6PUR
| Human TRPM2 bound to ADPR | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Transient receptor potential cation channel subfamily M member 2 | Authors: | Du, J, Lu, W, Huang, Y. | Deposit date: | 2019-07-18 | Release date: | 2019-09-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel. Elife, 8, 2019
|
|
6PUO
| Human TRPM2 in the apo state | Descriptor: | Transient receptor potential cation channel subfamily M member 2 | Authors: | Du, J, Lu, W, Huang, Y. | Deposit date: | 2019-07-18 | Release date: | 2019-09-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel. Elife, 8, 2019
|
|
6PUU
| Human TRPM2 bound to 8-Br-cADPR and calcium | Descriptor: | (2R,3R,4S,5R,13R,14S,15R,16R)-24-amino-18-bromo-3,4,14,15-tetrahydroxy-7,9,11,25,26-pentaoxa-17,19,22-triaza-1-azonia-8 ,10-diphosphapentacyclo[18.3.1.1^2,5^.1^13,16^.0^17,21^]hexacosa-1(24),18,20,22-tetraene-8,10-diolate 8,10-dioxide, CALCIUM ION, Transient receptor potential cation channel subfamily M member 2 | Authors: | Du, J, Lu, W, Huang, Y. | Deposit date: | 2019-07-18 | Release date: | 2019-09-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel. Elife, 8, 2019
|
|
4IUP
| |
4IUV
| |
4IUT
| |
4IUQ
| crystal structure of SHH1 SAWADEE domain | Descriptor: | CYMAL-4, SAWADEE HOMEODOMAIN HOMOLOG 1, ZINC ION | Authors: | Du, J, Patel, D.J. | Deposit date: | 2013-01-21 | Release date: | 2013-05-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.809 Å) | Cite: | Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1. Nature, 498, 2013
|
|
4IUU
| |
3T2F
| Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, soaked with EDTA and DHAP | Descriptor: | Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | Authors: | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | Deposit date: | 2011-07-22 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase. Nature, 478, 2011
|
|
3T2C
| Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, DHAP-bound form | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | Authors: | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | Deposit date: | 2011-07-22 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase. Nature, 478, 2011
|
|
3T2B
| Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, ligand free | Descriptor: | Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | Authors: | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | Deposit date: | 2011-07-22 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase. Nature, 478, 2011
|
|
3T2E
| Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, F6P-bound form | Descriptor: | FRUCTOSE -6-PHOSPHATE, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | Authors: | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | Deposit date: | 2011-07-22 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase. Nature, 478, 2011
|
|
3T2G
| Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, Y229F variant with DHAP | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | Authors: | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | Deposit date: | 2011-07-22 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase. Nature, 478, 2011
|
|
3T2D
| Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, FBP-bound form | Descriptor: | 1,6-di-O-phosphono-D-fructose, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | Authors: | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | Deposit date: | 2011-07-22 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase. Nature, 478, 2011
|
|
3UIH
| |
3UIG
| |
3UII
| |
5WXV
| |
6DRJ
| Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, ADPR/Ca2+ bound state | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, Transient receptor potential cation channel, ... | Authors: | Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W. | Deposit date: | 2018-06-12 | Release date: | 2018-09-19 | Last modified: | 2018-10-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium. Nature, 562, 2018
|
|
6DRK
| Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, Apo state | Descriptor: | Transient receptor potential cation channel, subfamily M, member 2 | Authors: | Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W. | Deposit date: | 2018-06-12 | Release date: | 2018-09-19 | Last modified: | 2018-10-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium. Nature, 562, 2018
|
|
7N29
| Structure of NAD kinase | Descriptor: | NAD kinase 2, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Du, J, Estrella, M.A, Jeffrey, P.D, Korennykh, A.V. | Deposit date: | 2021-05-28 | Release date: | 2022-05-04 | Last modified: | 2022-06-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7EPB
| Cryo-EM structure of LY354740-bound mGlu2 homodimer | Descriptor: | (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, Anti-RON nanobody, Metabotropic glutamate receptor 2 | Authors: | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | Deposit date: | 2021-04-26 | Release date: | 2021-06-23 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
|
|
7EPC
| Cryo-EM structure of inactive mGlu7 homodimer | Descriptor: | Isoform 3 of Metabotropic glutamate receptor 7 | Authors: | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | Deposit date: | 2021-04-26 | Release date: | 2021-06-23 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
|
|
7EPD
| Cryo-EM structure of inactive mGlu2-7 heterodimer | Descriptor: | Isoform 3 of Metabotropic glutamate receptor 7, Metabotropic glutamate receptor 2,Peptidylprolyl isomerase | Authors: | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | Deposit date: | 2021-04-26 | Release date: | 2021-06-23 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
|
|
7EPA
| Cryo-EM structure of inactive mGlu2 homodimer | Descriptor: | Metabotropic glutamate receptor 2 | Authors: | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | Deposit date: | 2021-04-26 | Release date: | 2021-06-23 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
|
|