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PDB: 641 件
9EST
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BU of 9est by Molmil
STRUCTURAL STUDY OF PORCINE PANCREATIC ELASTASE COMPLEXED WITH 7-AMINO-3-(2-BROMOETHOXY)-4-CHLOROISOCOUMARIN AS A NONREACTIVATABLE DOUBLY COVALENT ENZYME-INHIBITOR COMPLEX
分子名称: (2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATE, CALCIUM ION, PORCINE PANCREATIC ELASTASE, ...
著者Radhakrishnan, R, Powers, J.C, Meyer Jr, E.F.
登録日1991-01-14
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural study of porcine pancreatic elastase complexed with 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin as a nonreactivatable doubly covalent enzyme-inhibitor complex.
Biochemistry, 30, 1991
4VGC
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BU of 4vgc by Molmil
GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
分子名称: D-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION
著者Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F.
登録日1997-05-01
公開日1997-11-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
3ZWU
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BU of 3zwu by Molmil
Pseudomonas fluorescens PhoX in complex with vanadate, a transition state analogue
分子名称: ALKALINE PHOSPHATASE PHOX, CALCIUM ION, CHLORIDE ION, ...
著者Yong, S.C, Roversi, P, Lillington, J.E.D, Zeldin, O.B, Garman, E.F, Lea, S.M, Berks, B.C.
登録日2011-08-02
公開日2012-08-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献A Complex Iron-Calcium Cofactor Catalyzing Phosphotransfer Chemistry
Science, 345, 2014
5FMJ
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BU of 5fmj by Molmil
Bcl-xL with mouse Bak BH3 Q75L complex
分子名称: 1,2-ETHANEDIOL, BAK1 PROTEIN, BCL-2-LIKE PROTEIN 1
著者Fairlie, W.D, Lee, E.F, Smith, B.J.
登録日2015-11-06
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Physiological Restraint of Bak by Bcl-Xl is Essential for Cell Survival.
Genes Dev., 30, 2016
5GRT
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BU of 5grt by Molmil
HUMAN GLUTATHIONE REDUCTASE A34E, R37W MUTANT, GLUTATHIONYLSPERMIDINE COMPLEX
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, GLUTATHIONYLSPERMIDINE DISULFIDE
著者Stoll, V.S, Simpson, S.J, Krauth-Siegel, R.L, Walsh, C.T, Pai, E.F.
登録日1997-02-12
公開日1997-08-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity.
Biochemistry, 36, 1997
6P43
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BU of 6p43 by Molmil
Yeast cytochrome c peroxidase in complex with iso-1 cytochrome c (Y48K)
分子名称: Cytochrome c iso-1, Cytochrome c peroxidase, mitochondrial, ...
著者Yee, E.F, Crane, B.R.
登録日2019-05-25
公開日2019-10-23
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (1.913 Å)
主引用文献Tuning Radical Relay Residues by Proton Management Rescues Protein Electron Hopping.
J.Am.Chem.Soc., 141, 2019
6P42
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BU of 6p42 by Molmil
Yeast cytochrome c peroxidase (W191Y:L232H) in complex with iso-1 cytochrome c
分子名称: Cytochrome c iso-1, Cytochrome c peroxidase, mitochondrial, ...
著者Yee, E.F, Crane, B.R.
登録日2019-05-25
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.905 Å)
主引用文献Tuning Radical Relay Residues by Proton Management Rescues Protein Electron Hopping.
J.Am.Chem.Soc., 141, 2019
3EST
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BU of 3est by Molmil
STRUCTURE OF NATIVE PORCINE PANCREATIC ELASTASE AT 1.65 ANGSTROMS RESOLUTION
分子名称: CALCIUM ION, PORCINE PANCREATIC ELASTASE, SULFATE ION
著者Meyer, E.F, Cole, G, Radhakrishnan, R, Epp, O.
登録日1987-09-17
公開日1988-01-16
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of native porcine pancreatic elastase at 1.65 A resolutions.
