7D25
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![BU of 7d25 by Molmil](/molmil-images/mine/7d25) | Hsp90 alpha N-terminal domain in complex with a 14 compund | Descriptor: | 6-chloranyl-9-[(4-methylphenyl)methyl]purin-2-amine, Heat shock protein HSP 90-alpha | Authors: | Shin, S.C, Kim, E.E. | Deposit date: | 2020-09-15 | Release date: | 2021-07-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90. Int J Mol Sci, 21, 2020
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6AV9
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![BU of 6av9 by Molmil](/molmil-images/mine/6av9) | CryoEM structure of Mical Oxidized Actin (Class 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | Authors: | Grintsevich, E.E, Ge, P, Sawaya, M.R, Yesilyurt, H.G, Terman, J.R, Zhou, Z.H, Reisler, E. | Deposit date: | 2017-09-01 | Release date: | 2018-01-17 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Catastrophic disassembly of actin filaments via Mical-mediated oxidation. Nat Commun, 8, 2017
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6G9I
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![BU of 6g9i by Molmil](/molmil-images/mine/6g9i) | Crystal structure of Ebolavirus glycoprotein in complex with clomipramine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, Envelope glycoprotein,Envelope glycoprotein, ... | Authors: | Zhao, Y, Ren, J, Fry, E.E, Xiao, J, Townsend, A.R, Stuart, D.I. | Deposit date: | 2018-04-10 | Release date: | 2018-05-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs. J. Med. Chem., 61, 2018
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6BM8
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![BU of 6bm8 by Molmil](/molmil-images/mine/6bm8) | Crystal structure of glycoprotein B from Herpes Simplex Virus type I | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein B, ... | Authors: | Cooper, R.S, Heldwein, E.E. | Deposit date: | 2017-11-13 | Release date: | 2018-05-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Structural basis for membrane anchoring and fusion regulation of the herpes simplex virus fusogen gB. Nat. Struct. Mol. Biol., 25, 2018
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6AVB
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![BU of 6avb by Molmil](/molmil-images/mine/6avb) | CryoEM structure of Mical Oxidized Actin (Class 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | Authors: | Grintsevich, E.E, Ge, P, Sawaya, M.R, Yesilyurt, H.G, Terman, J.R, Zhou, Z.H, Reisler, E. | Deposit date: | 2017-09-01 | Release date: | 2018-01-17 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Catastrophic disassembly of actin filaments via Mical-mediated oxidation. Nat Commun, 8, 2017
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6I2K
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![BU of 6i2k by Molmil](/molmil-images/mine/6i2k) | Structure of EV71 complexed with its receptor SCARB2 | Descriptor: | 1-(2-aminopyridin-4-yl)-3-[(3S)-5-{4-[(E)-(ethoxyimino)methyl]phenoxy}-3-methylpentyl]imidazolidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhou, D, Zhao, Y, Kotecha, A, Fry, E.E, Kelly, J, Wang, X, Rao, Z, Rowlands, D.J, Ren, J, Stuart, D.I. | Deposit date: | 2018-11-01 | Release date: | 2018-11-28 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2. Nat Microbiol, 4, 2019
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5ZQL
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![BU of 5zql by Molmil](/molmil-images/mine/5zql) | |
6QK4
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![BU of 6qk4 by Molmil](/molmil-images/mine/6qk4) | Lytic transglycosylase, LtgG, of Burkholderia pseudomallei. | Descriptor: | Membrane-bound lytic murein transglycosylase A | Authors: | Jenkins, C.H, Wallis, R, Allcock, N, Barnes, K.B, Richards, M.I, Auty, J.M, Galyov, E.E, Harding, S.V, Mukamolova, G.V. | Deposit date: | 2019-01-28 | Release date: | 2019-08-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | The lytic transglycosylase, LtgG, controls cell morphology and virulence in Burkholderia pseudomallei. Sci Rep, 9, 2019
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6QJR
