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PDB: 121 results

7W96
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BU of 7w96 by Molmil
Solution structures of a disulfide-rich peptide that can bind KEAP1
Descriptor: drp6
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-09
Release date:2022-11-09
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8T
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BU of 7w8t by Molmil
Solution structures of a disulfide-rich peptide that can bind KEAP1
Descriptor: DRP3
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-08
Release date:2022-06-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8R
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BU of 7w8r by Molmil
Solution structures of a disulfide-rich peptide that can bind mdm2
Descriptor: drp2-b
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-08
Release date:2022-06-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8K
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BU of 7w8k by Molmil
Solution structures of a disulfide-rich peptide that can bind mdm2
Descriptor: drp1
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-08
Release date:2022-06-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8O
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BU of 7w8o by Molmil
Solution structures of a disulfide-rich peptide that can bind mdm2
Descriptor: drp2-a
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-08
Release date:2022-06-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8Z
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BU of 7w8z by Molmil
Solution structures of a disulfide-rich peptide designed through sequence grafting
Descriptor: drp4
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-09
Release date:2022-06-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7WEI
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BU of 7wei by Molmil
Solution structures of a disulfide-rich peptide that can bind CD28
Descriptor: drp8I
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-23
Release date:2022-11-09
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7WE3
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BU of 7we3 by Molmil
Solution structures of a disulfide-rich peptide that can bind CD28
Descriptor: DRP8II
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-22
Release date:2022-11-09
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7ELG
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BU of 7elg by Molmil
LC3B modificated with a covalent probe
Descriptor: 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
Authors:Fan, S, Wan, W.
Deposit date:2021-04-10
Release date:2021-10-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
7ELY
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BU of 7ely by Molmil
A peptide with high affinity for B-Cell lymphoma2(Bcl-2)
Descriptor: 16X_BCL
Authors:Fan, S, Zha, J, Wu, C.
Deposit date:2021-04-12
Release date:2021-05-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:An evolution-inspired strategy to design disulfide-rich peptides tolerant to extensive sequence manipulation.
Chem Sci, 12, 2021
7VEG
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BU of 7veg by Molmil
Understanding NH-pi interaction between Gln and Phe
Descriptor: (2~{S},4~{R})-4-oxidanylpyrrolidine-2-carboxamide, ACETYLAMINO-ACETIC ACID, peptide
Authors:Fan, S, Xu, F.
Deposit date:2021-09-08
Release date:2022-10-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.385 Å)
Cite:Structural Achievability of an NH-pi Interaction between Gln and Phe in a Crystal Structure of a Collagen-like Peptide.
Biomolecules, 12, 2022
7DG0
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BU of 7dg0 by Molmil
Structure and function of Diadenylate cyclase DacM in Mycoplasma ovipneumoniae
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DAC domain-containing protein
Authors:Fan, S.L.
Deposit date:2020-11-10
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Structure and function of Diadenylate cyclase DacM in Mycoplasma ovipneumoniae
To Be Published
7DFX
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BU of 7dfx by Molmil
Structure and function of Diadenylate cyclase DacM in Mycoplasma ovipneumoniae
Descriptor: DAC domain-containing protein, MALONIC ACID
Authors:Fan, S, Li, M.
Deposit date:2020-11-10
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.996 Å)
Cite:Structure and function of Diadenylate cyclase DacM in Mycoplasma ovipneumoniae
To Be Published
7YRX
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BU of 7yrx by Molmil
Solution structures of a disulfide-directed multicyclic peptide with affinity for HER3
Descriptor: LH3
Authors:Fan, S.H, Wu, C.L.
Deposit date:2022-08-11
Release date:2023-08-16
Method:SOLUTION NMR
Cite:Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Pep-tide Ligands and Drugs
To Be Published
5F9Q
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BU of 5f9q by Molmil
Crystal structure of the extracellular domain of noncanonic ABC-type transporter YknZ from Gram-positive bacteria
Descriptor: Macrolide export ATP-binding/permease protein YknZ
Authors:Xu, Y, Guo, J, Jiang, R, Jin, X, Fan, S, Quan, C.S, Ha, N.C.
Deposit date:2015-12-10
Release date:2016-02-03
Last modified:2016-09-14
Method:X-RAY DIFFRACTION (2.044 Å)
Cite:The Crystal Structure of the YknZ Extracellular Domain of ABC Transporter YknWXYZ from Bacillus amyloliquefaciens.
Plos One, 11, 2016
4FQG
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BU of 4fqg by Molmil
Crystal structure of the TCERG1 FF4-6 tandem repeat domain
Descriptor: CHLORIDE ION, NICKEL (II) ION, Transcription elongation regulator 1
Authors:Liu, J, Fan, S, Lee, C.J, Greenleaf, A.L, Zhou, P.
Deposit date:2012-06-25
Release date:2013-02-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain Repeat.
J.Biol.Chem., 288, 2013
7TE7
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BU of 7te7 by Molmil
Estrogen Receptor Alpha Ligand Binding Domain in Complex with RAD1901
Descriptor: (6R)-6-{2-[ethyl({4-[2-(ethylamino)ethyl]phenyl}methyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol, Estrogen receptor
Authors:Joiner, C, Hancock, G, Young, K, Hosfield, D.J, Greene, G.L, Fanning, S.W.
Deposit date:2022-01-04
Release date:2022-01-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells.
NPJ Breast Cancer, 8, 2022
8W6P
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BU of 8w6p by Molmil
Crystal structure of dimeric murine SMPDL3A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ...
Authors:Zhang, C, Liu, P, Fan, S, Hou, Y.
Deposit date:2023-08-29
Release date:2023-12-20
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing.
Immunity, 56, 2023
7SFO
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BU of 7sfo by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 3-(((2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methyl)phenol and GRIP Peptide
Descriptor: 3-{[(2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino]methyl}phenol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:Joyner, C, Reddy, V.K, Wilson, T, Fanning, S.W.
Deposit date:2021-10-04
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estrogen Receptor Alpha
To Be Published
5MK5
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BU of 5mk5 by Molmil
Structures of DHBN domain of human BLM helicase
Descriptor: Bloom syndrome protein, IODIDE ION, POTASSIUM ION
Authors:Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G.
Deposit date:2016-12-02
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
8W6R
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BU of 8w6r by Molmil
murine SMPDL3A bound to sulfate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ...
Authors:Zhang, C, Liu, P, Fan, S.
Deposit date:2023-08-29
Release date:2023-12-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing.
Immunity, 56, 2023
5LUS
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BU of 5lus by Molmil
Structures of DHBN domain of Pelecanus crispus BLM helicase
Descriptor: BLM helicase
Authors:Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G.
Deposit date:2016-09-09
Release date:2017-03-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.433 Å)
Cite:A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
5LUP
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BU of 5lup by Molmil
Structures of DHBN domain of human BLM helicase
Descriptor: BLM protein, PHOSPHATE ION, POTASSIUM ION
Authors:Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G.
Deposit date:2016-09-09
Release date:2017-03-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.032 Å)
Cite:A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
5LUT
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BU of 5lut by Molmil
Structures of DHBN domain of Gallus gallus BLM helicase
Descriptor: BLM helicase, PHOSPHATE ION
Authors:Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G.
Deposit date:2016-09-09
Release date:2017-03-01
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
7UJ8
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BU of 7uj8 by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 4-Hydroxytamoxifen
Descriptor: 4-HYDROXYTAMOXIFEN, Estrogen receptor
Authors:Hosfield, D.J, Greene, G.L, Fanning, S.W.
Deposit date:2022-03-30
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.385 Å)
Cite:Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022

221051

数据于2024-06-12公开中

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