2BLH
 
 | | Ligand Migration and Protein Fluctuations in Myoglobin Mutant L29W | | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Nienhaus, K, Ostermann, A, Nienhaus, G.U, Parak, F.G, Schmidt, M. | | 登録日 | 2005-03-04 | | 公開日 | 2005-04-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Ligand Migration and Protein Fluctuations in Myoglobin Mutant L29W
Biochemistry, 44, 2005
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2D3R
 | | Cratylia folibunda seed lectin at acidic pH | | 分子名称: | CALCIUM ION, Lectin alpha chain, MANGANESE (II) ION | | 著者 | Del Sol, F.G, Cavada, B.S, Calvete, J.J. | | 登録日 | 2005-09-30 | | 公開日 | 2005-11-10 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of Cratylia floribunda seed lectin at acidic and basic pHs. Insights into the structural basis of the pH-dependent dimer-tetramer transition.
J.Struct.Biol., 158, 2007
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2D3P
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2A6L
 | | Dihydrodipicolinate synthase (E. coli)- mutant R138H | | 分子名称: | Dihydrodipicolinate synthase, POTASSIUM ION | | 著者 | Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2005-07-03 | | 公開日 | 2005-10-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase.
Biochemistry, 44, 2005
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2AAB
 | | Structural basis of antigen mimicry in a clinically relevant melanoma antigen system | | 分子名称: | anti-idiotypic monoclonal antibody (heavy chain), anti-idiotypic monoclonal antibody (light chain) | | 著者 | Chang, C.-C, Hernandez-Guzman, F.G, Luo, W, Wang, X, Ferrone, S, Ghosh, D. | | 登録日 | 2005-07-13 | | 公開日 | 2005-10-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis of antigen mimicry in a clinically relevant melanoma antigen system.
J.Biol.Chem., 280, 2005
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2A4G
 | | Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound | | 分子名称: | ({1-[1-CARBAMOYL-PHENYL-METHYL)-CARBAMOYL]-METHYL}-AMINOOXALYL)-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL)-CYCLOHEXYL-METHYL)-CARBAMIC ACID ISOBUTYL ESTER, NS3 protease/helicase, NS4a peptide, ... | | 著者 | Arasappan, A, Njoroge, F.G, Chan, T.Y, Bennett, F, Bogen, S.L, Chen, K, Gu, H, Hong, L, Jao, E, Liu, Y.T, Lovey, R.G, Parekh, T, Pike, R.E, Pinto, P, Santhanam, B, Venkatraman, S, Vaccaro, H, Wang, H, Yang, X, Zhu, Z, Mckittrick, B, Saksena, A.K, Girijavallabhan, V, Pichardo, J, Butkiewicz, N, Ingram, R, Malcolm, B, Prongay, A.J, Yao, N, Marten, B, Madison, V, Kemp, S, Levy, O, Lim-Wilby, M, Tamura, S, Ganguly, A.K. | | 登録日 | 2005-06-28 | | 公開日 | 2006-07-04 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Hepatitis C virus NS3-4a serine protease inhibitors. SAR of P2' moiety with improved potency.
Bioorg.Med.Chem.Lett., 15, 2005
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2A6N
 | | Dihydrodipicolinate synthase (E. coli)- mutant R138A | | 分子名称: | Dihydrodipicolinate synthase, POTASSIUM ION | | 著者 | Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2005-07-03 | | 公開日 | 2005-10-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase.
Biochemistry, 44, 2005
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4BK8
 | | Superoxide reductase (Neelaredoxin) from Ignicoccus hospitalis | | 分子名称: | DESULFOFERRODOXIN, FERROUS IRON-BINDING REGION, FE (III) ION | | 著者 | Romao, C.V, Matias, P.M, Pinho, F.G, Sousa, C.M, Barradas, A.R, Pinto, A.F, Teixeira, M, Bandeiras, T.M. | | 登録日 | 2013-04-22 | | 公開日 | 2014-04-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.847 Å) | | 主引用文献 | Structure of a Natural Sor Mutant
To be Published
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3GW3
 | | human UROD mutant K297N | | 分子名称: | Uroporphyrinogen decarboxylase | | 著者 | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | | 登録日 | 2009-03-31 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and kinetic characterization of mutant human uroporphyrinogen decarboxylases.
Cell Mol Biol (Noisy-le-grand), 55, 2009
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3GVQ
 | | UROD single-chain dimer | | 分子名称: | Uroporphyrinogen decarboxylase | | 著者 | Hill, C.P, Phillips, J.D, Warby, C, Whitby, F.G, Kushner, J.P. | | 登録日 | 2009-03-31 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen.
J.Mol.Biol., 389, 2009
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3GW0
 | | UROD mutant G318R | | 分子名称: | Uroporphyrinogen decarboxylase | | 著者 | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | | 登録日 | 2009-03-31 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and kinetic characterization of mutant human uroporphyrinogen decarboxylases.
Cell Mol Biol (Noisy-le-grand), 55, 2009
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3GVW
 | | Single-chain UROD F217Y (YF) mutation | | 分子名称: | Uroporphyrinogen decarboxylase | | 著者 | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | | 登録日 | 2009-03-31 | | 公開日 | 2009-12-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen.
J.Mol.Biol., 389, 2009
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3JRM
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3GVR
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3JSE
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3GVV
 | | Single-chain UROD Y164G (GY) mutation | | 分子名称: | Uroporphyrinogen decarboxylase | | 著者 | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | | 登録日 | 2009-03-31 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen.
J.Mol.Biol., 389, 2009
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5UD6
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5UI3
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5UXT
 | | Coiled-coil Trimer with Glu:Trp:Lys Triad | | 分子名称: | GLYCEROL, coiled-coil trimer with Glu:Trp:Lys triad | | 著者 | Smith, M.S, Billings, W.M, Whitby, F.G, Miller, M.B, Price, J.L. | | 登録日 | 2017-02-23 | | 公開日 | 2017-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | | 主引用文献 | Enhancing a long-range salt bridge with intermediate aromatic and nonpolar amino acids.
Org. Biomol. Chem., 15, 2017
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5VKO
 | | SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493 | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, ISOPROPYL ALCOHOL, Transcription elongation factor SPT6 | | 著者 | Sdano, M.A, Whitby, F.G, Hill, C.P. | | 登録日 | 2017-04-21 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.
Elife, 6, 2017
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5VKL
 | | SPT6 tSH2-RPB1 1476-1500 pS1493 | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, Transcription elongation factor SPT6 | | 著者 | Sdano, M.A, Whitby, F.G, Hill, C.P. | | 登録日 | 2017-04-21 | | 公開日 | 2017-10-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.
Elife, 6, 2017
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3DEN
 | | Structure of E. coli DHDPS mutant Y107W | | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Pearce, F.G, Gerrard, J.A, Perugini, M.A, Jameson, G.B. | | 登録日 | 2008-06-10 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme
Biochemistry, 47, 2008
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3EAW
 | | Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase | | 著者 | Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H. | | 登録日 | 2008-08-26 | | 公開日 | 2010-03-02 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
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3B98
 | | Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1) | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Prostaglandin I2 synthase | | 著者 | Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. | | 登録日 | 2007-11-03 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change
J.Biol.Chem., 283, 2008
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3EF9
 | | Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability | | 分子名称: | SULFATE ION, Thymidylate synthase | | 著者 | Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H. | | 登録日 | 2008-09-08 | | 公開日 | 2010-03-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
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