6PUU
Human TRPM2 bound to 8-Br-cADPR and calcium
Summary for 6PUU
Entry DOI | 10.2210/pdb6puu/pdb |
EMDB information | 20478 20479 20480 20482 |
Descriptor | Transient receptor potential cation channel subfamily M member 2, (2R,3R,4S,5R,13R,14S,15R,16R)-24-amino-18-bromo-3,4,14,15-tetrahydroxy-7,9,11,25,26-pentaoxa-17,19,22-triaza-1-azonia-8 ,10-diphosphapentacyclo[18.3.1.1^2,5^.1^13,16^.0^17,21^]hexacosa-1(24),18,20,22-tetraene-8,10-diolate 8,10-dioxide, CALCIUM ION (3 entities in total) |
Functional Keywords | trpm2 channel, 8-br-cadpr, calcium, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 691765.38 |
Authors | |
Primary citation | Huang, Y.,Roth, B.,Lu, W.,Du, J. Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel. Elife, 8:-, 2019 Cited by PubMed: 31513012DOI: 10.7554/eLife.50175 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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