidion (Bothrops) godmani.
Arch.Biochem.Biophys., 366, 1999
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3I3H
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1HOR
 | | STRUCTURE AND CATALYTIC MECHANISM OF GLUCOSAMINE 6-PHOSPHATE DEAMINASE FROM ESCHERICHIA COLI AT 2.1 ANGSTROMS RESOLUTION | | 分子名称: | 2-DEOXY-2-AMINO GLUCITOL-6-PHOSPHATE, GLUCOSAMINE 6-PHOSPHATE DEAMINASE, PHOSPHATE ION | | 著者 | Oliva, G, Fontes, M.R.M, Garratt, R.C, Altamirano, M.M, Calcagno, M.L, Horjales, E. | | 登録日 | 1995-09-13 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 A resolution.
Structure, 3, 1995
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4YV5
 | | Crystal Structure of Myotoxin II from Bothrops moojeni complexed to Suramin | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Basic phospholipase A2 homolog 2, ... | | 著者 | Salvador, G.H.M, Fontes, M.R.M. | | 登録日 | 2015-03-19 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional evidence for membrane docking and disruption sites on phospholipase A2-like proteins revealed by complexation with the inhibitor suramin.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4YZ7
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