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PDB: 121 件

7W96
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Solution structures of a disulfide-rich peptide that can bind KEAP1
分子名称: drp6
著者Fan, S.H, Wu, Y.P, Wu, C.L.
登録日2021-12-09
公開日2022-11-09
実験手法SOLUTION NMR
主引用文献Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8T
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BU of 7w8t by Molmil
Solution structures of a disulfide-rich peptide that can bind KEAP1
分子名称: DRP3
著者Fan, S.H, Wu, Y.P, Wu, C.L.
登録日2021-12-08
公開日2022-06-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8R
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BU of 7w8r by Molmil
Solution structures of a disulfide-rich peptide that can bind mdm2
分子名称: drp2-b
著者Fan, S.H, Wu, Y.P, Wu, C.L.
登録日2021-12-08
公開日2022-06-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8K
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Solution structures of a disulfide-rich peptide that can bind mdm2
分子名称: drp1
著者Fan, S.H, Wu, Y.P, Wu, C.L.
登録日2021-12-08
公開日2022-06-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8O
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BU of 7w8o by Molmil
Solution structures of a disulfide-rich peptide that can bind mdm2
分子名称: drp2-a
著者Fan, S.H, Wu, Y.P, Wu, C.L.
登録日2021-12-08
公開日2022-06-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8Z
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BU of 7w8z by Molmil
Solution structures of a disulfide-rich peptide designed through sequence grafting
分子名称: drp4
著者Fan, S.H, Wu, Y.P, Wu, C.L.
登録日2021-12-09
公開日2022-06-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7WEI
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BU of 7wei by Molmil
Solution structures of a disulfide-rich peptide that can bind CD28
分子名称: drp8I
著者Fan, S.H, Wu, Y.P, Wu, C.L.
登録日2021-12-23
公開日2022-11-09
実験手法SOLUTION NMR
主引用文献Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7WE3
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BU of 7we3 by Molmil
Solution structures of a disulfide-rich peptide that can bind CD28
分子名称: DRP8II
著者Fan, S.H, Wu, Y.P, Wu, C.L.
登録日2021-12-22
公開日2022-11-09
実験手法SOLUTION NMR
主引用文献Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7ELG
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BU of 7elg by Molmil
LC3B modificated with a covalent probe
分子名称: 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
著者Fan, S, Wan, W.
登録日2021-04-10
公開日2021-10-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
7ELY
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A peptide with high affinity for B-Cell lymphoma2(Bcl-2)
分子名称: 16X_BCL
著者Fan, S, Zha, J, Wu, C.
登録日2021-04-12
公開日2021-05-19
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献An evolution-inspired strategy to design disulfide-rich peptides tolerant to extensive sequence manipulation.
Chem Sci, 12, 2021
7VEG
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BU of 7veg by Molmil
Understanding NH-pi interaction between Gln and Phe
分子名称: (2~{S},4~{R})-4-oxidanylpyrrolidine-2-carboxamide, ACETYLAMINO-ACETIC ACID, peptide
著者Fan, S, Xu, F.
登録日2021-09-08
公開日2022-10-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.385 Å)
主引用文献Structural Achievability of an NH-pi Interaction between Gln and Phe in a Crystal Structure of a Collagen-like Peptide.
Biomolecules, 12, 2022
7DG0
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Structure and function of Diadenylate cyclase DacM in Mycoplasma ovipneumoniae
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DAC domain-containing protein
著者Fan, S.L.
登録日2020-11-10
公開日2021-11-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献Structure and function of Diadenylate cyclase DacM in Mycoplasma ovipneumoniae
To Be Published
7DFX
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Structure and function of Diadenylate cyclase DacM in Mycoplasma ovipneumoniae
分子名称: DAC domain-containing protein, MALONIC ACID
著者Fan, S, Li, M.
登録日2020-11-10
公開日2021-11-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.996 Å)
主引用文献Structure and function of Diadenylate cyclase DacM in Mycoplasma ovipneumoniae
To Be Published
7YRX
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BU of 7yrx by Molmil
Solution structures of a disulfide-directed multicyclic peptide with affinity for HER3
分子名称: LH3
著者Fan, S.H, Wu, C.L.
登録日2022-08-11
公開日2023-08-16
実験手法SOLUTION NMR
主引用文献Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Pep-tide Ligands and Drugs
