3ZYV

Crystal structure of the mouse liver Aldehyde Oxidase 3 (mAOX3)

Summary for 3ZYV

Entry DOI	10.2210/pdb3zyv/pdb
Descriptor	AOX3, SODIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... (7 entities in total)
Functional Keywords	oxidoreductase, molybdenum cofactor
Biological source	MUS MUSCULUS (HOUSE MOUSE)
Total number of polymer chains	4
Total formula weight	595231.61
Authors	Trincao, J.,Coelho, C.,Mahro, M.,Rodrigues, D.,Terao, M.,Garattini, E.,Leimkuehler, S.,Romao, M.J. (deposition date: 2011-08-27, release date: 2012-09-05, Last modification date: 2023-12-20)
Primary citation	Coelho, C.,Mahro, M.,Trincao, J.,Carvalho, A.T.P.,Ramos, M.J.,Terao, M.,Garattini, E.,Leimkuhler, S.,Romao, M.J. The First Mammalian Aldehyde Oxidase Crystal Structure: Insights Into Substrate Specificity. J.Biol.Chem., 287:40690-, 2012 Cited by PubMed Abstract: Aldehyde oxidases have pharmacological relevance, and AOX3 is the major drug-metabolizing enzyme in rodents. PubMed: 23019336 DOI: 10.1074/JBC.M112.390419 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.545 Å)

Structure validation