7ZMX
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![BU of 7zmx by Molmil](/molmil-images/mine/7zmx) | |
6QWP
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![BU of 6qwp by Molmil](/molmil-images/mine/6qwp) | Crystal structure of T7 bacteriophage portal protein, 13mer, closed valve | Descriptor: | Portal protein | Authors: | Fabrega-Ferrer, M, Cuervo, A, Machon, C, Fernandez, F.J, Perez-Luque, R, Pous, J, Vega, M.C, Carrascosa, J.L, Coll, M. | Deposit date: | 2019-03-06 | Release date: | 2019-09-04 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism. Nat Commun, 10, 2019
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6QX5
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![BU of 6qx5 by Molmil](/molmil-images/mine/6qx5) | Crystal structure of T7 bacteriophage portal protein, 12mer, closed valve | Descriptor: | Portal protein | Authors: | Fabrega-Ferrer, M, Cuervo, A, Machon, C, Fernandez, F.J, Perez-Luque, R, Pous, J, Vega, M.C, Carrascosa, J.L, Coll, M. | Deposit date: | 2019-03-07 | Release date: | 2019-09-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism. Nat Commun, 10, 2019
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6R21
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![BU of 6r21 by Molmil](/molmil-images/mine/6r21) | Cryo-EM structure of T7 bacteriophage fiberless tail complex | Descriptor: | Portal protein, Tail tubular protein gp11, Tail tubular protein gp12 | Authors: | Cuervo, A, Fabrega-Ferrer, M, Machon, C, Conesa, J.J, Perez-Ruiz, M, Coll, M, Carrascosa, J.L. | Deposit date: | 2019-03-15 | Release date: | 2019-09-04 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism. Nat Commun, 10, 2019
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6QXM
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![BU of 6qxm by Molmil](/molmil-images/mine/6qxm) | Cryo-EM structure of T7 bacteriophage portal protein, 12mer, open valve | Descriptor: | Portal protein | Authors: | Fabrega-Ferrer, M, Cuervo, A, Machon, C, Fernandez, F.J, Perez-Luque, R, Pous, J, Vega, M.C, Carrascosa, J.L, Coll, M. | Deposit date: | 2019-03-07 | Release date: | 2019-09-04 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism. Nat Commun, 10, 2019
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7P35
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![BU of 7p35 by Molmil](/molmil-images/mine/7p35) | Structure of the SARS-CoV-2 3CL protease in complex with rupintrivir | Descriptor: | 3C-like proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | Authors: | Fabrega-Ferrer, M, Perez-Saavedra, J, Herrera-Morande, A, Coll, M. | Deposit date: | 2021-07-07 | Release date: | 2021-07-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.256 Å) | Cite: | Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404. Antiviral Res., 208, 2022
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4I3F
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![BU of 4i3f by Molmil](/molmil-images/mine/4i3f) | Crystal structure of serine hydrolase CCSP0084 from the polyaromatic hydrocarbon (PAH)-degrading bacterium Cycloclasticus zankles | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | Authors: | Stogios, P.J, Xu, X, Dong, A, Cui, H, Alcaide, M, Tornes, J, Gertler, C, Yakimov, M.M, Golyshin, P.N, Ferrer, M, Savchenko, A. | Deposit date: | 2012-11-26 | Release date: | 2013-06-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Single residues dictate the co-evolution of dual esterases: MCP hydrolases from the alpha / beta hydrolase family. Biochem.J., 454, 2013
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6TJP
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![BU of 6tjp by Molmil](/molmil-images/mine/6tjp) | Crystal structure of T7 bacteriophage portal protein, 13mer, closed valve - P212121 | Descriptor: | Portal protein | Authors: | Fabrega-Ferrer, M, Cuervo, A, Fernandez, F.J, Machon, C, Perez-Luque, R, Pous, J, Vega, M.C, Carrascosa, J.L, Coll, M. | Deposit date: | 2019-11-26 | Release date: | 2020-12-16 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.74 Å) | Cite: | Using a partial atomic model from medium-resolution cryo-EM to solve a large crystal structure. Acta Crystallogr D Struct Biol, 77, 2021
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8B4C