To Be Published
5F9Q
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BU of 5f9q by Molmil
Crystal structure of the extracellular domain of noncanonic ABC-type transporter YknZ from Gram-positive bacteria
分子名称: Macrolide export ATP-binding/permease protein YknZ
著者Xu, Y, Guo, J, Jiang, R, Jin, X, Fan, S, Quan, C.S, Ha, N.C.
登録日2015-12-10
公開日2016-02-03
最終更新日2016-09-14
実験手法X-RAY DIFFRACTION (2.044 Å)
主引用文献The Crystal Structure of the YknZ Extracellular Domain of ABC Transporter YknWXYZ from Bacillus amyloliquefaciens.
Plos One, 11, 2016
4FQG
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BU of 4fqg by Molmil
Crystal structure of the TCERG1 FF4-6 tandem repeat domain
分子名称: CHLORIDE ION, NICKEL (II) ION, Transcription elongation regulator 1
著者Liu, J, Fan, S, Lee, C.J, Greenleaf, A.L, Zhou, P.
登録日2012-06-25
公開日2013-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain Repeat.
J.Biol.Chem., 288, 2013
7TE7
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BU of 7te7 by Molmil
Estrogen Receptor Alpha Ligand Binding Domain in Complex with RAD1901
分子名称: (6R)-6-{2-[ethyl({4-[2-(ethylamino)ethyl]phenyl}methyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol, Estrogen receptor
著者Joiner, C, Hancock, G, Young, K, Hosfield, D.J, Greene, G.L, Fanning, S.W.
登録日2022-01-04
公開日2022-01-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells.
NPJ Breast Cancer, 8, 2022
8W6P
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BU of 8w6p by Molmil
Crystal structure of dimeric murine SMPDL3A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ...
著者Zhang, C, Liu, P, Fan, S, Hou, Y.
登録日2023-08-29
公開日2023-12-20
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing.
Immunity, 56, 2023
7SFO
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BU of 7sfo by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 3-(((2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methyl)phenol and GRIP Peptide
分子名称: 3-{[(2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino]methyl}phenol, Estrogen receptor, Nuclear receptor coactivator 2
著者Joyner, C, Reddy, V.K, Wilson, T, Fanning, S.W.
登録日2021-10-04
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Estrogen Receptor Alpha
To Be Published
5MK5
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BU of 5mk5 by Molmil
Structures of DHBN domain of human BLM helicase
分子名称: Bloom syndrome protein, IODIDE ION, POTASSIUM ION
著者Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G.
登録日2016-12-02
公開日2017-03-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
8W6R
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BU of 8w6r by Molmil
murine SMPDL3A bound to sulfate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ...
著者Zhang, C, Liu, P, Fan, S.
登録日2023-08-29
公開日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing.
Immunity, 56, 2023
5LUS
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BU of 5lus by Molmil
Structures of DHBN domain of Pelecanus crispus BLM helicase
分子名称: BLM helicase
著者Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G.
登録日2016-09-09
公開日2017-03-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.433 Å)
主引用文献A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
5LUP
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BU of 5lup by Molmil
Structures of DHBN domain of human BLM helicase
分子名称: BLM protein, PHOSPHATE ION, POTASSIUM ION
著者Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G.
登録日2016-09-09
公開日2017-03-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.032 Å)
主引用文献A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
5LUT
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BU of 5lut by Molmil
Structures of DHBN domain of Gallus gallus BLM helicase
分子名称: BLM helicase, PHOSPHATE ION
著者Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G.
登録日2016-09-09
公開日2017-03-01
最終更新日2017-04-19
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
7UJ8
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BU of 7uj8 by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 4-Hydroxytamoxifen
分子名称: 4-HYDROXYTAMOXIFEN, Estrogen receptor
著者Hosfield, D.J, Greene, G.L, Fanning, S.W.
登録日2022-03-30
公開日2022-06-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.385 Å)
主引用文献Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022

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件を2024-06-12に公開中

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