Acta Crystallogr.,Sect.B, 44, 1988
6C94
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BU of 6c94 by Molmil
Structure Of Cytochrome P450 4B1 (CYP4B1) Complexed with the Inhibitor HET0016
分子名称: Cytochrome P450 4B1, N-(4-butyl-2-methylphenyl)-N'-hydroxyimidoformamide, PROTOPORPHYRIN IX CONTAINING FE
著者Hsu, M.-H, Johnson, E.F.
登録日2018-01-25
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1.
J. Biol. Chem., 293, 2018
6C93
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Effects of the E310A Mutation of Cytochrome P450 4B1 (CYP4B1) on n-Octane binding and Heme Ruffling
分子名称: Cytochrome P450 4B1, N-OCTANE, PROTOPORPHYRIN IX CONTAINING FE
著者Hsu, M.-H, Johnson, E.F.
登録日2018-01-25
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.674 Å)
主引用文献Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1.
J. Biol. Chem., 293, 2018
8EST
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BU of 8est by Molmil
REACTION OF PORCINE PANCREATIC ELASTASE WITH 7-SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS: DESIGN OF POTENT INHIBITORS USING THE CRYSTAL STRUCTURE OF THE COMPLEX FORMED WITH 4-CHLORO-3-ETHOXY-7-GUANIDINO-ISOCOUMARIN
分子名称: CALCIUM ION, ETHYL-(2-CARBOXY-4-GUANIDINIUM-PHENYL)-CHLOROACETATE, PORCINE PANCREATIC ELASTASE, ...
著者Radhakrishnan, R, Powers, J.C, Meyerjunior, E.F.
登録日1990-02-21
公開日1992-10-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Reaction of porcine pancreatic elastase with 7-substituted 3-alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3-ethoxy-7-guanidinoisocoumarin.
Biochemistry, 29, 1990
2IHY
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BU of 2ihy by Molmil
Structure of the Staphylococcus aureus putative ATPase subunit of an ATP-binding cassette (ABC) transporter
分子名称: ABC transporter, ATP-binding protein, SULFATE ION
著者McGrath, T.E, Yu, C.S, Romanov, V, Lam, R, Dharamsi, A, Virag, C, Mansoury, K, Thambipillai, D, Richards, D, Guthrie, J, Edwards, A.M, Pai, E.F, Chirgadze, N.Y.
登録日2006-09-27
公開日2007-09-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the Staphylococcus aureus putative ATPase subunit of an ATP-binding cassette (ABC) transporter
To be Published
6W9N
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BU of 6w9n by Molmil
Solution structure of the FYVE domain of ALFY
分子名称: WD repeat and FYVE domain-containing protein 3, ZINC ION
著者Reinhart, E.F, Pellegrini, M, Ragusa, M.J.
登録日2020-03-23
公開日2020-12-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A highly conserved glutamic acid in ALFY inhibits membrane binding to aid in aggregate clearance.
Traffic, 22, 2021
6DCN
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BU of 6dcn by Molmil
Bcl-xL complex with Beclin 1 BH3 domain T108pThr
分子名称: BCL-xl protein, Beclin-1
著者Lee, E.F, Smith, B.J, Smith, N.A, Yao, S, Fairlie, W.D.
登録日2018-05-07
公開日2018-05-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.444 Å)
主引用文献Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.
Autophagy, 15, 2019
6DL7
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BU of 6dl7 by Molmil
Human mitochondrial ClpP in complex with ONC201 (TIC10)
分子名称: 7-benzyl-4-[(2-methylphenyl)methyl]-6,7,8,9-tetrahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one, ATP-dependent Clp protease proteolytic subunit, mitochondrial
著者Halgas, O, Zarabi, S.F, Schimmer, A, Pai, E.F.
登録日2018-05-31
公開日2019-05-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.
Cancer Cell, 35, 2019
6DCO
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BU of 6dco by Molmil
Bcl-xL complex with Beclin 1 BH3 domain T108D
分子名称: Bcl-2-like protein 1,Bcl-2-like protein 1, Beclin-1, CHLORIDE ION
著者Lee, E.F, Smith, B.J, Smith, N.A, Yao, S, Fairlie, W.D.
登録日2018-05-07
公開日2018-05-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.
