6MJM
Substrate Free Cytochrome P450 3A5 (CYP3A5)
Summary for 6MJM
| Entry DOI | 10.2210/pdb6mjm/pdb |
| Related | 5veu |
| Descriptor | Cytochrome P450 3A5, PROTOPORPHYRIN IX CONTAINING FE, GLYCEROL, ... (4 entities in total) |
| Functional Keywords | cytochrome p450, monooxygenase, membrane protein, drug metabolism, oxidoreductase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 55755.36 |
| Authors | Hsu, M.H.,Johnson, E.F. (deposition date: 2018-09-21, release date: 2019-04-03, Last modification date: 2023-10-11) |
| Primary citation | Hsu, M.H.,Johnson, E.F. Active-site differences between substrate-free and ritonavir-bound cytochrome P450 (CYP) 3A5 reveal plasticity differences between CYP3A5 and CYP3A4. J.Biol.Chem., 294:8015-8022, 2019 Cited by PubMed: 30926609DOI: 10.1074/jbc.RA119.007928 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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