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![BU of 8b4c by Molmil](/molmil-images/mine/8b4c) | ToxR bacterial transcriptional regulator bound to 20 bp toxT promoter DNA | Descriptor: | Cholera toxin transcriptional activator, DNA (20-MER) | Authors: | Canals, A, Pieretti, S, Muriel, M, El Yaman, N, Fabrega-Ferrer, M, Perez-Luque, R, Krukonis, E.S, Coll, M. | Deposit date: | 2022-09-20 | Release date: | 2023-08-09 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | ToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites. Proc.Natl.Acad.Sci.USA, 120, 2023
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8B4E
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![BU of 8b4e by Molmil](/molmil-images/mine/8b4e) | ToxR bacterial transcriptional regulator bound to 25 bp toxT promoter DNA | Descriptor: | Cholera toxin transcriptional activator, DNA (25-MER) | Authors: | Canals, A, Pieretti, S, Muriel, M, El Yaman, N, Fabrega-Ferrer, M, Perez-Luque, R, Krukonis, E.S, Coll, M. | Deposit date: | 2022-09-20 | Release date: | 2023-08-09 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | ToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites. Proc.Natl.Acad.Sci.USA, 120, 2023
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8B4B
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![BU of 8b4b by Molmil](/molmil-images/mine/8b4b) | ToxR bacterial transcriptional regulator bound to 19 bp ompU promoter DNA | Descriptor: | AMMONIUM ION, CADMIUM ION, Cholera toxin transcriptional activator, ... | Authors: | Canals, A, Pieretti, S, Muriel, M, El Yaman, N, Fabrega-Ferrer, M, Perez-Luque, R, Krukonis, E.S, Coll, M. | Deposit date: | 2022-09-20 | Release date: | 2023-08-09 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | ToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites. Proc.Natl.Acad.Sci.USA, 120, 2023
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8B4D
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![BU of 8b4d by Molmil](/molmil-images/mine/8b4d) | ToxR bacterial transcriptional regulator bound to 40 bp toxT promoter DNA | Descriptor: | Cholera toxin transcriptional activator, DNA (40-MER) | Authors: | Canals, A, Pieretti, S, Muriel, M, El Yaman, N, Fabrega-Ferrer, M, Perez-Luque, R, Krukonis, E.S, Coll, M. | Deposit date: | 2022-09-20 | Release date: | 2023-08-09 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | ToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites. Proc.Natl.Acad.Sci.USA, 120, 2023
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7ZQW
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![BU of 7zqw by Molmil](/molmil-images/mine/7zqw) | Structure of the SARS-CoV-1 main protease in complex with AG7404 | Descriptor: | 3C-like proteinase nsp5, ethyl (4R)-4-({(2S)-2-[3-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-2-oxopyridin-1(2H)-yl]pent-4-ynoyl}amino)-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate | Authors: | Muriel-Goni, S, Fabrega-Ferrer, M, Herrera-Morande, A, Coll, M. | Deposit date: | 2022-05-03 | Release date: | 2022-12-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404. Antiviral Res., 208, 2022
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7ZQV
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![BU of 7zqv by Molmil](/molmil-images/mine/7zqv) | Structure of the SARS-CoV-2 main protease in complex with AG7404 | Descriptor: | 3C-like proteinase nsp5, ethyl (4R)-4-({(2S)-2-[3-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-2-oxopyridin-1(2H)-yl]pent-4-ynoyl}amino)-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate | Authors: | Fabrega-Ferrer, M, Herrera-Morande, A, Perez-Saavedra, J, Coll, M. | Deposit date: | 2022-05-03 | Release date: | 2022-12-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404. Antiviral Res., 208, 2022
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6RVS
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![BU of 6rvs by Molmil](/molmil-images/mine/6rvs) | Atomic structure of the Epstein-Barr portal, structure II | Descriptor: | Portal protein | Authors: | Machon, C, Fabrega-Ferrer, M, Zhou, D, Cuervo, A, Carrascosa, J.L, Stuart, D.I, Coll, M. | Deposit date: | 2019-05-31 | Release date: | 2019-09-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Atomic structure of the Epstein-Barr virus portal. Nat Commun, 10, 2019
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6RVR
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![BU of 6rvr by Molmil](/molmil-images/mine/6rvr) | Atomic structure of the Epstein-Barr portal, structure I | Descriptor: | Portal protein | Authors: | Machon, C, Fabrega-Ferrer, M, Zhou, D, Cuervo, A, Carrascosa, J.L, Stuart, D.I, Coll, M. | Deposit date: | 2019-05-31 | Release date: | 2019-09-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Atomic structure of the Epstein-Barr virus portal. Nat Commun, 10, 2019
