4R21
 
 | | Zebra fish cytochrome P450 17A2 with Progesterone | | 分子名称: | Cytochrome P450 family 17 polypeptide 2, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2014-08-08 | | 公開日 | 2014-12-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2.
J.Biol.Chem., 290, 2015
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4R1Z
 | | Zebra fish cytochrome P450 17A1 with Abiraterone | | 分子名称: | Abiraterone, Cyp17a1 protein, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2014-08-08 | | 公開日 | 2014-12-31 | | 最終更新日 | 2015-03-04 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2.
J.Biol.Chem., 290, 2015
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3P4D
 | | Alternatingly modified 2'Fluoro RNA octamer f/rC4G4 | | 分子名称: | 5'-R(*(CFZ)P*CP*(CFZ)P*CP*(GF2)P*GP*(GF2)P*G)-3' | | 著者 | Pallan, P.S, Greene, E.M, Jicman, P.A, Pandey, R.K, Manoharan, M, Rozners, E, Egli, M. | | 登録日 | 2010-10-06 | | 公開日 | 2011-01-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA.
Nucleic Acids Res., 39, 2011
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5L1I
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4HUG
 | | Structure of 5-chlorouracil modified A:U base pairs | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*CP*GP*AP*AP*(UCL)P*(UCL)P*CP*GP*CP*G)-3'), GLYCEROL, ... | | 著者 | Patra, A, Egli, M. | | 登録日 | 2012-11-02 | | 公開日 | 2012-12-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs.
Nucleic Acids Res., 41, 2013
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389D
 | | CRYSTAL STRUCTURE OF B-DNA WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINES: IMPLICATIONS OF CONFORMATIONAL PREORGANIZATION FOR DUPLEX STABILITY | | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | | 著者 | Berger, I, Tereshko, V, Ikeda, H, Marquez, V.E, Egli, M. | | 登録日 | 1998-04-20 | | 公開日 | 1998-05-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability.
Nucleic Acids Res., 26, 1998
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5VBU
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5DER
 | | RNA oligonucleotide containing (R)-C5'-ME-2'F U | | 分子名称: | RNA oligonucleotide containing (R)-C5'-Me-2'-FU | | 著者 | Harp, J.M, Egli, M. | | 登録日 | 2015-08-25 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides.
J.Org.Chem., 81, 2016
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5DEK
 | | RNA octamer containing dT | | 分子名称: | COBALT HEXAMMINE(III), RNA oligonucleotide containing dT | | 著者 | Harp, J.M, Egli, M. | | 登録日 | 2015-08-25 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.993 Å) | | 主引用文献 | Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides.
J.Org.Chem., 81, 2016
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5D8T
 | | RNA octamer containing (S)-5' methyl, 2'-F U. | | 分子名称: | COBALT HEXAMMINE(III), RNA oligonucleotide containing (S)-C5'-Me-2'-FU | | 著者 | Harp, J.M, Egli, M. | | 登録日 | 2015-08-17 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides.
J.Org.Chem., 81, 2016
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5DO4
 | | Thrombin-RNA aptamer complex | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2015-09-10 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.859 Å) | | 主引用文献 | Evoking picomolar binding in RNA by a single phosphorodithioate linkage.
Nucleic Acids Res., 44, 2016
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437D
 | | CRYSTAL STRUCTURE OF AN RNA PSEUDOKNOT FROM BEET WESTERN YELLOW VIRUS INVOLVED IN RIBOSOMAL FRAMESHIFTING | | 分子名称: | MAGNESIUM ION, RNA PSEUDOKNOT, SODIUM ION | | 著者 | Su, L, Chen, L, Egli, M, Berger, J.M, Rich, A. | | 登録日 | 1998-11-24 | | 公開日 | 1998-12-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot.
Nat.Struct.Biol., 6, 1999
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4HQI
 | | Structure of O6-Benzyl-2'-deoxyguanosine opposite perimidinone-derived synthetic nucleoside in DNA duplex | | 分子名称: | SPERMINE, STRONTIUM ION, Short modified nucleic acids | | 著者 | Kowal, E.A, Lad, R, Pallan, P.S, Muffly, E, Wawrzak, Z, Egli, M, Sturla, S.J, Stone, M.P. | | 登録日 | 2012-10-25 | | 公開日 | 2013-07-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Recognition of O6-benzyl-2'-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction.
Nucleic Acids Res., 41, 2013
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1U9I
 | | Crystal Structure of Circadian Clock Protein KaiC with Phosphorylation Sites | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, KaiC, MAGNESIUM ION | | 著者 | Xu, Y, Mori, T, Pattanayek, R, Pattanayek, S, Egli, M, Johnson, C.H. | | 登録日 | 2004-08-09 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Identification of key phosphorylation sites in the circadian clock protein KaiC by crystallographic and mutagenetic analyses
PROC.NATL.ACAD.SCI.USA, 101, 2004
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4RBY
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4RC0
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4RBZ
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1TF7
 | | Crystal Structure of Circadian Clock Protein KaiC | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, KaiC | | 著者 | Pattanayek, R, Wang, J, Mori, T, Xu, Y, Johnson, C.H, Egli, M. | | 登録日 | 2004-05-26 | | 公開日 | 2004-08-24 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Visualizing a Circadian Clock Protein; Crystal Structure of KaiC and Functional Insights
Mol.Cell, 15, 2004
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2QKE
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1RXB
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4RUA
 | | Crystal structure of Y-family DNA polymerase Dpo4 bypassing a MeFapy-dG adduct | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase IV, ... | | 著者 | Patra, A, Banerjee, S, Stone, M.P, Egli, M. | | 登録日 | 2014-11-18 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV.
J.Am.Chem.Soc., 137, 2015
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4RU9
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4F2X
 | | Structure of 3'-Fluoro Cyclohexenyl Nucleic Acid Heptamer | | 分子名称: | 5'-D(*CP*GP*CP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*(XTF)P*GP*CP*G)-3', COBALT (III) ION, ... | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2012-05-08 | | 公開日 | 2012-05-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Synthesis and Antisense Properties of Fluoro Cyclohexenyl Nucleic Acid (F-CeNA), a Nuclease Stable Mimic of 2'-Fluoro RNA.
J.Org.Chem., 77, 2012
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4RUC
 | | Crystal structure of Y-family DNA polymerase Dpo4 extending from a MeFapy-dG:dC pair | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase IV, ... | | 著者 | Patra, A, Banerjee, S, Stone, M.P, Egli, M. | | 登録日 | 2014-11-18 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV.
J.Am.Chem.Soc., 137, 2015
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2GUN
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