3P4D

Alternatingly modified 2'Fluoro RNA octamer f/rC4G4

Summary for 3P4D

• Entry DOI: 10.2210/pdb3p4d/pdb
• Related: 3P4B 3P4C
• Descriptor: 5'-R(*(CFZ)P*CP*(CFZ)P*CP*(GF2)P*GP*(GF2)P*G)-3' (2 entities in total)
• Functional Keywords: rna, 2'-fluoro-rna, o2'-modification, octamer, 2'-fluoro 2'-deoxycytidine, 2'-fluoro 2'-deoxyguanosine, sirna
• Total number of polymer chains: 2
• Total formula weight: 5129.11

Authors

Pallan, P.S.,Greene, E.M.,Jicman, P.A.,Pandey, R.K.,Manoharan, M.,Rozners, E.,Egli, M. (deposition date: 2010-10-06, release date: 2011-01-05, Last modification date: 2023-09-06)

• Primary citation: Pallan, P.S.,Greene, E.M.,Jicman, P.A.,Pandey, R.K.,Manoharan, M.,Rozners, E.,Egli, M.; Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA.; Nucleic Acids Res., 39:3482-3495, 2011; PubMed: 21183463; DOI: 10.1093/nar/gkq1270

Experimental method

X-RAY DIFFRACTION (1.85 Å)