8DSW

Crystal structure of EGFR kinase domain, Exon20 Insertion FQEA mutant

Summary for 8DSW

• Entry DOI: 10.2210/pdb8dsw/pdb
• Descriptor: Epidermal growth factor receptor, TETRAETHYLENE GLYCOL, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: egfr kinase domain, exon 20 insertion mutant., oncoprotein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 39030.88

Authors

Park, E.,Eck, M.J. (deposition date: 2022-07-23, release date: 2023-09-27)

• Primary citation: Park, E.,Eck, M.J.; Structural basis for oncogenic activation of the epidermal growth factor receptor by the InsFQEA exon 20 insertion; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.39 Å)