4DIQ
 
 | | Crystal Structure of human NO66 | | 分子名称: | Lysine-specific demethylase NO66, NICKEL (II) ION, PYRIDINE-2,4-DICARBOXYLIC ACID, ... | | 著者 | Vollmar, M, Krojer, T, Ng, S, Pilka, E, Bray, J, Pike, A.C.W, Filippakopoulos, P, Roos, A, Arrowsmith, C.H, Edwards, E, Bountra, C, von Delft, F, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2012-01-31 | | 公開日 | 2012-03-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of human NO66
TO BE PUBLISHED
|
|
5AMF
 | | Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment Ethyl 4,5,6,7- tetrahydro-1H-indazole-5-carboxylate (SGC - Diamond I04-1 fragment screening) | | 分子名称: | BROMODOMAIN-CONTAINING PROTEIN 1, ETHYL (5R)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE-5-CARBOXYLATE, SODIUM ION | | 著者 | Pearce, N.M, Fairhead, M, Strain-Damerell, C, Talon, R, Wright, N, Ng, J.T, Bradley, A, Cox, O, Bowkett, D, Collins, P, Brandao-Neto, J, Douangamath, A, Krojer, T, Burgess-Brown, N, Brennan, P, Arrowsmith, C.H, Edwards, E, Bountra, C, von Delft, F. | | 登録日 | 2015-03-10 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal Structure of the Bromodomain of Human Surface Epitope Engineered Brd1A in Complex with 3D Consortium Fragment Ethyl 4,5,6,7-Tetrahydro-1H-Indazole-5-Carboxylate
To be Published
|
|
5AME
 | | Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment 4-acetyl- piperazin-2-one (SGC - Diamond I04-1 fragment screening) | | 分子名称: | 4-acetyl-piperazin-2-one, BROMODOMAIN-CONTAINING PROTEIN 1, SODIUM ION | | 著者 | Pearce, N.M, Fairhead, M, Strain-Damerell, C, Talon, R, Wright, N, Ng, J.T, Bradley, A, Cox, O, Bowkett, D, Collins, P, Brandao-Neto, J, Douangamath, A, Krojer, T, Burgess-Brown, N, Brennan, P, Arrowsmith, C.H, Edwards, E, Bountra, C, von Delft, F. | | 登録日 | 2015-03-10 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.578 Å) | | 主引用文献 | Crystal Structure of the Bromodomain of Human Surface Epitope Engineered Brd1A in Complex with 3D Consortium Fragment 4-Acetyl-Piperazin-2-One
To be Published
|
|
3UMG
 | | Crystal Structure of the Defluorinating L-2-Haloacid Dehalogenase Rha0230 | | 分子名称: | CHLORIDE ION, Haloacid dehalogenase | | 著者 | Chan, P.W.Y, Savchenko, A, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-11-13 | | 公開日 | 2012-11-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural adaptations of L-2-haloacid dehalogenases that enable hydrolytic defluorination
To be Published
|
|
6GMC
 | | 1.2 A resolution structure of human hydroxyacid oxidase 1 bound with FMN and 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole | | 分子名称: | 1,2-ETHANEDIOL, 5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylate, FLAVIN MONONUCLEOTIDE, ... | | 著者 | MacKinnon, S, Bezerra, G.A, Krojer, T, Smee, C, Arrowsmith, C.H, Edwards, E, Bountra, C, Oppermann, U, Brennan, P.E, Yue, W.W. | | 登録日 | 2018-05-24 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate
To Be Published
|
|
3UM9
 | | Crystal Structure of the Defluorinating L-2-Haloacid Dehalogenase Bpro0530 | | 分子名称: | Haloacid dehalogenase, type II, NICKEL (II) ION, ... | | 著者 | Chan, P.W.Y, Savchenko, A, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-11-12 | | 公開日 | 2012-11-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structural adaptations of L-2-haloacid dehalogenases that enable hydrolytic defluorination
To be Published
|
|
6GMB
 | | Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, GLYCOLIC ACID, ... | | 著者 | MacKinnon, S, Bezerra, G.A, Krojer, T, Smee, C, Arrowsmith, C.H, Edwards, E, Bountra, C, Oppermann, U, Brennan, P.E, Yue, W.W, Structural Genomics Consortium (SGC) | | 登録日 | 2018-05-24 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate
To Be Published
|
|
3UMC
 | | Crystal Structure of the L-2-Haloacid Dehalogenase PA0810 | | 分子名称: | CHLORIDE ION, SODIUM ION, haloacid dehalogenase | | 著者 | Petit, P, Chan, P.W.Y, Savchenko, A, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-11-13 | | 公開日 | 2012-11-14 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural adaptations of L-2-haloacid dehalogenases that enable hydrolytic defluorination
To be Published
|
|
3UMB
 | | Crystal Structure of the L-2-Haloacid Dehalogenase RSc1362 | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, POTASSIUM ION, ... | | 著者 | Petit, P, Chan, P.W.Y, Savchenko, A, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-11-12 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural adaptations of L-2-haloacid dehalogenases that enable hydrolytic defluorination
To be Published
|
|
3R3Y
 | | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn/Fluoroacetate | | 分子名称: | CALCIUM ION, CHLORIDE ION, Fluoroacetate dehalogenase | | 著者 | Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-03-16 | | 公開日 | 2011-05-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Mapping the reaction coordinates of enzymatic defluorination.
J.Am.Chem.Soc., 133, 2011
|
|
3R3U
 | | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT/apo | | 分子名称: | CHLORIDE ION, Fluoroacetate dehalogenase, NICKEL (II) ION | | 著者 | Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-03-16 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Mapping the reaction coordinates of enzymatic defluorination.
J.Am.Chem.Soc., 133, 2011
|
|
3R41
 | | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn/apo | | 分子名称: | CALCIUM ION, CHLORIDE ION, Fluoroacetate dehalogenase | | 著者 | Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-03-17 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Mapping the reaction coordinates of enzymatic defluorination.
J.Am.Chem.Soc., 133, 2011
|
|
3R3W
 | | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Chloroacetate | | 分子名称: | CALCIUM ION, CHLORIDE ION, Fluoroacetate dehalogenase, ... | | 著者 | Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-03-16 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Mapping the reaction coordinates of enzymatic defluorination.
J.Am.Chem.Soc., 133, 2011
|
|
3R3V
 | | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Fluoroacetate | | 分子名称: | CALCIUM ION, CHLORIDE ION, Fluoroacetate dehalogenase, ... | | 著者 | Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-03-16 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Mapping the reaction coordinates of enzymatic defluorination.
J.Am.Chem.Soc., 133, 2011
|
|
3R3Z
 | | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT/Glycolate | | 分子名称: | Fluoroacetate dehalogenase, GLYCOLIC ACID, NICKEL (II) ION | | 著者 | Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-03-16 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mapping the reaction coordinates of enzymatic defluorination.
J.Am.Chem.Soc., 133, 2011
|
|
3R40
 | | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/apo | | 分子名称: | CALCIUM ION, CHLORIDE ION, Fluoroacetate dehalogenase | | 著者 | Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-03-16 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Mapping the reaction coordinates of enzymatic defluorination.
J.Am.Chem.Soc., 133, 2011
|
|
3R3X
 | | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Bromoacetate | | 分子名称: | CALCIUM ION, CHLORIDE ION, Fluoroacetate dehalogenase, ... | | 著者 | Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-03-16 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mapping the reaction coordinates of enzymatic defluorination.
J.Am.Chem.Soc., 133, 2011
|
|
1ZEG
 | | STRUCTURE OF B28 ASP INSULIN IN COMPLEX WITH PHENOL | | 分子名称: | CHLORIDE ION, INSULIN, PHENOL, ... | | 著者 | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | | 登録日 | 1998-05-01 | | 公開日 | 1998-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
|
|
1ZEI
 | | CROSS-LINKED B28 ASP INSULIN | | 分子名称: | CHLORIDE ION, INSULIN, M-CRESOL, ... | | 著者 | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | | 登録日 | 1998-07-14 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
|
|
1ZEH
 | | STRUCTURE OF INSULIN | | 分子名称: | CHLORIDE ION, INSULIN, M-CRESOL, ... | | 著者 | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | | 登録日 | 1998-05-01 | | 公開日 | 1998-12-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
|
|
2A9U
 | | Structure of the N-terminal domain of Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8) | | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 8 | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, E, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-07-12 | | 公開日 | 2005-08-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
|
|
