5KDS
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![BU of 5kds by Molmil](/molmil-images/mine/5kds) | ZmpB metallopeptidase in complex with an O-glycopeptide (a2,6-sialylated core-3 pentapeptide). | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)]2-acetamido-2-deoxy-alpha-D-galactopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Noach, I, Ficko-Blean, E, Stuart, C, Boraston, A.B. | Deposit date: | 2016-06-08 | Release date: | 2017-01-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Recognition of protein-linked glycans as a determinant of peptidase activity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8E05
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![BU of 8e05 by Molmil](/molmil-images/mine/8e05) | Structure of dimeric LRRK1 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 1 | Authors: | Reimer, J.M, Lin, Y.X, Leschziner, A.E. | Deposit date: | 2022-08-08 | Release date: | 2023-08-30 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structure of LRRK1 and mechanisms of autoinhibition and activation. Nat.Struct.Mol.Biol., 30, 2023
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1PR0
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![BU of 1pr0 by Molmil](/molmil-images/mine/1pr0) | Escherichia coli Purine Nucleoside Phosphorylase Complexed with Inosine and Phosphate/Sulfate | Descriptor: | INOSINE, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type | Authors: | Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. | Deposit date: | 2003-06-19 | Release date: | 2003-11-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase. J.Biol.Chem., 278, 2003
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3UJK
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![BU of 3ujk by Molmil](/molmil-images/mine/3ujk) | Crystal structure of protein phosphatase ABI2 | Descriptor: | MAGNESIUM ION, Protein phosphatase 2C 77 | Authors: | Zhou, X.E, Soon, F.-F, Ng, L.-M, Kovach, A, Tan, M.H.E, Suino-Powell, K.M, He, Y, Xu, Y, Brunzelle, J.S, Li, J, Melcher, K, Xu, H.E. | Deposit date: | 2011-11-07 | Release date: | 2012-02-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases. Science, 335, 2012
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3GLS
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![BU of 3gls by Molmil](/molmil-images/mine/3gls) | Crystal Structure of Human SIRT3 | Descriptor: | NAD-dependent deacetylase sirtuin-3, mitochondrial, SULFATE ION, ... | Authors: | Jin, L, Wei, W, Jiang, Y, Peng, H, Cai, J, Mao, C, Dai, H, Bemis, J.E, Jirousek, M.R, Milne, J.C, Westphal, C.H, Perni, R.B. | Deposit date: | 2009-03-12 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes. J.Biol.Chem., 284, 2009
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1K0W
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![BU of 1k0w by Molmil](/molmil-images/mine/1k0w) | CRYSTAL STRUCTURE OF L-RIBULOSE-5-PHOSPHATE 4-EPIMERASE | Descriptor: | L-RIBULOSE 5 PHOSPHATE 4-EPIMERASE, ZINC ION | Authors: | Luo, Y, Samuel, J, Mosimann, S.C, Lee, J.E, Strynadka, N.C.J. | Deposit date: | 2001-09-21 | Release date: | 2003-01-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of L-ribulose-5-phosphate 4-epimerase: an aldolase-like platform for epimerization Biochemistry, 40, 2001
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8DSW
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![BU of 8dsw by Molmil](/molmil-images/mine/8dsw) | |
6OFX
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![BU of 6ofx by Molmil](/molmil-images/mine/6ofx) | Non-rotated ribosome (Structure I) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | Deposit date: | 2019-04-01 | Release date: | 2019-09-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
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8AKU
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![BU of 8aku by Molmil](/molmil-images/mine/8aku) | 250 A SynPspA rod after incubation with ATP | Descriptor: | Chloroplast membrane-associated 30 kD protein | Authors: | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | Deposit date: | 2022-07-31 | Release date: | 2024-02-14 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat.Struct.Mol.Biol., 2024
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2WHJ
