4MUQ
Crystal Structure of Vancomycin Resistance D,D-dipeptidase VanXYg in complex with D-Ala-D-Ala phosphinate analog
Summary for 4MUQ
Entry DOI | 10.2210/pdb4muq/pdb |
Related | 4F78 4MUR 4MUS 4MUT 4OAK |
Descriptor | D,D-dipeptidase/D,D-carboxypeptidase, ZINC ION, (2R)-3-[(R)-[(1R)-1-aminoethyl](hydroxy)phosphoryl]-2-methylpropanoic acid, ... (8 entities in total) |
Functional Keywords | center for structural genomics of infectious diseases, csgid, national institute of allergy and infectious diseases, niaid, alpha+beta protein, metallopeptidase, hedgehog/dd-peptidase fold, merops m15b subfamily, zn2+-dependent d, d-dipeptidase, vancomycin resistance, antibiotic resistance, hydrolase |
Biological source | Enterococcus faecalis |
Total number of polymer chains | 1 |
Total formula weight | 32829.34 |
Authors | Stogios, P.J.,Evdokimova, E.,Meziane-Cherif, D.,Di Leo, R.,Yim, V.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2013-09-23, release date: 2013-10-09, Last modification date: 2023-09-20) |
Primary citation | Meziane-Cherif, D.,Stogios, P.J.,Evdokimova, E.,Savchenko, A.,Courvalin, P. Structural basis for the evolution of vancomycin resistance D,D-peptidases. Proc.Natl.Acad.Sci.USA, 111:5872-5877, 2014 Cited by PubMed: 24711382DOI: 10.1073/pnas.1402259111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.364 Å) |
Structure validation
Download full validation report