7TBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tbv by Molmil](/molmil-images/mine/7tbv) | Crystal structure of the shikimate kinase + 3-dehydroquinate dehydratase + 3-dehydroshikimate dehydrogenase domains of Aro1 from Candida albicans | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Stogios, P.J, Evdokimova, E, Michalska, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-12-22 | Release date: | 2022-03-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance, 5, 2022
|
|
6OSX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6osx by Molmil](/molmil-images/mine/6osx) | Crystal structure of uncharacterized protein ECL_02694 | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, Protein YmbA, ... | Authors: | Chang, C, Evdokimova, E, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-05-02 | Release date: | 2019-05-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of uncharacterized protein ECL_02694 To Be Published
|
|
1KXJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kxj by Molmil](/molmil-images/mine/1kxj) | The Crystal Structure of Glutamine Amidotransferase from Thermotoga maritima | Descriptor: | Amidotransferase hisH, PHOSPHATE ION | Authors: | Korolev, S, Skarina, T, Evdokimova, E, Beasley, S, Edwards, A, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2002-01-31 | Release date: | 2002-03-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of glutamine amidotransferase from Thermotoga maritima Proteins, 49, 2002
|
|
3N99
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3n99 by Molmil](/molmil-images/mine/3n99) | Crystal structure of TM1086 | Descriptor: | CHLORIDE ION, uncharacterized protein TM1086 | Authors: | Chruszcz, M, Domagalski, M.J, Wang, S, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-05-28 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Crystal structure of TM1086 To be Published
|
|
4MUT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mut by Molmil](/molmil-images/mine/4mut) | Crystal structure of vancomycin resistance D,D-dipeptidase/D,D-pentapeptidase VanXYc D59S mutant in complex with D-Alanine | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, D,D-dipeptidase/D,D-carboxypeptidase, ... | Authors: | Stogios, P.J, Evdokimova, E, Meziane-Cherif, D, Di Leo, R, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-09-23 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis for the evolution of vancomycin resistance D,D-peptidases. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
2FBI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fbi by Molmil](/molmil-images/mine/2fbi) | The crystal structure of transcriptional regulator PA4135 | Descriptor: | probable transcriptional regulator | Authors: | Lunin, V.V, Evdokimova, E, Kudritska, M, Cuff, M.E, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-09 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of transcriptional regulator PA4135 To be Published
|
|
7LAO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lao by Molmil](/molmil-images/mine/7lao) | Crystal structure of aminoglycoside acetyltransferase AAC(3)-IIb | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Aminoglycoside N(3)-acetyltransferase III, MAGNESIUM ION | Authors: | Stogios, P.J, Evdokimova, E, Osipiuk, J, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-01-06 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5, 2022
|
|
1KTN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ktn by Molmil](/molmil-images/mine/1ktn) | Structural Genomics, Protein EC1535 | Descriptor: | 2-deoxyribose-5-phosphate aldolase | Authors: | Zhang, R, Joachimiak, A, Edwards, A, Skarina, T, Evdokimova, E, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2002-01-16 | Release date: | 2002-08-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The 1.5A crystal structure of
2-deoxyribose-5-phosphate aldlase To be Published
|
|
7UUN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uun by Molmil](/molmil-images/mine/7uun) | Crystal structure of aminoglycoside resistance enzyme ApmA, complex with neomycin | Descriptor: | 1,2-ETHANEDIOL, Aminocyclitol acetyltransferase ApmA, NEOMYCIN | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Osipiuk, J, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | Deposit date: | 2022-04-28 | Release date: | 2022-11-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance. Nat.Chem.Biol., 20, 2024
|
|