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![BU of 2whj by Molmil](/molmil-images/mine/2whj) | Understanding how diverse mannanases recognise heterogeneous substrates | Descriptor: | ACETATE ION, BETA-MANNANASE, GLYCEROL, ... | Authors: | Tailford, L.E, Ducros, V.M.A, Flint, J.E, Roberts, S.M, Morland, C, Zechel, D.L, Smith, N, Bjornvad, M.E, Borchert, T.V, Wilson, K.S, Davies, G.J, Gilbert, H.J. | Deposit date: | 2009-05-05 | Release date: | 2009-05-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates. Biochemistry, 48, 2009
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8AKY
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![BU of 8aky by Molmil](/molmil-images/mine/8aky) | 290 A SynPspA rod after incubation with ATP | Descriptor: | Chloroplast membrane-associated 30 kD protein | Authors: | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | Deposit date: | 2022-07-31 | Release date: | 2024-02-14 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat.Struct.Mol.Biol., 2024
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6OIT
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![BU of 6oit by Molmil](/molmil-images/mine/6oit) | CryoEM structure of Arabidopsis DDR' complex (DRD1 peptide-DMS3-RDM1) | Descriptor: | Protein CHROMATIN REMODELING 35, Protein DEFECTIVE IN MERISTEM SILENCING 3, Protein RDM1 | Authors: | Wongpalee, S.P, Liu, S, Zhou, Z.H, Jacobsen, S.E. | Deposit date: | 2019-04-09 | Release date: | 2019-07-24 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation. Nat Commun, 10, 2019
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8AKZ
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![BU of 8akz by Molmil](/molmil-images/mine/8akz) | 320 A SynPspA rod after incubation with ATP | Descriptor: | Chloroplast membrane-associated 30 kD protein | Authors: | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | Deposit date: | 2022-07-31 | Release date: | 2024-02-14 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat.Struct.Mol.Biol., 2024
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6OJ5
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![BU of 6oj5 by Molmil](/molmil-images/mine/6oj5) | In situ structure of rotavirus VP1 RNA-dependent RNA polymerase (TLP_RNA) | Descriptor: | Inner capsid protein VP2, RNA-directed RNA polymerase | Authors: | Jenni, S, Salgado, E.N, Herrmann, T, Li, Z, Grant, T, Grigorieff, N, Trapani, S, Estrozi, L.F, Harrison, S.C. | Deposit date: | 2019-04-10 | Release date: | 2019-04-24 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase. J.Mol.Biol., 431, 2019
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6HQN
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![BU of 6hqn by Molmil](/molmil-images/mine/6hqn) | Crystal structure of GcoA F169L bound to guaiacol | Descriptor: | Cytochrome P450, Guaiacol, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Mallinson, S.J.B, Hinchen, D.J, Allen, M.D, Johnson, C.W, Beckham, G.T, McGeehan, J.E. | Deposit date: | 2018-09-25 | Release date: | 2019-07-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Enabling microbial syringol conversion through structure-guided protein engineering. Proc.Natl.Acad.Sci.USA, 116, 2019
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8AL0
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![BU of 8al0 by Molmil](/molmil-images/mine/8al0) | 365 A SynPspA rod after incubation with ATP | Descriptor: | Chloroplast membrane-associated 30 kD protein | Authors: | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | Deposit date: | 2022-07-31 | Release date: | 2024-02-14 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat.Struct.Mol.Biol., 2024
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8AKX
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![BU of 8akx by Molmil](/molmil-images/mine/8akx) | 305 A SynPspA rod after incubation with ATP | Descriptor: | Chloroplast membrane-associated 30 kD protein | Authors: | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | Deposit date: | 2022-07-31 | Release date: | 2024-02-14 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat.Struct.Mol.Biol., 2024
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1BLZ
