5FMJ

Bcl-xL with mouse Bak BH3 Q75L complex

Summary for 5FMJ

Entry DOI	10.2210/pdb5fmj/pdb
Related	5FMI 5FMK
Descriptor	BCL-2-LIKE PROTEIN 1, BAK1 PROTEIN, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	bcl-xl, bak, bh3 domain, apoptosis, bcl-2 family
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817
Total number of polymer chains	2
Total formula weight	22023.58
Authors	Fairlie, W.D.,Lee, E.F.,Smith, B.J. (deposition date: 2015-11-06, release date: 2016-06-01, Last modification date: 2024-01-10)
Primary citation	Lee, E.F.,Grabow, S.,Chappaz, S.,Dewson, G.,Hockings, C.,Kluck, R.M.,Gray, D.H.,Witkowski, M.T.,Evangelista, M.,Pettikiriarachchi, A.,Bouillet, P.,Lane, R.M.,Czabotar, P.E.,Colman, P.M.,Smith, B.J.,Kile, B.T.,Fairlie, W.D. Physiological Restraint of Bak by Bcl-Xl is Essential for Cell Survival. Genes Dev., 30:1240-, 2016 Cited by PubMed: 27198225 DOI: 10.1101/GAD.279414.116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.43 Å)

Structure validation