3J07
 
 | | Model of a 24mer alphaB-crystallin multimer | | 分子名称: | Alpha-crystallin B chain | | 著者 | Jehle, S, Vollmar, B, Bardiaux, B, Dove, K.K, Rajagopal, P, Gonen, T, Oschkinat, H, Klevit, R.E. | | 登録日 | 2011-04-27 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (20 Å), SOLID-STATE NMR, SOLUTION SCATTERING | | 主引用文献 | N-terminal domain of {alpha}B-crystallin provides a conformational switch for multimerization and structural heterogeneity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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4NHO
 | | Structure of the spliceosomal DEAD-box protein Prp28 | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, MERCURY (II) ION, ... | | 著者 | Moehlmann, S, Neumann, P, Ficner, R. | | 登録日 | 2013-11-05 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28.
Acta Crystallogr.,Sect.D, 70, 2014
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4NEM
 | | Small molecular fragment bound to crystal contact interface of Interleukin-2 | | 分子名称: | 5-[(2,3-dichlorophenoxy)methyl]furan-2-carboxylic acid, Interleukin-2 | | 著者 | Jehle, S, Brenke, R, Vajda, S, Allen, K.N, Kozakov, D. | | 登録日 | 2013-10-29 | | 公開日 | 2014-11-19 | | 実験手法 | X-RAY DIFFRACTION (1.934 Å) | | 主引用文献 | Small molecular fragments bound to binding energy hot-spot in crystal contact interface of Interleukin-2
To be Published
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2KLR
 | | Solid-state NMR structure of the alpha-crystallin domain in alphaB-crystallin oligomers | | 分子名称: | Alpha-crystallin B chain | | 著者 | Jehle, S, Rajagopal, P, Markovic, S, Bardiaux, B, Kuehne, R, Higman, V.A, Klevit, R.E, van Rossum, B, Oschkinat, H. | | 登録日 | 2009-07-08 | | 公開日 | 2010-07-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Solid-state NMR and SAXS studies provide a structural basis for the activation of alphaB-crystallin oligomers.
Nat.Struct.Mol.Biol., 17, 2010
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4CCA
 | | Structure of human Munc18-2 | | 分子名称: | CHLORIDE ION, SYNTAXIN-BINDING PROTEIN 2 | | 著者 | Hackmann, Y, Graham, S.C, Ehl, S, Hoening, S, Lehmberg, K, Arico, M, Owen, D.J, Griffiths, G.G. | | 登録日 | 2013-10-21 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Syntaxin Binding Mechanism and Disease-Causing Mutations in Munc18-2
Proc.Natl.Acad.Sci.USA, 110, 2013
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8CAV
 | | Discovery of the lanthipeptide Curvocidin and structural insights into its trifunctional synthetase CuvL | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CuvA, MAGNESIUM ION, ... | | 著者 | Sigurdsson, A, Martins, B.M, Duettmann, S.A, Jasyk, M, Dimos-Roehl, B, Schoepf, F, Gemannter, M, Knittel, C.H, Schnegotyzki, R, Schmid, B, Kosol, S, Gonzalez-Viegas, M, Seidel, M, Huegelland, M, Leimkuehler, S, Dobbek, H, Mainz, A, Suessmuth, R. | | 登録日 | 2023-01-24 | | 公開日 | 2023-06-14 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8CAR
 | | Discovery of the lanthipeptide Curvocidin and structural insights into its trifunctional synthetase CuvL | | 分子名称: | NITRATE ION, PHOSPHATE ION, Serine/threonine protein kinase | | 著者 | Martins, B.M, Sigurdsson, A, Duettmann, A.A, Jasyk, M, Dimos-Roehl, B, Schoepf, F, Gemander, M, Knittel, C.H, Schegotzki, R, Schmid, B, Kosol, S, Pommerening, L, Gonzalez-Viegas, M, Seidel, M, Huegelland, M, Leimkuehler, S, Dobbek, H, Mainz, A, Suessmuth, R. | | 登録日 | 2023-01-24 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL.
