4YV5

Crystal Structure of Myotoxin II from Bothrops moojeni complexed to Suramin

Summary for 4YV5

• Entry DOI: 10.2210/pdb4yv5/pdb
• Related: 4KF3
• Descriptor: Basic phospholipase A2 homolog 2, SULFATE ION, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... (6 entities in total)
• Functional Keywords: bothrops moojeni, myotoxin ii, lys49-pla2, suramin, toxin
• Biological source: Bothrops moojeni (Lance-headed viper)
• Cellular location: Secreted: Q9I834
• Total number of polymer chains: 2
• Total formula weight: 31922.42

Authors

Salvador, G.H.M.,Fontes, M.R.M. (deposition date: 2015-03-19, release date: 2015-10-14, Last modification date: 2023-09-27)

• Primary citation: Salvador, G.H.,Dreyer, T.R.,Cavalcante, W.L.,Matioli, F.F.,Dos Santos, J.I.,Velazquez-Campoy, A.,Gallacci, M.,Fontes, M.R.; Structural and functional evidence for membrane docking and disruption sites on phospholipase A2-like proteins revealed by complexation with the inhibitor suramin.; Acta Crystallogr. D Biol. Crystallogr., 71:2066-2078, 2015; PubMed: 26457430; DOI: 10.1107/S1399004715014443

Experimental method

X-RAY DIFFRACTION (1.9 Å)