8CAV
Discovery of the lanthipeptide Curvocidin and structural insights into its trifunctional synthetase CuvL
Summary for 8CAV
Entry DOI | 10.2210/pdb8cav/pdb |
Descriptor | Serine/threonine protein kinase, CuvA, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total) |
Functional Keywords | lanthipeptide, biosynthetic protein |
Biological source | Thermomonospora curvata More |
Total number of polymer chains | 4 |
Total formula weight | 198434.05 |
Authors | Sigurdsson, A.,Martins, B.M.,Duettmann, S.A.,Jasyk, M.,Dimos-Roehl, B.,Schoepf, F.,Gemannter, M.,Knittel, C.H.,Schnegotyzki, R.,Schmid, B.,Kosol, S.,Gonzalez-Viegas, M.,Seidel, M.,Huegelland, M.,Leimkuehler, S.,Dobbek, H.,Mainz, A.,Suessmuth, R. (deposition date: 2023-01-24, release date: 2023-06-14) |
Primary citation | Sigurdsson, A.,Martins, B.M.,Duttmann, S.A.,Jasyk, M.,Dimos-Rohl, B.,Schopf, F.,Gemander, M.,Knittel, C.H.,Schnegotzki, R.,Schmid, B.,Kosol, S.,Pommerening, L.,Gonzales-Viegaz, M.,Seidel, M.,Hugelland, M.,Leimkuhler, S.,Dobbek, H.,Mainz, A.,Sussmuth, R.D. Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL. Angew.Chem.Int.Ed.Engl., 62:e202302490-e202302490, 2023 Cited by PubMed: 37014271DOI: 10.1002/anie.202302490 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.87 Å) |
Structure validation
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