Angew.Chem.Int.Ed.Engl., 62, 2023
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5A4I
 | | The mechanism of Hydrogen activation by NiFE-hydrogenases | | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Evans, R.M, Brooke, E.J, Wehlin, S.A.M, Nomerotskaia, E, Sargent, F, Carr, S.C, Phillips, S.E.V, Armstrong, F.A. | | 登録日 | 2015-06-10 | | 公開日 | 2015-11-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | Mechanism of hydrogen activation by [NiFe] hydrogenases.
Nat. Chem. Biol., 12, 2016
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5A4F
 | | The mechanism of Hydrogen Activation by NiFe-hydrogenases. | | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... | | 著者 | Evans, R.M, Brooke, E.J, Wehlin, S.A.M, Nomerotskaia, E, Sargent, F, Carr, S.B, Phillips, S.E.V, Armstrong, F.A. | | 登録日 | 2015-06-09 | | 公開日 | 2015-11-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Mechanism of hydrogen activation by [NiFe] hydrogenases.
Nat. Chem. Biol., 12, 2016
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5ADU
 | | The Mechanism of Hydrogen Activation by NiFe-hydrogenases | | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Evans, R, Brooke, E.J, Wehlin, S.A, Nomerotskaia, E, Sargent, F, Carr, S.B, Phillips, S.E.V, Armstrong, F.A. | | 登録日 | 2015-08-24 | | 公開日 | 2015-11-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Mechanism of hydrogen activation by [NiFe] hydrogenases.
Nat. Chem. Biol., 12, 2016
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8U1E
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4UE3
 | | The Mechanism of Hydrogen Activation by NiFe-hydrogenases and the Importance of the active site Arginine | | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... | | 著者 | Evans, R.M, Wehlin, S.A.M, Nomerotskaia, E, Sargent, F, Carr, S.B, Phillips, S.E.V, Armstrong, F.A. | | 登録日 | 2014-12-15 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Mechanism of Hydrogen Activation by [Nife] Hydrogenases.
Nat.Chem.Biol., 12, 2016
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5FT2
 | | Sub-tomogram averaging of Lassa virus glycoprotein spike from virus- like particles at pH 5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRE-GLYCOPROTEIN POLYPROTEIN GP COMPLEX | | 著者 | Li, S, Zhaoyang, S, Pryce, R, Parsy, M.L, Fehling, S.K, Schlie, K, Siebert, C.A, Garten, W, Bowden, T.A, Strecker, T, Huiskonen, J.T. | | 登録日 | 2016-01-09 | | 公開日 | 2016-03-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (16.4 Å) | | 主引用文献 | Acidic Ph-Induced Conformations and Lamp1 Binding of the Lassa Virus Glycoprotein Spike.
Plos Pathog., 12, 2016
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5A4M
 | | Mechanism of Hydrogen activation by NiFe-hydrogenases | | 分子名称: | CHLORIDE ION, FE3-S4 CLUSTER, FE4-S3 CLUSTER, ... | | 著者 | Evans, R.M, Brooke, E.J, Wehlin, S.A.M, Nomerotskaia, E, Sergent, F, Carr, S.B, Philips, S.E.V, Armstrong, F.A. | | 登録日 | 2015-06-10 | | 公開日 | 2015-11-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism of Hydrogen Activation by [Nife] Hydrogenases.
Nat.Chem.Biol., 12, 2016
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5NZS
 | | The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor | | 分子名称: | ADP-ribosylation factor 1, ADP-ribosylation factor GTPase-activating protein 2, Coatomer subunit alpha, ... | | 著者 | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | | 登録日 | 2017-05-15 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (10.1 Å) | | 主引用文献 | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
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5NZR
 | | The structure of the COPI coat leaf | | 分子名称: | ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... | | 著者 | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | | 登録日 | 2017-05-15 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (9.2 Å) | | 主引用文献 | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
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8JBP
 | | Crystal structure of triosephosphate isomerase from Leishmania orientalis at 1.45 angstroms resolution with an arsenic atom bound at Cys57 | | 分子名称: | ARSENIC, Triosephosphate isomerase | | 著者 | Kuaprasert, B, Leartsakulpanich, U, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Robinson, R.C, Zhou, Y, Mungthin, M, Leelayoova, S, Saehlee, S, Choowongkomon, K. | | 登録日 | 2023-05-09 | | 公開日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Leishmania orientalis triosephosphate isomerase crystal structure at 1.45 angstroms resolution and its potential specific inhibitors
To be published
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1CT9
 | | CRYSTAL STRUCTURE OF ASPARAGINE SYNTHETASE B FROM ESCHERICHIA COLI | | 分子名称: | ADENOSINE MONOPHOSPHATE, ASPARAGINE SYNTHETASE B, CHLORIDE ION, ... | | 著者 | Larsen, T.M, Boehlein, S.K, Schuster, S.M, Richards, N.G.J, Thoden, J.B, Holden, H.M, Rayment, I. | | 登録日 | 1999-08-20 | | 公開日 | 1999-12-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structure of Escherichia coli asparagine synthetase B: a short journey from substrate to product.
