3UGB
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![BU of 3ugb by Molmil](/molmil-images/mine/3ugb) | UbcH5c~Ubiquitin Conjugate | 分子名称: | GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3 | 著者 | Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S. | 登録日 | 2011-11-02 | 公開日 | 2012-05-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates. Biochemistry, 51, 2012
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5WCW
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![BU of 5wcw by Molmil](/molmil-images/mine/5wcw) | Phosphotriesterase variant S3 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | 登録日 | 2017-07-02 | 公開日 | 2019-01-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.457 Å) | 主引用文献 | Phosphotriesterase variant S4 To Be Published
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5W7H
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![BU of 5w7h by Molmil](/molmil-images/mine/5w7h) | Supercharged arPTE variant R5 | 分子名称: | Phosphotriesterase, ZINC ION | 著者 | Campbell, E, Grant, J, Wang, Y, Sandhu, M, Williams, R.J, Nisbet, D.R, Perriman, A, Lupton, D, Jackson, C.J. | 登録日 | 2017-06-19 | 公開日 | 2019-01-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Hydrogel-Immobilized Supercharged Proteins Adv Biosyst, 2018
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5WH8
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![BU of 5wh8 by Molmil](/molmil-images/mine/5wh8) | Cellulase Cel5C_n | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PENTAETHYLENE GLYCOL, ... | 著者 | Koropatkin, N.M, Pope, P.B, Naas, A.E. | 登録日 | 2017-07-15 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | "Candidatus Paraporphyromonas polyenzymogenes" encodes multi-modular cellulases linked to the type IX secretion system. Microbiome, 6, 2018
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4OD0
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![BU of 4od0 by Molmil](/molmil-images/mine/4od0) | Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea | 分子名称: | 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | 著者 | Lee, K.S.S, Liu, J, Wagner, K.M, Pakhomova, S, Dong, H, Morisseau, C, Fu, S.H, Yang, J, Wang, P, Ulu, A, Mate, C, Nguyen, L, Wullf, H, Eldin, M.L, Mara, A.A, Newcomer, M.E, Zeldin, D.C, Hammock, B.D. | 登録日 | 2014-01-09 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J.Med.Chem., 57, 2014
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4ODG
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![BU of 4odg by Molmil](/molmil-images/mine/4odg) | Crystal structure of Staphylococcal nuclease variant V23I/V66I/V74I/V99I at cryogenic temperature | 分子名称: | CALCIUM ION, PHOSPHATE ION, THYMIDINE-3',5'-DIPHOSPHATE, ... | 著者 | Caro, J.A, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | 登録日 | 2014-01-10 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Pressure effects in proteins To be Published
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4ODP
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![BU of 4odp by Molmil](/molmil-images/mine/4odp) | Structure of SlyD delta-IF from Thermus thermophilus in complex with S2-W23A peptide | 分子名称: | 30S ribosomal protein S2, CALCIUM ION, CHLORIDE ION, ... | 著者 | Quistgaard, E.M, Low, C, Nordlund, P. | 登録日 | 2014-01-10 | 公開日 | 2015-01-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | 主引用文献 | Molecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyD. BMC Biol., 14, 2016
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5WIA
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![BU of 5wia by Molmil](/molmil-images/mine/5wia) | Crystal structure of the segment, GNNSYS, from the low complexity domain of TDP-43, residues 370-375 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2017-07-18 | 公開日 | 2018-04-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.002 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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8S5N
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![BU of 8s5n by Molmil](/molmil-images/mine/8s5n) | RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-24 | 公開日 | 2024-04-10 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8RKS
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![BU of 8rks by Molmil](/molmil-images/mine/8rks) | Structure of VPS29-VPS35 bound to the LFa motif R21 of Fam21. | 分子名称: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35, WASH complex subunit 2A | 著者 | Romano-Moreno, M, Astorga-Simon, E.N, Rojas, A.L, Hierro, A. | 登録日 | 2023-12-30 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Retromer-mediated recruitment of the WASH complex involves discrete interactions between VPS35, VPS29, and FAM21. Protein Sci., 33, 2024
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3UC8
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![BU of 3uc8 by Molmil](/molmil-images/mine/3uc8) | Trp-cage cyclo-TC1 - tetragonal crystal form | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, cyclo-TC1 | 著者 | Scian, M, Le Trong, I, Stenkamp, R.E, Andersen, N.H. | 登録日 | 2011-10-26 | 公開日 | 2012-07-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Crystal and NMR structures of a Trp-cage mini-protein benchmark for computational fold prediction. Proc.Natl.Acad.Sci.USA, 109, 2012
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3UCJ