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7QYF
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![BU of 7qyf by Molmil](/molmil-images/mine/7qyf) | Structure of the transaminase PluriZyme variant (TR2E2) | Descriptor: | Aminotransferase TR2 | Authors: | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | Deposit date: | 2022-01-28 | Release date: | 2023-07-26 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions. Angew Chem Int Ed Engl, 61, 2022
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7QX3
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![BU of 7qx3 by Molmil](/molmil-images/mine/7qx3) | Structure of the transaminase TR2E2 with EOS | Descriptor: | 2-azanylethyl hydrogen sulfate, Aminotransferase TR2 | Authors: | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | Deposit date: | 2022-01-26 | Release date: | 2023-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions. Angew.Chem.Int.Ed.Engl., 61, 2022
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7QX0
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![BU of 7qx0 by Molmil](/molmil-images/mine/7qx0) | Transaminase Structure of Plurienzyme (Tr2E2) in complex with PLP | Descriptor: | Aminotransferase TR2, PYRIDOXAL-5'-PHOSPHATE | Authors: | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | Deposit date: | 2022-01-26 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions. Angew Chem Int Ed Engl, 61, 2022
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7QYG
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![BU of 7qyg by Molmil](/molmil-images/mine/7qyg) | Structure of the transaminase TR2 | Descriptor: | Aminotransferase TR2 | Authors: | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | Deposit date: | 2022-01-28 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions. Angew Chem Int Ed Engl, 61, 2022
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1Y2Y
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![BU of 1y2y by Molmil](/molmil-images/mine/1y2y) | Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy | Descriptor: | Ribosome biogenesis protein Nop10 | Authors: | Khanna, M, Wu, H, Johansson, C, Caizergues-Ferrer, M, Feigon, J. | Deposit date: | 2004-11-23 | Release date: | 2005-12-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA RNA, 12, 2006
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4Q3K
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![BU of 4q3k by Molmil](/molmil-images/mine/4q3k) | Crystal structure of MGS-M1, an alpha/beta hydrolase enzyme from a Medee basin deep-sea metagenome library | Descriptor: | CHLORIDE ION, FLUORIDE ION, MGS-M1, ... | Authors: | Stogios, P.J, Xu, X, Cui, H, Alcaide, M, Ferrer, M, Savchenko, A. | Deposit date: | 2014-04-11 | Release date: | 2015-02-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats. Environ Microbiol, 17, 2015
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4Q3L
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![BU of 4q3l by Molmil](/molmil-images/mine/4q3l) | Crystal structure of MGS-M2, an alpha/beta hydrolase enzyme from a Medee basin deep-sea metagenome library | Descriptor: | GLYCEROL, MGS-M2 | Authors: | Stogios, P.J, Xu, X, Cui, H, Alcaide, M, Ferrer, M, Savchenko, A. | Deposit date: | 2014-04-11 | Release date: | 2015-02-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats. Environ Microbiol, 17, 2015
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4Q3N
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![BU of 4q3n by Molmil](/molmil-images/mine/4q3n) | Crystal structure of MGS-M5, a lactate dehydrogenase enzyme from a Medee basin deep-sea metagenome library | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Stogios, P.J, Xu, X, Cui, H, Alcaide, M, Ferrer, M, Savchenko, A. | Deposit date: | 2014-04-11 | Release date: | 2015-02-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats. Environ Microbiol, 17, 2015
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4Q3O
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![BU of 4q3o by Molmil](/molmil-images/mine/4q3o) | Crystal structure of MGS-MT1, an alpha/beta hydrolase enzyme from a Lake Matapan deep-sea metagenome library | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... | Authors: | Stogios, P.J, Xu, X, Cui, H, Alcaide, M, Ferrer, M, Savchenko, A. | Deposit date: | 2014-04-11 | Release date: | 2015-03-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats. Environ Microbiol, 17, 2015
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