Biochemistry, 38, 1999
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3MYU
 | | Mycoplasma genitalium MG289 | | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, ACETATE ION, High affinity transport system protein p37 | | 著者 | Sippel, K.H, Boehlein, S.K, Govindasamy, L, Namiki, K, Satai, Y, Quirit, J.G, Agbandje-McKenna, M, Goodison, S, Rosser, C.J, Sankaran, B, McKenna, R. | | 登録日 | 2010-05-11 | | 公開日 | 2010-10-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein.
Proteins, 79, 2011
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3ZYV
 | | Crystal structure of the mouse liver Aldehyde Oxidase 3 (mAOX3) | | 分子名称: | AOX3, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Trincao, J, Coelho, C, Mahro, M, Rodrigues, D, Terao, M, Garattini, E, Leimkuehler, S, Romao, M.J. | | 登録日 | 2011-08-27 | | 公開日 | 2012-09-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.545 Å) | | 主引用文献 | The First Mammalian Aldehyde Oxidase Crystal Structure: Insights Into Substrate Specificity.
J.Biol.Chem., 287, 2012
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3QO4
 | | The Crystal Structure of Death Receptor 6 | | 分子名称: | ACETATE ION, SULFATE ION, Tumor necrosis factor receptor superfamily member 21 | | 著者 | Kuester, M, Kemmerzehl, S, Dahms, S.O, Roeser, D, Than, M.E. | | 登録日 | 2011-02-09 | | 公開日 | 2011-05-18 | | 最終更新日 | 2012-02-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structure of death receptor 6 (DR6): a potential receptor of the amyloid precursor protein (APP).
J.Mol.Biol., 409, 2011
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1KL7
 | | Crystal Structure of Threonine Synthase from Yeast | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Threonine Synthase | | 著者 | Garrido-Franco, M, Ehlert, S, Messerschmidt, A, Marinkovic, S, Huber, R, Laber, B, Bourenkov, G.P, Clausen, T. | | 登録日 | 2001-12-11 | | 公開日 | 2002-04-24 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure and function of threonine synthase from yeast.
J.Biol.Chem., 277, 2002
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4NEJ
 | | Small molecular fragment bound to crystal contact interface of Interleukin-2 | | 分子名称: | 5-methylfuran-2-carboxylic acid, Interleukin-2 | | 著者 | Brenke, R, Jehle, S, Vajda, S, Allen, K.N, Kozakov, D. | | 登録日 | 2013-10-29 | | 公開日 | 2014-11-19 | | 実験手法 | X-RAY DIFFRACTION (1.919 Å) | | 主引用文献 | Small molecular fragments bound to binding energy hot-spot in crystal contact interface of Interleukin-2
To be Published
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2OVR
 | | Structure of the Skp1-Fbw7-CyclinEdegN complex | | 分子名称: | F-box/WD repeat protein 7, S-phase kinase-associated protein 1A, SULFATE ION, ... | | 著者 | Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P. | | 登録日 | 2007-02-14 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
Mol.Cell, 26, 2007
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2OVQ
 | | Structure of the Skp1-Fbw7-CyclinEdegC complex | | 分子名称: | F-box/WD repeat protein 7, S-phase kinase-associated protein 1A, SULFATE ION, ... | | 著者 | Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P. | | 登録日 | 2007-02-14 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
Mol.Cell, 26, 2007
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