8CAV
Discovery of the lanthipeptide Curvocidin and structural insights into its trifunctional synthetase CuvL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine protein kinase | polymer | 865 | 92965.0 | 2 | UniProt (D1A2F7) Pfam (PF00069) Pfam (PF05147) | Thermomonospora curvata | |
| 2 | C, D (D, G) | CuvA | polymer | 51 | 5485.2 | 2 | UniProt (D1A2F9) | Thermomonospora curvata | |
| 3 | E, F, I, K (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 4 | Chemie (MPD) | |||
| 4 | G, J (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 5 | H, L (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
D, G: -8 - 42 (UniProt: D1A2F9)
| PDB | External Database | Details |
|---|---|---|
| Ile 12 | Val 21 | conflict |
| Lys 13 | Pro 22 | conflict |
| Trp 14 | Ser 23 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 196900.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1533.7 | |
| All* | Total formula weight | 198434.0 |
