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4NEM

Small molecular fragment bound to crystal contact interface of Interleukin-2

Summary for 4NEM
Entry DOI10.2210/pdb4nem/pdb
Related4NEJ
DescriptorInterleukin-2, 5-[(2,3-dichlorophenoxy)methyl]furan-2-carboxylic acid (3 entities in total)
Functional Keywordsfragment mapping, crystal contact, cytokine, interleukin-2, helixbundle, cd25, extracellular, immune system
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight15437.71
Authors
Jehle, S.,Brenke, R.,Vajda, S.,Allen, K.N.,Kozakov, D. (deposition date: 2013-10-29, release date: 2014-11-19)
Primary citationJehle, S.,Brenke, R.,Vajda, S.,Allen, K.N.,Kozakov, D.
Small molecular fragments bound to binding energy hot-spot in crystal contact interface of Interleukin-2
To be Published,
Experimental method
X-RAY DIFFRACTION (1.934 Å)
Structure validation

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