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PDB: 41371 results

6XMS
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BU of 6xms by Molmil
Structure of P5A-ATPase Spf1, AlF4-bound form
Descriptor: MAGNESIUM ION, P5A-type ATPase, TETRAFLUOROALUMINATE ION
Authors:Park, E, Sim, S.I.
Deposit date:2020-06-30
Release date:2020-09-23
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase.
Science, 369, 2020
6GYO
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BU of 6gyo by Molmil
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
Authors:Shintre, C.A, Pike, A.C.W, Tessitore, A, Young, M, Bushell, S.R, Strain-Damerell, C, Mukhopadhyay, S, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2018-06-30
Release date:2019-05-01
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
To Be Published
4RYK
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BU of 4ryk by Molmil
Crystal structure of a putative transcriptional regulator from Listeria monocytogenes EGD-e
Descriptor: DI(HYDROXYETHYL)ETHER, L(+)-TARTARIC ACID, Lmo0325 protein, ...
Authors:Filippova, E.V, Wawrzak, Z, Minasov, G, Kiryukhina, O, Jedrzejczak, R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-12-15
Release date:2015-01-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal structure of a putative transcriptional regulator from Listeria monocytogenes EGD-e
To be Published
6XSI
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BU of 6xsi by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS V104T at cryogenic temperature
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Robinson, A.C, Schlessman, J.L, Garcia-Moreno E, B.
Deposit date:2020-07-15
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Staphylococcal nuclease variant Delta+PHS V104T at cryogenic temperature
To be Published
6SYX
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BU of 6syx by Molmil
Hydrogenase-2 variant R479K - reduced sample exposed to pure oxygen
Descriptor: CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ...
Authors:Carr, S.B, Beaton, S.E, Evans, R.M, Armstrong, F.A.
Deposit date:2019-10-01
Release date:2020-10-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Hydrogen activation by NiFe-hydrogenases - consolidating the role of the pendant arginine.
To Be Published
6SD0
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BU of 6sd0 by Molmil
Structure of beta-galactosidase from Thermotoga maritima.
Descriptor: Beta-galactosidase, MAGNESIUM ION
Authors:Jimenez-Ortega, E, Ramirez-Escudero, M, Sanz-Aparicio, J.
Deposit date:2019-07-26
Release date:2020-01-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The cryo-EM Structure ofThermotoga maritimabeta-Galactosidase: Quaternary Structure Guides Protein Engineering.
Acs Chem.Biol., 15, 2020
5JNT
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BU of 5jnt by Molmil
Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with MES
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ...
Authors:Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N.
Deposit date:2016-04-30
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
8B29
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BU of 8b29 by Molmil
Human carbonic anhydrase II containing 6-fluorotryptophanes.
Descriptor: Carbonic anhydrase 2, ZINC ION
Authors:Pham, L.B.T, Costantino, A, Barbieri, L, Calderone, V, Luchinat, E, Banci, L.
Deposit date:2022-09-13
Release date:2023-01-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Direct Expression of Fluorinated Proteins in Human Cells for 19 F In-Cell NMR Spectroscopy.
J.Am.Chem.Soc., 145, 2023
3JC6
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BU of 3jc6 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
Descriptor: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
Authors:Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
Deposit date:2015-11-24
Release date:2016-02-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
2I3C
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BU of 2i3c by Molmil
Crystal Structure of an Aspartoacylase from Homo Sapiens
Descriptor: Aspartoacylase, PHOSPHATE ION, ZINC ION
Authors:Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2006-08-17
Release date:2006-08-29
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.
Proc.Natl.Acad.Sci.Usa, 104, 2007
5JAJ
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BU of 5jaj by Molmil
Structure of chicken LGP2 witha 5'p 10-mer dsRNA and ADP-AlF4-Mg.
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, LGP2, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-12
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
8DLD
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BU of 8dld by Molmil
Crystal structure of chalcone-isomerase like protein from Physcomitrella patens (PpCHIL-A)
Descriptor: Chalcone-flavonone isomerase family protein
Authors:Wolf Saxon, E, Moorman, C, Castro, A, Ruiz, A, Mallari, J.P, Burke, J.R.
Deposit date:2022-07-07
Release date:2023-05-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Regulatory ligand binding in plant chalcone isomerase-like (CHIL) proteins.
J.Biol.Chem., 299, 2023
6MMV
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BU of 6mmv by Molmil
Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* Extracellular Domain in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E.
Deposit date:2018-10-01
Release date:2018-11-28
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.71 Å)
Cite:Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor.
Cell, 175, 2018
6SPG
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BU of 6spg by Molmil
Pseudomonas aeruginosa 70s ribosome from a clinical isolate
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Halfon, Y, Jimenez-Fernande, A, La Ros, R, Espinos, R, Krogh Johansen, H, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S, Yonath, A.