Autophagy, 15, 2019
5P21
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BU of 5p21 by Molmil
REFINED CRYSTAL STRUCTURE OF THE TRIPHOSPHATE CONFORMATION OF H-RAS P21 AT 1.35 ANGSTROMS RESOLUTION: IMPLICATIONS FOR THE MECHANISM OF GTP HYDROLYSIS
分子名称: C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Pai, E.F, Wittinghofer, A, Kabsch, W.
登録日1990-04-30
公開日1992-01-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.
EMBO J., 9, 1990
6MJM
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BU of 6mjm by Molmil
Substrate Free Cytochrome P450 3A5 (CYP3A5)
分子名称: Cytochrome P450 3A5, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE
著者Hsu, M.H, Johnson, E.F.
登録日2018-09-21
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Active-site differences between substrate-free and ritonavir-bound cytochrome P450 (CYP) 3A5 reveal plasticity differences between CYP3A5 and CYP3A4.
J.Biol.Chem., 294, 2019
5FMK
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BU of 5fmk by Molmil
Bcl-xL with Bak BH3 complex
分子名称: BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, BCL-XL, GLYCEROL
著者Fairlie, W.D, Lee, E.F, Smith, B.J, Czabotar, P.E, Colman, P.M.
登録日2015-11-06
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.731 Å)
主引用文献Physiological Restraint of Bak by Bcl-Xl is Essential for Cell Survival.
Genes Dev., 30, 2016
5FMI
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BU of 5fmi by Molmil
Human Bak Q77L
分子名称: BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, ZINC ION
著者Fairlie, W.D, Lee, E.F, Smith, B.J.
登録日2015-11-06
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.491 Å)
主引用文献Physiological Restraint of Bak by Bcl-Xl is Essential for Cell Survival.
Genes Dev., 30, 2016
7LVE
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BU of 7lve by Molmil
Jug r 2 Leader Sequence Residues 117-161
分子名称: Vicilin Jug r 2.0101
著者Mueller, G.A, Foo, A.C.Y, DeRose, E.F.
登録日2021-02-25
公開日2022-02-02
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure, Immunogenicity, and IgE Cross-Reactivity among Walnut and Peanut Vicilin-Buried Peptides.
J.Agric.Food Chem., 70, 2022
7LVG
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BU of 7lvg by Molmil
Jug r 2 Leader Sequence Residues 69-111
分子名称: Vicilin Jug r 2.0101
著者Mueller, G.A, Foo, A.C.Y, DeRose, E.F.
登録日2021-02-25
公開日2022-02-02
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure, Immunogenicity, and IgE Cross-Reactivity among Walnut and Peanut Vicilin-Buried Peptides.
J.Agric.Food Chem., 70, 2022
7LVF
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BU of 7lvf by Molmil
Jug R 2 Leader Sequence Residues 1-57
分子名称: Vicilin Jug r 2.0101
著者Mueller, G.A, Foo, A.C.Y, DeRose, E.F.
登録日2021-02-25
公開日2022-02-02
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure, Immunogenicity, and IgE Cross-Reactivity among Walnut and Peanut Vicilin-Buried Peptides.
J.Agric.Food Chem., 70, 2022
6TRG
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BU of 6trg by Molmil
Salmonella typhimurium neuraminidase mutant (D100S)
分子名称: GLYCEROL, PHOSPHATE ION, Sialidase
著者Garman, E.F, Salinger, M.T, Murray, J.W, Laver, W.G, Kuhn, P, Vimr, E.R.
登録日2019-12-18
公開日2020-01-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Salmonella typhimurium neuraminidase mutant (D100S)
To Be Published
6TVI
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BU of 6tvi by Molmil
Salmonella typhimurium mutant neuraminidase (D100S)+ DANA
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, GLYCEROL, Sialidase
著者Garman, E.F, Salinger, M.T, Murray, J.W, Laver, W.G, Kuhn, P, Vimr, E.R.
登録日2020-01-09
公開日2020-02-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Salmonella typhimurium mutant neuraminidase (D100S)+ DANA
To Be Published

221716

件を2024-06-26に公開中

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