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![BU of 1blz by Molmil](/molmil-images/mine/1blz) | ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ACV-FE-NO COMPLEX) | Descriptor: | FE (III) ION, ISOPENICILLIN N SYNTHASE, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ... | Authors: | Roach, P.L, Clifton, I.J, Hensgens, C.M.H, Shibata, N, Schofield, C.J, Hajdu, J, Baldwin, J.E. | Deposit date: | 1998-07-22 | Release date: | 1999-01-13 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation. Nature, 387, 1997
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8AKV
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![BU of 8akv by Molmil](/molmil-images/mine/8akv) | 270 A SynPspA rod after incubation with ATP | Descriptor: | Chloroplast membrane-associated 30 kD protein | Authors: | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | Deposit date: | 2022-07-31 | Release date: | 2024-02-14 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat.Struct.Mol.Biol., 2024
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8AKW
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![BU of 8akw by Molmil](/molmil-images/mine/8akw) | 280 A SynPspA rod after incubation with ATP | Descriptor: | Chloroplast membrane-associated 30 kD protein | Authors: | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | Deposit date: | 2022-07-31 | Release date: | 2024-02-14 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat.Struct.Mol.Biol., 2024
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2Q4D
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![BU of 2q4d by Molmil](/molmil-images/mine/2q4d) | Ensemble refinement of the crystal structure of a lysine decarboxylase-like protein from Arabidopsis thaliana gene At5g11950 | Descriptor: | 1,2-ETHANEDIOL, Lysine decarboxylase-like protein At5g11950, NITRATE ION | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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6TW4
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![BU of 6tw4 by Molmil](/molmil-images/mine/6tw4) | HumRadA22F in complex with compound 6 | Descriptor: | CALCIUM ION, DNA repair and recombination protein RadA, ~{N}-[2-[(2~{S})-2-[[(1~{S})-1-(4-methoxyphenyl)ethyl]carbamoyl]pyrrolidin-1-yl]-2-oxidanylidene-ethyl]quinoline-2-carboxamide | Authors: | Marsh, M.E, Scott, D.E, Coyne, A.G, Skidmore, J, Abell, C, Hyvonen, M. | Deposit date: | 2020-01-12 | Release date: | 2021-01-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death. Cell Chem Biol, 28, 2021
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2Q4T
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![BU of 2q4t by Molmil](/molmil-images/mine/2q4t) | Ensemble refinement of the protein crystal structure of a cytosolic 5'-nucleotidase III from Mus musculus Mm.158936 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cytosolic 5'-nucleotidase III | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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6HUE
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![BU of 6hue by Molmil](/molmil-images/mine/6hue) | ParkinS65N | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | Authors: | McWilliams, T.G, Barini, E, Pohjolan-Pirhonen, R, Brooks, S.P, Singh, F, Burel, S, Balk, K, Kumar, A, Montava-Garriga, L, Prescott, A.R, Hassoun, S.M, Mouton-Liger, F, Ball, G, Hills, R, Knebel, A, Ulusoy, A, Di Monte, D.A, Tamjar, J, Antico, O, Fears, K, Smith, L, Brambilla, R, Palin, E, Valori, M, Eerola-Rautio, J, Tienari, P, Corti, O, Dunnett, S.B, Ganley, I.G, Suomalainen, A, Muqit, M.M.K. | Deposit date: | 2018-10-07 | Release date: | 2018-10-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Phosphorylation of Parkin at serine 65 is essential for its activation in vivo . Open Biology, 8, 2018
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5TLG
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![BU of 5tlg by Molmil](/molmil-images/mine/5tlg) | Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with (E)-4,4''-dihydroxy-3'-((hydroxyiminio)methyl)-[1,1':2',1''-terphenyl]-4'-olate | Descriptor: | 2~3~-[(E)-(hydroxyimino)methyl][1~1~,2~1~:2~2~,3~1~-terphenyl]-1~4~,2~4~,3~4~-triol, Estrogen receptor, NUCLEAR RECEPTOR COACTIVATOR 2 | Authors: | Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Nowak, J, Kojetin, D.J, Elemento, O, Katzenellenbogen, J.A, Nettles, K.W. | Deposit date: | 2016-10-11 | Release date: | 2017-01-18 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.228 Å) | Cite: | Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies. Cell Chem Biol, 24, 2017
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