4MUS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mus by Molmil](/molmil-images/mine/4mus) | Crystal structure of vancomycin resistance D,D-dipeptidase/D,D-pentapeptidase VanXYc D59S mutant in complex with D-Ala-D-Ala phosphinate analog | Descriptor: | (2R)-3-[(R)-[(1R)-1-aminoethyl](hydroxy)phosphoryl]-2-methylpropanoic acid, (2R)-3-[(R)-[(1S)-1-aminoethyl](hydroxy)phosphoryl]-2-methylpropanoic acid, CHLORIDE ION, ... | Authors: | Stogios, P.J, Evdokimova, E, Meziane-Cherif, D, Di Leo, R, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-09-23 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.675 Å) | Cite: | Structural basis for the evolution of vancomycin resistance D,D-peptidases. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
5US1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5us1 by Molmil](/molmil-images/mine/5us1) | Crystal structure of aminoglycoside acetyltransferase AAC(2')-Ia in complex with N2'-acetylgentamicin C1A and coenzyme A | Descriptor: | (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-(acetylamino)-6-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside, ACETYL COENZYME *A, Aminoglycoside 2'-N-acetyltransferase, ... | Authors: | Stogios, P.J, Evdokimova, E, Xu, Z, Wawrzak, Z, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-02-13 | Release date: | 2017-03-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes. ACS Infect Dis, 4, 2018
|
|
4MUQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4muq by Molmil](/molmil-images/mine/4muq) | Crystal Structure of Vancomycin Resistance D,D-dipeptidase VanXYg in complex with D-Ala-D-Ala phosphinate analog | Descriptor: | (2R)-3-[(R)-[(1R)-1-aminoethyl](hydroxy)phosphoryl]-2-methylpropanoic acid, (2R)-3-[(R)-[(1S)-1-aminoethyl](hydroxy)phosphoryl]-2-methylpropanoic acid, 1,2-ETHANEDIOL, ... | Authors: | Stogios, P.J, Evdokimova, E, Meziane-Cherif, D, Di Leo, R, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-09-23 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.364 Å) | Cite: | Structural basis for the evolution of vancomycin resistance D,D-peptidases. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4MUR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mur by Molmil](/molmil-images/mine/4mur) | Crystal structure of vancomycin resistance D,D-dipeptidase/D,D-pentapeptidase VanXYc D59S mutant | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, D,D-dipeptidase/D,D-carboxypeptidase, ... | Authors: | Stogios, P.J, Evdokimova, E, Meziane-Cherif, D, Di Leo, R, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-09-23 | Release date: | 2013-10-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for the evolution of vancomycin resistance D,D-peptidases. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4OAK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oak by Molmil](/molmil-images/mine/4oak) | Crystal structure of vancomycin resistance D,D-dipeptidase/D,D-pentapeptidase VanXYc D59S mutant in complex with D-Alanine-D-Alanine and copper (II) | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, COPPER (II) ION, ... | Authors: | Stogios, P.J, Evdokimova, E, Meziane-Cherif, D, Di Leo, R, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2014-01-04 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the evolution of vancomycin resistance D,D-peptidases. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
3PF6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pf6 by Molmil](/molmil-images/mine/3pf6) | The structure of uncharacterized protein PP-LUZ7_gp033 from Pseudomonas phage LUZ7. | Descriptor: | CHLORIDE ION, hypothetical protein PP-LUZ7_gp033 | Authors: | Cuff, M.E, Evdokimova, E, Liu, F, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-10-28 | Release date: | 2010-11-10 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The structure of uncharacterized protein PP-LUZ7_gp033 from Pseudomonas phage LUZ7. TO BE PUBLISHED
|
|
2FKB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fkb by Molmil](/molmil-images/mine/2fkb) | Crystal structure of a putative enzyme (possible Nudix hydrolase) from Escherichia Coli K12 | Descriptor: | ACETATE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Nocek, B, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-01-04 | Release date: | 2006-02-21 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a putative enzyme (possible Nudix hydrolase) from Escherichia Coli K12 To be Published
|
|
2IJL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ijl by Molmil](/molmil-images/mine/2ijl) | The structure of a putative ModE from Agrobacterium tumefaciens. | Descriptor: | 1,2-ETHANEDIOL, Molybdenum-binding transcriptional repressor, SULFATE ION | Authors: | Cuff, M.E, Evdokimova, E, Kudritska, M, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-09-29 | Release date: | 2006-10-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of a putative ModE from Agrobacterium tumefaciens. To be Published
