1M05
 
 | | HLA B8 in complex with an Epstein Barr Virus determinant | | 分子名称: | Beta-2-microglobulin, CADMIUM ION, EBNA-3 nuclear protein, ... | | 著者 | Kjer-Nielsen, L, Clements, C.S, Brooks, A.G, Purcell, A.W, Fontes, M.R, McCluskey, J, Rossjohn, J. | | 登録日 | 2002-06-11 | | 公開日 | 2003-09-02 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and
a mode of MHC class I dimerization.
J.IMMUNOL., 169, 2003
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6MQF
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6MQD
 | | Myotoxin II from Bothrops moojeni complexed with Rosmarinic Acid | | 分子名称: | (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, Basic phospholipase A2 homolog 2 | | 著者 | Salvador, G.H.M, Fontes, M.R.M. | | 登録日 | 2018-10-09 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A2-like proteins using functional, structural and bioinformatics approaches.
Sci Rep, 9, 2019
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3UVU
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3JR8
 | | Crystal Structure of BthTX-II (Asp49-PLA2 from Bothrops jararacussu snake venom) with calcium ions | | 分子名称: | CALCIUM ION, Phospholipase A2 bothropstoxin-2 | | 著者 | Borges, R.J, dos Santos, J.I, Fontes, M.R.M. | | 登録日 | 2009-09-08 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A2 class.
Proteins, 79, 2011
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3QNL
 | | Crystal structure of PrTX-I complexed to Rosmarinic Acid | | 分子名称: | (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ISOPROPYL ALCOHOL, ... | | 著者 | dos Santos, J.I, Fontes, M.R.M. | | 登録日 | 2011-02-08 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition.
Plos One, 6, 2011
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3RZX
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3RZ9
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2OK9
 | | PrTX-I-BPB | | 分子名称: | ISOPROPYL ALCOHOL, Phospholipase A2 homolog 1, p-Bromophenacyl bromide | | 著者 | Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R. | | 登録日 | 2007-01-16 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Crystal structure of a phospholipase A(2) homolog complexed with p-bromophenacyl bromide reveals important structural changes associated with the inhibition of myotoxic activity.
Biochim.Biophys.Acta, 1794, 2009
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2QOG
 | | Crotoxin B, the basic PLA2 from Crotalus durissus terrificus. | | 分子名称: | CALCIUM ION, Phospholipase A2 CB1, Phospholipase A2 CB2 | | 著者 | Marchi-Salvador, D.P, Correa, L.C, Fontes, M.R.M. | | 登録日 | 2007-07-20 | | 公開日 | 2008-04-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Insights into the role of oligomeric state on the biological activities of crotoxin: crystal structure of a tetrameric phospholipase A2 formed by two isoforms of crotoxin B from Crotalus durissus terrificus venom.
Proteins, 72, 2008
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1Z76
 | | Crystal structure of an acidic phospholipase A2 (BthA-I) from Bothrops jararacussu venom complexed with p-bromophenacyl bromide | | 分子名称: | p-Bromophenacyl bromide, phospholipase A2 | | 著者 | Magro, A.J, Takeda, A.A, Soares, A.M, Fontes, M.R. | | 登録日 | 2005-03-24 | | 公開日 | 2006-03-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure of BthA-I complexed with p-bromophenacyl bromide: possible correlations with lack of pharmacological activity.
Acta Crystallogr.,Sect.D, 61, 2005
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7M60
 | | Structure of Mouse Importin alpha MLH1-S467A NLS Peptide Complex | | 分子名称: | DNA mismatch repair protein Mlh1 NLS peptide, Importin subunit alpha-1 | | 著者 | De Oliveira, H.C, Da Silva, T.D, Fukuda, C.A, Fontes, M.R.M. | | 登録日 | 2021-03-25 | | 公開日 | 2021-07-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
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7LYE
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1XXS
 | | Structural insights for fatty acid binding in a Lys49 phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid | | 分子名称: | Phospholipase A2 homolog 2, STEARIC ACID, SULFATE ION | | 著者 | Watanabe, L, Soares, A.M, Ward, R.J, Fontes, M.R, Arni, R.K. | | 登録日 | 2004-11-08 | | 公開日 | 2005-03-29 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights for fatty acid binding in a Lys49-phospholipase A(2): crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid
Biochimie, 87, 2005
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4KF3
 | | Crystal Structure of Myotoxin II (MjTX-II), a myotoxic Lys49-phospholipase A2 from Bothrops moojeni. | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Basic phospholipase A2 homolog 2, ISOPROPYL ALCOHOL | | 著者 | Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M. | | 登録日 | 2013-04-26 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structural and functional studies with mytoxin II from Bothrops moojeni reveal remarkable similarities and differences compared to other catalytically inactive phospholipases A2-like.
