6Z1F
 
 | | CryoEM structure of Rubisco Activase with its substrate Rubisco from Nostoc sp. (strain PCC7120) | | Descriptor: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Wang, H, Bracher, A, Flecken, M, Popilka, L, Hartl, F.U, Hayer-Hartl, M. | | Deposit date: | 2020-05-13 | | Release date: | 2020-09-23 | | Last modified: | 2021-04-07 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes.
Cell, 183, 2020
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5A1U
 | | The structure of the COPI coat triad | | Descriptor: | ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ... | | Authors: | Dodonova, S.O, Diestelkoetter-Bachert, P, von Appen, A, Hagen, W.J.H, Beck, R, Beck, M, Wieland, F, Briggs, J.A.G. | | Deposit date: | 2015-05-06 | | Release date: | 2015-07-08 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (13 Å) | | Cite: | Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
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5ABS
 | | CRYSTAL STRUCTURE OF THE C-TERMINAL COILED-COIL DOMAIN OF CIN85 IN SPACE GROUP P321 | | Descriptor: | SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1, ZINC ION | | Authors: | Wong, L, Habeck, M, Griesinger, C, Becker, S. | | Deposit date: | 2015-08-07 | | Release date: | 2016-07-13 | | Last modified: | 2019-02-06 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | The Adaptor Protein Cin85 Assembles Intracellular Signaling Clusters for B Cell Activation.
Sci.Signal., 9, 2016
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6GJU
 | | human NBD1 of CFTR in complex with nanobodies T2a and T4 | | Descriptor: | Cystic fibrosis transmembrane conductance regulator, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. | | Deposit date: | 2018-05-17 | | Release date: | 2019-06-26 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
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5A1W
 | | The structure of the COPI coat linkage II | | Descriptor: | ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ... | | Authors: | Dodonova, S.O, Diestelkoetter-Bachert, P, von Appen, A, Hagen, W.J.H, Beck, R, Beck, M, Wieland, F, Briggs, J.A.G. | | Deposit date: | 2015-05-06 | | Release date: | 2015-07-08 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (18 Å) | | Cite: | Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
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6Z47
 | | Smooth muscle myosin shutdown state heads region | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin heavy chain 11, ... | | Authors: | Scarff, C.A, Carrington, G, Casas Mao, D, Chalovich, J.M, Knight, P.J, Ranson, N.A, Peckham, M. | | Deposit date: | 2020-05-22 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (6.3 Å) | | Cite: | Structure of the shutdown state of myosin-2.
Nature, 588, 2020
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6GJS
 | | Human NBD1 of CFTR in complex with nanobodies D12 and T4 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ... | | Authors: | Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. | | Deposit date: | 2018-05-16 | | Release date: | 2019-06-26 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
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5UAM
 | | Structure of a new family of Polysaccharide lyase PL25-Ulvanlyase. | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | | Authors: | Ulaganathan, T.S, Boniecki, M.T, Cygler, M. | | Deposit date: | 2016-12-19 | | Release date: | 2017-03-29 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture.
ACS Chem. Biol., 12, 2017
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5UF5
 | | Structure of the effector protein SidK (lpg0968) from Legionella pneumophila (domain-swapped dimer) | | Descriptor: | GLYCEROL, effector protein SidK | | Authors: | Beyrakhova, K, Xu, C, Boniecki, M.T, Cygler, M. | | Deposit date: | 2017-01-03 | | Release date: | 2017-05-10 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
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1U36
 | | Crystal structure of WLAC mutant of dimerisation domain of NF-kB p50 transcription factor | | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | Deposit date: | 2004-07-21 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
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1U41
 | | Crystal structure of YLGV mutant of dimerisation domain of NF-kB p50 transcription factor | | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | Deposit date: | 2004-07-23 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.202 Å) | | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
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1U3Y
 | | Crystal structure of ILAC mutant of dimerisation domain of NF-kB p50 transcription factor | | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | Deposit date: | 2004-07-22 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
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1U42
 | | Crystal structure of MLAM mutant of dimerisation domain of NF-kB p50 transcription factor | | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | Deposit date: | 2004-07-23 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.699 Å) | | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
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1U3Z
 | | Crystal structure of MLAC mutant of dimerisation domain of NF-kB p50 transcription factor | | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | Deposit date: | 2004-07-23 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
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6RUL
 | | Crystal structure of GFP-LAMA-F98 - a GFP enhancer nanobody with cpDHFR insertion and TMP and NADPH | | Descriptor: | GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRIETHYLENE GLYCOL, ... | | Authors: | Farrants, H, Tarnawski, M, Mueller, T.G, Otsuka, S, Hiblot, J, Koch, B, Kueblbeck, M, Kraeusslich, H.-G, Ellenberg, J, Johnsson, K. | | Deposit date: | 2019-05-28 | | Release date: | 2020-02-12 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Chemogenetic Control of Nanobodies.
