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5DER

RNA oligonucleotide containing (R)-C5'-ME-2'F U

Summary for 5DER
Entry DOI10.2210/pdb5der/pdb
Related5DEK
DescriptorRNA oligonucleotide containing (R)-C5'-Me-2'-FU (2 entities in total)
Functional Keywordsrna, oligonucleotide
Biological sourcesynthetic construct
Total number of polymer chains4
Total formula weight10170.32
Authors
Harp, J.M.,Egli, M. (deposition date: 2015-08-25, release date: 2016-06-29, Last modification date: 2024-03-06)
Primary citationKel In, A.V.,Zlatev, I.,Harp, J.,Jayaraman, M.,Bisbe, A.,O Shea, J.,Taneja, N.,Manoharan, R.M.,Khan, S.,Charisse, K.,Maier, M.A.,Egli, M.,Rajeev, K.G.,Manoharan, M.
Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides.
J.Org.Chem., 81:2261-2279, 2016
Cited by
PubMed: 26940174
DOI: 10.1021/acs.joc.5b02375
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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