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PDB: 94 results
8G9N
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BU of 8g9n by Molmil
Partial DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8G99
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BU of 8g99 by Molmil
Partial auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
7LXJ
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BU of 7lxj by Molmil
Bacillus cereus DNA glycosylase AlkD bound to a duocarmycin SA-adenine nucleobase adduct and DNA containing an abasic site
Descriptor: CALCIUM ION, DNA (5'-D(*AP*GP*CP*AP*AP*(ORP)P*GP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*CP*TP*TP*TP*GP*C)-3'), ...
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2021-03-03
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural evolution of a DNA repair self-resistance mechanism targeting genotoxic secondary metabolites.
Nat Commun, 12, 2021
7LXH
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BU of 7lxh by Molmil
Bacillus cereus DNA glycosylase AlkD bound to a CC1065-adenine nucleobase adduct and DNA containing an abasic site
Descriptor: 7-{7-[(1R)-1-{[(4P)-6-amino-3H-purin-3-yl]methyl}-5-hydroxy-8-methyl-1,6-dihydropyrrolo[3,2-e]indole-3(2H)-carbonyl]-4-hydroxy-5-methoxy-1,6-dihydropyrrolo[3,2-e]indole-3(2H)-carbonyl}-4-hydroxy-5-methoxy-1,6-dihydropyrrolo[3,2-e]indole-3(2H)-carboxamide, CALCIUM ION, DNA (5'-D(*AP*GP*CP*AP*AP*(ORP)P*GP*GP*C)-3'), ...
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2021-03-03
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.667 Å)
Cite:Structural evolution of a DNA repair self-resistance mechanism targeting genotoxic secondary metabolites.
Nat Commun, 12, 2021
3EBE
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BU of 3ebe by Molmil
Crystal structure of xenopus laevis replication initiation factor MCM10 internal domain
Descriptor: Protein MCM10 homolog, ZINC ION
Authors:Warren, E.M, Eichman, B.F.
Deposit date:2008-08-27
Release date:2008-12-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for DNA binding by replication initiator mcm10.
Structure, 16, 2008
8UCU
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BU of 8ucu by Molmil
Partial DNA termination subcomplex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-09-27
Release date:2023-10-11
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8UCW
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BU of 8ucw by Molmil
Complete DNA termination subcomplex 2 of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
Authors:Mullins, E.A, Chazin, W.C, Eichman, B.F.
Deposit date:2023-09-27
Release date:2023-10-11
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8UCV
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BU of 8ucv by Molmil
Complete DNA termination subcomplex 1 of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
Authors:Mullins, E.A, Chazin, W.C, Eichman, B.F.
Deposit date:2023-09-27
Release date:2023-10-11
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6J
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BU of 8v6j by Molmil
DNA elongation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-12-01
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (11.11 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V5O
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BU of 8v5o by Molmil
Tetramer core subcomplex (conformation 3) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-11-30
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (8.99 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V5N
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BU of 8v5n by Molmil
Tetramer core subcomplex (conformation 2) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-11-30
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (8.56 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6I
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BU of 8v6i by Molmil
DNA elongation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-12-01
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (14.06 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6G
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BU of 8v6g by Molmil
DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-12-01
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (11.16 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V5M
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BU of 8v5m by Molmil
Tetramer core subcomplex (conformation 1) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-11-30
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (9.22 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6H
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BU of 8v6h by Molmil
DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-12-01
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (11.11 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
4LIK
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BU of 4lik by Molmil
Crystal structure of the catalytic subunit of human primase
Descriptor: CITRIC ACID, DNA primase small subunit, ZINC ION
Authors:Vaithiyalingam, S, Eichman, B.F, Chazin, W.J.
Deposit date:2013-07-02
Release date:2013-12-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase.
J.Mol.Biol., 426, 2014
4JBZ
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BU of 4jbz by Molmil
Structure of Mcm10 coiled-coil region
Descriptor: MALTOSE-BINDING PERIPLASMIC PROTEIN FUSED WITH XENOPUS LAEVIS MCM10 COILED-COIL REGION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Du, W, Adhikary, S, Eichman, B.F.