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![BU of 3ucj by Molmil](/molmil-images/mine/3ucj) | Coccomyxa beta-carbonic anhydrase in complex with acetazolamide | 分子名称: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CHLORIDE ION, Carbonic anhydrase, ... | 著者 | Huang, S, Hainzl, T, Sauer-Eriksson, A.E. | 登録日 | 2011-10-27 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural studies of [beta]-carbonic anhydrase from the green alga Coccomyxa: inhibitor complexes with anions and acetazolamide. Plos One, 6, 2011
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3UEH
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![BU of 3ueh by Molmil](/molmil-images/mine/3ueh) | Crystal structure of human Survivin H80A mutant | 分子名称: | 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 5, DI(HYDROXYETHYL)ETHER, ... | 著者 | Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W. | 登録日 | 2011-10-30 | 公開日 | 2012-03-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres. Mol Biol Cell, 23, 2012
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3UF0
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![BU of 3uf0 by Molmil](/molmil-images/mine/3uf0) | Crystal structure of a putative NAD(P) dependent gluconate 5-dehydrogenase from Beutenbergia cavernae(EFI target EFI-502044) with bound NADP (low occupancy) | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2011-10-31 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a putative NAD(P) dependent gluconate 5-dehydrogenase from Beutenbergia cavernae(EFI target EFI-502044) with bound NADP (low occupancy) To be Published
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3USJ
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8S55
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![BU of 8s55 by Molmil](/molmil-images/mine/8s55) | RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state a (composite structure) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8S51
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![BU of 8s51 by Molmil](/molmil-images/mine/8s51) | RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8SBH
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![BU of 8sbh by Molmil](/molmil-images/mine/8sbh) | YeiE effector binding domain from E. coli | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Momany, C, Nune, M, Brondani, J.C, Afful, D, Neidle, E. | 登録日 | 2023-04-03 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | FinR, a LysR-type transcriptional regulator involved in sulfur homeostasis with homologs in diverse microorganisms To Be Published
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8S52
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![BU of 8s52 by Molmil](/molmil-images/mine/8s52) | RNA polymerase II core initially transcribing complex with an ordered RNA of 10 nt | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8RTZ
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![BU of 8rtz by Molmil](/molmil-images/mine/8rtz) | The structure of E. coli penicillin binding protein 3 (PBP3) in complex with a bicyclic peptide inhibitor | 分子名称: | 1,1',1''-(1,3,5-triazinane-1,3,5-triyl)tripropan-1-one, Bicyclic peptide inhibitor, Peptidoglycan D,D-transpeptidase FtsI | 著者 | Newman, H, Rowland, C.E, Dods, R, Lewis, N, Stanway, S.J, Bellini, D, Beswick, P. | 登録日 | 2024-01-29 | 公開日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Discovery and chemical optimisation of a Potent, Bi-cyclic (Bicycle) Antimicrobial Inhibitor of Escherichia coli PBP3 To Be Published
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6LHX
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![BU of 6lhx by Molmil](/molmil-images/mine/6lhx) | Crystal structure of ThsA | 分子名称: | ThsA | 著者 | Bae, E, Ka, D, Oh, H. | 登録日 | 2019-12-10 | 公開日 | 2020-06-24 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Structural and functional evidence of bacterial antiphage protection by Thoeris defense system via NAD+degradation. Nat Commun, 11, 2020
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8S54
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![BU of 8s54 by Molmil](/molmil-images/mine/8s54) | RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state b (composite structure) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabber, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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4WFA
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![BU of 4wfa by Molmil](/molmil-images/mine/4wfa) | The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with linezolid | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.E. | 登録日 | 2014-09-14 | 公開日 | 2015-10-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.392 Å) | 主引用文献 | Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus. Proc.Natl.Acad.Sci.USA, 112, 2015
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4WPM
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4WQ2
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![BU of 4wq2 by Molmil](/molmil-images/mine/4wq2) | Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound | 分子名称: | (2Z)-3-(6-bromo-1H-indol-3-yl)-2-sulfanylprop-2-enoic acid, 1,2-ETHANEDIOL, CALCIUM ION, ... | 著者 | Adams, S.E, Rizkallah, P.J, Miller, D.J, Hallett, M.B, Allemann, R.K. | 登録日 | 2014-10-21 | 公開日 | 2015-09-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Conformationally restricted calpain inhibitors. Chem Sci, 6, 2015
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