|
|
2HXR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hxr by Molmil](/molmil-images/mine/2hxr) | Structure of the ligand binding domain of E. coli CynR, a transcriptional regulator controlling cyanate metabolism | Descriptor: | HTH-type transcriptional regulator cynR | Authors: | Singer, A.U, Cuff, M.E, Evdokimova, E, Kagan, O, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-08-03 | Release date: | 2006-08-22 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The structure of CynR, a transcriptional regulator, both in the presence and absence of sodium azide, its activator ligand To be Published
|
|
2HJS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hjs by Molmil](/molmil-images/mine/2hjs) | The structure of a probable aspartate-semialdehyde dehydrogenase from Pseudomonas aeruginosa | Descriptor: | 1,4-DIETHYLENE DIOXIDE, USG-1 protein homolog | Authors: | Cuff, M.E, Evdokimova, E, Kudritska, M, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-06-30 | Release date: | 2006-08-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of a probable aspartate-semialdehyde dehydrogenase from Pseudomonas aeruginosa To be published
|
|
2FIY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fiy by Molmil](/molmil-images/mine/2fiy) | The crystal structure of the FdhE protein from Pseudomonas aeruginosa | Descriptor: | FE (III) ION, Protein fdhE homolog | Authors: | Zhang, R, Evdokimova, E, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-30 | Release date: | 2006-02-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of the FdhE protein from Pseudomonas aeruginosa PAO1 To be Published
|
|
1SU1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1su1 by Molmil](/molmil-images/mine/1su1) | Structural and biochemical characterization of Yfce, a phosphoesterase from E. coli | Descriptor: | Hypothetical protein yfcE, SULFATE ION, ZINC ION | Authors: | Miller, D.J, Shuvalova, L, Evdokimova, E, Savchenko, A, Yakunin, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-03-25 | Release date: | 2004-08-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural and biochemical characterization of a novel Mn2+-dependent phosphodiesterase encoded by the yfcE gene. Protein Sci., 16, 2007
|
|
2FBH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fbh by Molmil](/molmil-images/mine/2fbh) | The crystal structure of transcriptional regulator PA3341 | Descriptor: | MERCURY (II) ION, SULFATE ION, ZINC ION, ... | Authors: | Lunin, V.V, Evdokimova, E, Kudritska, M, Osipiuk, J, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-09 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of transcriptional regulator PA3341 To be Published
|
|
2FEF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fef by Molmil](/molmil-images/mine/2fef) | The Crystal Structure of Protein PA2201 from Pseudomonas aeruginosa | Descriptor: | 1,2-ETHANEDIOL, hypothetical protein PA2201 | Authors: | Cymborowski, M.T, Chruszcz, M, Wang, S, Shumilin, I, Kudritska, M, Evdokimova, E, Savchenko, A, Edwards, A.M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-15 | Release date: | 2006-01-31 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Crystal Structure of Protein PA2201 from Pseudomonas aeruginosa To be Published
|
|
2G39
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2g39 by Molmil](/molmil-images/mine/2g39) | Crystal structure of coenzyme A transferase from Pseudomonas aeruginosa | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, Acetyl-CoA hydrolase | Authors: | Chang, C, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-02-17 | Release date: | 2006-04-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of coenzyme A transferase from Pseudomonas aeruginosa To be Published
|
|
3NUQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nuq by Molmil](/molmil-images/mine/3nuq) | Structure of a putative nucleotide phosphatase from Saccharomyces cerevisiae | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Dong, A, Yang, C, Singer, A.U, Evdokimova, E, Kudritsdka, M, Brown, G, Edwards, A.M, Joachimiak, A, Savchenko, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-07-07 | Release date: | 2010-08-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of a putative nucleotide phosphatase from Saccharomyces cerevisiae To be Published
|
|