3DEN

Structure of E. coli DHDPS mutant Y107W

Summary for 3DEN

Entry DOI	10.2210/pdb3den/pdb
Descriptor	Dihydrodipicolinate synthase, POTASSIUM ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	dihydrodipicolinate synthase, monomer, quaternary structure, amino-acid biosynthesis, diaminopimelate biosynthesis, lyase, lysine biosynthesis, schiff base
Biological source	Escherichia coli K-12
Cellular location	Cytoplasm: P0A6L2
Total number of polymer chains	2
Total formula weight	63549.47
Authors	Pearce, F.G.,Gerrard, J.A.,Perugini, M.A.,Jameson, G.B. (deposition date: 2008-06-10, release date: 2008-11-25, Last modification date: 2023-11-01)
Primary citation	Pearce, F.G.,Dobson, R.C.J.,Weber, A.,Lane, L.A.,McCammon, M.G.,Squire, M.A.,Perugini, M.A.,Jameson, G.B.,Robinson, C.V.,Gerrard, J.A. Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme Biochemistry, 47:12108-12117, 2008 Cited by PubMed: 18937497 DOI: 10.1021/bi801094t PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation