6GMC

1.2 A resolution structure of human hydroxyacid oxidase 1 bound with FMN and 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole

Summary for 6GMC

Related2NZL 6GMB
DescriptorHydroxyacid oxidase 1, 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, ... (5 entities in total)
Functional Keywordsglycolate, glyoxylate, peroxisome, fmn, primary hyperoxaluria, oxidoreductase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight41710.26
Authors
MacKinnon, S.,Bezerra, G.A.,Krojer, T.,Smee, C.,Arrowsmith, C.H.,Edwards, E.,Bountra, C.,Oppermann, U.,Brennan, P.E.,Yue, W.W. (deposition date: 2018-05-24, release date: 2018-06-13, Last modification date: 2018-06-27)
Primary citation
MacKinnon, S.,Bezerra, G.A.,Krojer, T.,Smee, C.,Arrowsmith, C.H.,Edwards, E.,Bountra, C.,Oppermann, U.,Brennan, P.E.,Yue, W.W.
Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.1621002.4%7.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report