Deposit date:2019-09-01
Release date:2019-10-16
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Proc.Natl.Acad.Sci.USA, 116, 2019
5JB2
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BU of 5jb2 by Molmil
Crystal structure of chicken LGP2 with 5'ppp 10-mer dsRNA and ADP-AlF4-Mg2+ at 2.2 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, LGP2, MAGNESIUM ION, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
6FLM
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BU of 6flm by Molmil
Crystal structure of the human TRIM25 PRYSPRY domain
Descriptor: CHLORIDE ION, E3 ubiquitin/ISG15 ligase TRIM25, SULFATE ION
Authors:Cusack, S, Kowalinski, E.
Deposit date:2018-01-26
Release date:2018-05-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
6SUD
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BU of 6sud by Molmil
Structure of L320A mutant of Rex8A from Paenibacillus barcinonensis complexed with xylose.
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Reducing-end xylose-releasing exo-oligoxylanase Rex8A, ...
Authors:Jimenez-Ortega, E, Ramirez-Escudero, M, Sanz-Aparicio, J.
Deposit date:2019-09-13
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural analysis of the reducing-end xylose-releasing exo-oligoxylanase Rex8A from Paenibacillus barcinonensis BP-23 deciphers its molecular specificity.
Febs J., 287, 2020
6GQL
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BU of 6gql by Molmil
Crystal structure of human c-KIT kinase domain in complex with AZD3229-analogue (compound 35)
Descriptor: Mast/stem cell growth factor receptor Kit, ~{N}-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-2-(4-propan-2-yl-1,2,3-triazol-1-yl)ethanamide
Authors:Schimpl, M, Hardy, C.J, Ogg, D.J, Overman, R.C, Packer, M.J, Kettle, J.G, Anjum, R, Barry, E, Bhavsar, D, Brown, C, Campbell, A, Goldberg, K, Grondine, M, Guichard, S, Hunt, T, Jones, O, Li, X, Moleva, O, Pearson, S, Shao, W, Smith, A, Smith, J, Stead, D, Stokes, S, Tucker, M, Ye, Y.
Deposit date:2018-06-07
Release date:2018-09-19
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors.
J. Med. Chem., 61, 2018
8DLC
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BU of 8dlc by Molmil
Crystal structure of chalcone-isomerase like protein from Vitis vinifera (VvCHIL)
Descriptor: Chalcone-flavonone isomerase family protein
Authors:Wolf Saxon, E, Moorman, C, Castro, A, Ruiz, A, Mallari, J.P, Burke, J.R.
Deposit date:2022-07-07
Release date:2023-05-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Regulatory ligand binding in plant chalcone isomerase-like (CHIL) proteins.
J.Biol.Chem., 299, 2023
6H2Z
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BU of 6h2z by Molmil
The crystal structure of human carbonic anhydrase II in complex with 4-(4-phenylpiperidine-1-carbonyl)benzenesulfonamide.
Descriptor: 4-(4-phenylpiperidin-1-yl)carbonylbenzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Buemi, M.R, Di Fiore, A, De Luca, L, Ferro, S, Mancuso, F, Monti, S.M, Buonanno, M, Angeli, A, Russo, E, De Sarro, G, Supuran, C.T, De Simone, G, Gitto, R.
Deposit date:2018-07-17
Release date:2018-12-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety.
Eur J Med Chem, 163, 2018
6H33
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BU of 6h33 by Molmil
The crystal structure of human carbonic anhydrase II in complex with 4-(4-phenyl)-4-hydroxy-1-piperidine-1-carbonyl)benzenesulfonamide.
Descriptor: 4-(4-oxidanyl-4-phenyl-piperidin-1-yl)carbonylbenzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Buemi, M.R, Di Fiore, A, De Luca, L, Ferro, S, Mancuso, F, Monti, S.M, Buonanno, M, Angeli, A, Russo, E, De Sarro, G, Supuran, C.T, De Simone, G, Gitto, R.
Deposit date:2018-07-17
Release date:2018-12-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety.
Eur J Med Chem, 163, 2018
6SHY
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BU of 6shy by Molmil
Structure of L320A/H321S double mutant of Rex8A from Paenibacillus barcinonensis
Descriptor: 1,2-ETHANEDIOL, Reducing-end xylose-releasing exo-oligoxylanase Rex8A
Authors:Jimenez-Ortega, E, Ramirez-Escudero, M, Sanz-Aparicio, J.
Deposit date:2019-08-08
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural analysis of the reducing-end xylose-releasing exo-oligoxylanase Rex8A from Paenibacillus barcinonensis BP-23 deciphers its molecular specificity.
Febs J., 287, 2020
3J8I
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BU of 3j8i by Molmil
Near-Atomic Resolution for One State of F-Actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Galkin, V.E.
Deposit date:2014-11-06
Release date:2015-01-14
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Near-atomic resolution for one state of f-actin.
Structure, 23, 2015
2I05
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BU of 2i05 by Molmil
Escherichia Coli Replication Terminator Protein (Tus) Complexed With TerA DNA
Descriptor: 5'-D(*T*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*CP*T)-3', 5'-D(*TP*AP*GP*TP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3', DNA replication terminus site-binding protein, ...
Authors:Oakley, A.J, Mulcair, M.D, Schaeffer, P.M, Dixon, N.E.
Deposit date:2006-08-10
Release date:2007-08-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Polarity of Termination of DNA Replication in E. coli
To be Published
3JSD
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BU of 3jsd by Molmil
Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G.
Deposit date:2009-09-10
Release date:2010-09-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
To be Published

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PDB entries from 2024-11-13

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