Nat.Methods, 17, 2020
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1YBJ
 | | Structural and Dynamics studies of both apo and holo forms of the hemophore HasA | | Descriptor: | Hemophore HasA | | Authors: | Wolff, N, Izadi-Pruneyre, N, Couprie, J, Habeck, M, Linge, J, Rieping, W, Wandersman, C, Nilges, M, Delepierre, M, Lecroisey, A. | | Deposit date: | 2004-12-21 | | Release date: | 2005-12-27 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Comparative analysis of structural and dynamic properties of the loaded and unloaded hemophore HasA: functional implications.
J.Mol.Biol., 376, 2008
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6RUM
 | | Crystal structure of GFP-LAMA-G97 - a GFP enhancer nanobody with cpDHFR insertion and TMP and NADPH | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GFP-LAMA-G97 a GFP enhancer nanobody with cpDHFR insertion, ... | | Authors: | Farrants, H, Tarnawski, M, Mueller, T.G, Otsuka, S, Hiblot, J, Koch, B, Kueblbeck, M, Kraeusslich, H.-G, Ellenberg, J, Johnsson, K. | | Deposit date: | 2019-05-28 | | Release date: | 2020-02-12 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Chemogenetic Control of Nanobodies.
Nat.Methods, 17, 2020
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5UFK
 | | Structure of the effector protein SidK (lpg0968) from Legionella pneumophila | | Descriptor: | GLYCEROL, effector protein SidK | | Authors: | Beyrakhova, K, Xu, C, Boniecki, M.T, Cygler, M. | | Deposit date: | 2017-01-04 | | Release date: | 2017-05-10 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
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1U3J
 | | Crystal structure of MLAV mutant of dimerisation domain of NF-kB p50 transcription factor | | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | Deposit date: | 2004-07-22 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
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6Z1G
 | | CryoEM structure of the interaction between Rubisco Activase small-subunit-like (SSUL) domain with Rubisco from Nostoc sp. (strain PCC7120) | | Descriptor: | Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain, Ribulose bisphosphate carboxylase/oxygenase activase | | Authors: | Wang, H, Bracher, A, Flecken, M, Popilka, L, Hartl, F.U, Hayer-Hartl, M. | | Deposit date: | 2020-05-13 | | Release date: | 2020-09-23 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (8.2 Å) | | Cite: | Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes.
Cell, 183, 2020
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5A9Q
 | | Human nuclear pore complex | | Descriptor: | NUCLEAR PORE COMPLEX PROTEIN NUP107, NUCLEAR PORE COMPLEX PROTEIN NUP133, NUCLEAR PORE COMPLEX PROTEIN NUP155, ... | | Authors: | von Appen, A, Kosinski, J, Sparks, L, Ori, A, DiGuilio, A, Vollmer, B, Mackmull, M, Banterle, N, Parca, L, Kastritis, P, Buczak, K, Mosalaganti, S, Hagen, W, Andres-Pons, A, Lemke, E.A, Bork, P, Antonin, W, Glavy, J.S, Bui, K.H, Beck, M. | | Deposit date: | 2015-07-22 | | Release date: | 2015-09-30 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (23 Å) | | Cite: | In Situ Structural Analysis of the Human Nuclear Pore Complex
Nature, 526, 2015
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2RGU
 | | Crystal structure of complex of human DPP4 and inhibitor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-d ione, Dipeptidyl peptidase 4 | | Authors: | Nar, H, Himmelsbach, F, Eckhardt, M. | | Deposit date: | 2007-10-05 | | Release date: | 2007-11-06 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | 8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes.
J.Med.Chem., 50, 2007
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2RSY
 | | Solution structure of the SH2 domain of Csk in complex with a phosphopeptide from Cbp | | Descriptor: | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Tyrosine-protein kinase CSK | | Authors: | Tanaka, H, Akagi, K, Oneyama, C, Tanaka, M, Sasaki, Y, Kanou, T, Lee, Y, Yokogawa, D, Debenecker, M, Nakagawa, A, Okada, M, Ikegami, T. | | Deposit date: | 2012-09-10 | | Release date: | 2013-04-10 | | Last modified: | 2019-12-25 | | Method: | SOLUTION NMR | | Cite: | Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains.
J.Biol.Chem., 288, 2013
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6ENT
 | | Structure of the rat RKIP variant delta143-146 | | Descriptor: | CHLORIDE ION, Phosphatidylethanolamine-binding protein 1, ZINC ION | | Authors: | Koelmel, W, Hirschbeck, M, Schindelin, H, Lorenz, K, Kisker, C. | | Deposit date: | 2017-10-06 | | Release date: | 2017-12-13 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.66 Å) | | Cite: | Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2GZU
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