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![BU of 6qjr by Molmil](/molmil-images/mine/6qjr) | Crystal structure of a DNA dodecamer containing a tetramethylpyrrolinoxyl (nitroxide) spin label | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*AP*AP*AP*AP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*TP*TP*TP*TP*(5NO)P*GP*CP*G)-3') | Authors: | Hardwick, J.S, Haugland, M.M, Ptchelkine, D, Brown, T, Anderson, E.E. | Deposit date: | 2019-01-24 | Release date: | 2020-02-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | 2'-Alkynyl spin-labelling is a minimally perturbing tool for DNA structural analysis. Nucleic Acids Res., 48, 2020
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6WR1
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![BU of 6wr1 by Molmil](/molmil-images/mine/6wr1) | Human steroidogenic cytochrome P450 17A1 mutant N52Y with inhibitor abiraterone | Descriptor: | Abiraterone, PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase | Authors: | Petrunak, E.M, Bart, A.G, Scott, E.E. | Deposit date: | 2020-04-29 | Release date: | 2021-05-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site. J.Biol.Chem., 299, 2023
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6WR0
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![BU of 6wr0 by Molmil](/molmil-images/mine/6wr0) | Human steroidogenic cytochrome P450 17A1 with 3-keto-delta4-abiraterone analog | Descriptor: | (8alpha)-17-(pyridin-3-yl)androsta-4,16-dien-3-one, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Petrunak, E.M, Bart, A.G, Scott, E.E. | Deposit date: | 2020-04-29 | Release date: | 2021-05-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site. J.Biol.Chem., 299, 2023
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6WW0
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![BU of 6ww0 by Molmil](/molmil-images/mine/6ww0) | Human steroidogenic cytochrome P450 17A1 with 3-keto-5alpha-abiraterone analog | Descriptor: | (5alpha,8alpha)-17-(pyridin-3-yl)androst-16-en-3-one, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Petrunak, E.M, Bart, A.G, Scott, E.E. | Deposit date: | 2020-05-07 | Release date: | 2021-05-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site. J.Biol.Chem., 299, 2023
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1HPV
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1HC8
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![BU of 1hc8 by Molmil](/molmil-images/mine/1hc8) | CRYSTAL STRUCTURE OF A CONSERVED RIBOSOMAL PROTEIN-RNA COMPLEX | Descriptor: | 58 NUCLEOTIDE RIBOSOMAL 23S RNA DOMAIN, MAGNESIUM ION, OSMIUM ION, ... | Authors: | Conn, G.L, Draper, D.E, Lattman, E.E, Gittis, A.G. | Deposit date: | 2001-04-27 | Release date: | 2002-05-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A Compact RNA Tertiary Structure Contains a Buried Backbone-K+ Complex J.Mol.Biol., 318, 2002
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6XYH
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![BU of 6xyh by Molmil](/molmil-images/mine/6xyh) | NMR solution structure of alpha-AnmTX-Ms11a-2 (Ms11a-2) | Descriptor: | AMS3 | Authors: | Mineev, K.S, Kornilov, F.D, Lushpa, V.A, Logashina, Y.A, Maleeva, E.E, Andreev, Y.A. | Deposit date: | 2020-01-30 | Release date: | 2021-02-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | NMR solution structure of alpha-AnmTX-Ms11a-2 (Ms11a-2) To Be Published
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6QJS
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![BU of 6qjs by Molmil](/molmil-images/mine/6qjs) | Crystal structure of a DNA dodecamer containing a tetramethylpiperidinoxyl (nitroxide) spin label | Descriptor: | COBALT HEXAMMINE(III), DNA (5'-D(P*GP*CP*AP*AP*AP*TP*TP*(S6M)P*GP*CP*G)-3') | Authors: | Hardwick, J.S, Haugland, M.M, Ptchelkine, D, Brown, T, Anderson, E.E. | Deposit date: | 2019-01-24 | Release date: | 2020-02-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | 2'-Alkynyl spin-labelling is a minimally perturbing tool for DNA structural analysis. Nucleic Acids Res., 48, 2020
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6XYI
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![BU of 6xyi by Molmil](/molmil-images/mine/6xyi) | NMR solution structure of alpha-AnmTX- Ms11a-3 (Ms11a-3) | Descriptor: | AMS9.3.1 | Authors: | Mineev, K.S, Kornilov, F.D, Lushpa, V.A, Logashina, Y.A, Maleeva, E.E, Andreev, Y.A. | Deposit date: | 2020-01-30 | Release date: | 2021-02-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | NMR solution structure of alpha-AnmTX- Ms11a-3 (Ms11a-3) TO BE PUBLISHED