Toxicon, 72C, 2013
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2OQD
 | | Crystal Structure of BthTX-II | | 分子名称: | Phospholipase A2 | | 著者 | Correa, L.C, Marchi-Salvador, D.P, Cintra, A.C.O, Soares, A.M, Fontes, M.R.M. | | 登録日 | 2007-01-31 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Crystal structure of a myotoxic Asp49-phospholipase A(2) with low catalytic activity: Insights into Ca(2+)-independent catalytic mechanism.
Biochim.Biophys.Acta, 1784, 2008
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1IQ1
 | | CRYSTAL STRUCTURE OF THE IMPORTIN-ALPHA(44-54)-IMPORTIN-ALPHA(70-529) COMPLEX | | 分子名称: | IMPORTIN ALPHA-2 SUBUNIT | | 著者 | Catimel, B, Teh, T, Fontes, M.R.M, Jennings, I.G, Kobe, B. | | 登録日 | 2001-05-28 | | 公開日 | 2001-11-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Biophysical characterization of interactions involving importin-alpha during nuclear import.
J.Biol.Chem., 276, 2001
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6WBA
 | | Structure of Mouse Importin alpha MLH1- R470A NLS Peptide Complex | | 分子名称: | DNA mismatch repair protein Mlh1, Importin subunit alpha-1 | | 著者 | de Barros, A.C, da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M. | | 登録日 | 2020-03-26 | | 公開日 | 2021-07-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | | 主引用文献 | Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
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6WBB
 | | Structure of Mouse Importin alpha - MLH1-E475A NLS peptide complex | | 分子名称: | DNA mismatch repair protein Mlh1, Importin subunit alpha-1 | | 著者 | De Barros, A.C, Da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M. | | 登録日 | 2020-03-26 | | 公開日 | 2021-07-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.663 Å) | | 主引用文献 | Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
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6WBC
 | | Structure of Mouse Importin alpha- MLH1-R472K NLS Peptide Complex | | 分子名称: | DNA mismatch repair protein Mlh1, Importin subunit alpha-1 | | 著者 | de Barros, A.C, da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M. | | 登録日 | 2020-03-26 | | 公開日 | 2021-07-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
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3T0R
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1DEA
 | | STRUCTURE AND CATALYTIC MECHANISM OF GLUCOSAMINE 6-PHOSPHATE DEAMINASE FROM ESCHERICHIA COLI AT 2.1 ANGSTROMS RESOLUTION | | 分子名称: | GLUCOSAMINE 6-PHOSPHATE DEAMINASE, PHOSPHATE ION | | 著者 | Oliva, G, Fontes, M.R.M, Garratt, R.C, Altamirano, M.M, Calcagno, M.L, Horjales, E. | | 登録日 | 1995-09-13 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 A resolution.
Structure, 3, 1995
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3L3Q
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3IQ3
 | | Crystal Structure of Bothropstoxin-I complexed with polietilene glicol 4000 - crystallized at 283 K | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Phospholipase A2 homolog bothropstoxin-1, SULFATE ION | | 著者 | Salvador, G.H.M, Marchi-Salvador, D.P, Silva, M.C.O, Soares, A.M, Fontes, M.R.M. | | 登録日 | 2009-08-19 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
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1PC9
 | | Crystal Structure of BnSP-6, a Lys49-Phospholipase A2 | | 分子名称: | BnSP-6 | | 著者 | Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R.M. | | 登録日 | 2003-05-16 | | 公開日 | 2004-06-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights.
Biochem.Biophys.Res.Commun., 311, 2003
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