Deposit date:2013-02-20
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mcm10 self-association is mediated by an N-terminal coiled-coil domain.
Plos One, 8, 2013
4LIL
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BU of 4lil by Molmil
Crystal structure of the catalytic subunit of human primase bound to UTP and Mn
Descriptor: DNA primase small subunit, MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE, ...
Authors:Vaithiyalingam, S, Eichman, B.F, Chazin, W.J.
Deposit date:2013-07-02
Release date:2013-12-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase.
J.Mol.Biol., 426, 2014
3H15
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BU of 3h15 by Molmil
Crystal structure of replication initiation factor MCM10-ID bound to ssDNA
Descriptor: 5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*C)-3', Protein MCM10 homolog, ZINC ION
Authors:Warren, E.M, Eichman, B.F.
Deposit date:2009-04-10
Release date:2009-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Physical Interactions between Mcm10, DNA, and DNA Polymerase {alpha}.
J.Biol.Chem., 284, 2009
3JXY
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BU of 3jxy by Molmil
Bacillus cereus Alkylpurine DNA Glycosylase AlkD Bound to DNA Containing a GT Mismatch
Descriptor: DNA (5'-D(*CP*CP*CP*GP*TP*TP*AP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*AP*CP*TP*GP*AP*CP*GP*GP*G)-3'), alkylpurine DNA glycosylase AlkD
Authors:Rubinson, E.H, Eichman, B.F.
Deposit date:2009-09-21
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:An unprecedented nucleic acid capture mechanism for excision of DNA damage.
Nature, 468, 2010
3JXZ
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BU of 3jxz by Molmil
Bacillus cereus Alkylpurine DNA Glycosylase AlkD Bound to DNA Containing an Abasic Site (across from T)
Descriptor: DNA (5'-D(*AP*AP*AP*GP*CP*CP*TP*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*(3DR)P*GP*GP*CP*TP*T)-3'), alkylpurine DNA glycosylase AlkD
Authors:Rubinson, E.H, Eichman, B.F.
Deposit date:2009-09-21
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:An unprecedented nucleic acid capture mechanism for excision of DNA damage.
Nature, 468, 2010
3JY1
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BU of 3jy1 by Molmil
Bacillus cereus Alkylpurine DNA Glycosylase AlkD Bound to DNA Containing an Abasic Site (across from C)
Descriptor: DNA (5'-D(*AP*AP*AP*GP*CP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*(3DR)P*GP*GP*CP*TP*T)-3'), alkylpurine DNA glycosylase AlkD
Authors:Rubinson, E.H, Eichman, B.F.
Deposit date:2009-09-21
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:An unprecedented nucleic acid capture mechanism for excision of DNA damage.
Nature, 468, 2010
3JX7
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BU of 3jx7 by Molmil
Bacillus cereus alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-METHYLADENINE analog
Descriptor: DNA (5'-D(*CP*CP*CP*GP*TP*TP*AP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*AP*CP*TP*(DZM)P*AP*CP*GP*GP*G)-3'), alkylpurine DNA glycosylase AlkD
Authors:Rubinson, E.H, Eichman, B.F.
Deposit date:2009-09-18
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An unprecedented nucleic acid capture mechanism for excision of DNA damage.
Nature, 468, 2010
4OU0
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BU of 4ou0 by Molmil
Crystal Structure of RPA32C
Descriptor: Replication protein A 32 kDa subunit
Authors:Feldkamp, M.D, Mason, A.C, Eichman, B.F, Chazin, W.J.
Deposit date:2014-02-14
Release date:2014-04-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Analysis of Replication Protein A Recruitment of the DNA Damage Response Protein SMARCAL1.
Biochemistry, 53, 2014
4O66
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BU of 4o66 by Molmil
Crystal Structure of SMARCAL1 HARP substrate recognition domain
Descriptor: SODIUM ION, SULFATE ION, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
Authors:Mason, A.C, Eichman, B.F.
Deposit date:2013-12-20
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structure-specific nucleic acid-binding domain conserved among DNA repair proteins.
Proc.Natl.Acad.Sci.USA, 111, 2014

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