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6YM0
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![BU of 6ym0 by Molmil](/molmil-images/mine/6ym0) | Crystal structure of the SARS-CoV-2 receptor binding domain in complex with CR3022 Fab (crystal form 1) | Descriptor: | Spike glycoprotein, heavy chain, light chain | Authors: | Huo, J, Zhao, Y, Ren, J, Zhou, D, Ginn, H.M, Fry, E.E, Owens, R, Stuart, D.I. | Deposit date: | 2020-04-07 | Release date: | 2020-04-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (4.36 Å) | Cite: | Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike. Cell Host Microbe, 28, 2020
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6SNW
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![BU of 6snw by Molmil](/molmil-images/mine/6snw) | Structure of Coxsackievirus A10 complexed with its receptor KREMEN1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, Capsid protein VP3, ... | Authors: | Zhao, Y, Zhou, D, Ni, T, Karia, D, Kotecha, A, Wang, X, Rao, Z, Jones, E.Y, Fry, E.E, Ren, J, Stuart, D.I. | Deposit date: | 2019-08-27 | Release date: | 2020-01-15 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10. Nat Commun, 11, 2020
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6SMG
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![BU of 6smg by Molmil](/molmil-images/mine/6smg) | Structure of Coxsackievirus A10 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Zhao, Y, Zhou, D, Ni, T, Karia, D, Kotecha, A, Wang, X, Rao, Z, Jones, E.Y, Fry, E.E, Ren, J, Stuart, D.I. | Deposit date: | 2019-08-21 | Release date: | 2020-01-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10. Nat Commun, 11, 2020
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6SNB
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![BU of 6snb by Molmil](/molmil-images/mine/6snb) | Structure of Coxsackievirus A10 A-particle | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Zhao, Y, Zhou, D, Ni, T, Karia, D, Kotecha, A, Wang, X, Rao, Z, Jones, E.Y, Fry, E.E, Ren, J, Stuart, D.I. | Deposit date: | 2019-08-23 | Release date: | 2020-01-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10. Nat Commun, 11, 2020
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1GEN
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![BU of 1gen by Molmil](/molmil-images/mine/1gen) | C-TERMINAL DOMAIN OF GELATINASE A | Descriptor: | CALCIUM ION, CHLORIDE ION, GELATINASE A, ... | Authors: | Libson, A.M, Gittis, A.G, Collier, I.E, Marmer, B.L, Goldberg, G.G, Lattman, E.E. | Deposit date: | 1995-07-19 | Release date: | 1996-08-17 | Last modified: | 2018-03-21 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of the haemopexin-like C-terminal domain of gelatinase A. Nat.Struct.Biol., 2, 1995
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1IMW
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![BU of 1imw by Molmil](/molmil-images/mine/1imw) | Peptide Antagonist of IGFBP-1 | Descriptor: | IGFBP-1 antagonist | Authors: | Lowman, H.B, Chen, Y.M, Skelton, N.J, Mortensen, D.L, Tomlinson, E.E, Sadick, M.D, Robinson, I.C, Clark, R.G. | Deposit date: | 2001-05-11 | Release date: | 2001-05-30 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1. Biochemistry, 40, 2001
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1ICE
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![BU of 1ice by Molmil](/molmil-images/mine/1ice) | STRUCTURE AND MECHANISM OF INTERLEUKIN-1BETA CONVERTING ENZYME | Descriptor: | INTERLEUKIN-1 BETA CONVERTING ENZYME, TETRAPEPTIDE ALDEHYDE | Authors: | Wilson, K.P, Griffith, J.P, Kim, E.E, Navia, M.A. | Deposit date: | 1994-09-29 | Release date: | 1995-07-28 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure and mechanism of interleukin-1 beta converting enzyme. Nature, 370, 1994
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1GJE
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![BU of 1gje by Molmil](/molmil-images/mine/1gje) | Peptide Antagonist of IGFBP-1, Minimized Average Structure | Descriptor: | IGFBP-1 antagonist | Authors: | Lowman, H.B, Chen, Y.M, Skelton, N.J, Mortensen, D.L, Tomlinson, E.E, Sadick, M.D, Robinson, I.C, Clark, R.G. | Deposit date: | 2001-05-11 | Release date: | 2001-05-30 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1. Biochemistry, 40, 2001
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